Anti-CD8A Rat Monoclonal Antibody [clone: 53-6.7]

Supplier: Tonbo Biosciences
40-0081-U500 40-0081-U100 40-0081-M001
40-0081-U500EA 139 EUR
40-0081-U500 40-0081-U100 40-0081-M001
Anti-CD8A Rat Monoclonal Antibody [clone: 53-6.7]
Antibodies
The 53-6.7 antibody reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor in antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development,More Product Information
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SPECIFICATIONS

Antigen symbol CD8A CD8A
Environmentally Preferable
Antigen name CD8 antigen, alpha chain CD8 antigen, alpha chain
Antigen synonyms p32|Lyt-66|BB154331|Ly-2|Leu2|Ly-35|MAL|CD8|Ly-B p32|Lyt-66|BB154331|Ly-2|Leu2|Ly-35|MAL|CD8|Ly-B
Antibody type Primary Primary
Clonality Monoclonal Monoclonal
Conjugation Unconjugated Unconjugated
Clone 53-6.7 53-6.7
Reactivity Mouse Mouse
Host Rat Rat
Gene ID 14130/14131 12525
Isotype IgG2a kappa IgG2a kappa
ImmunoChemistry Yes Yes
ImmunoPrecipitation Yes Yes
Flow cytometry Yes Yes
Neutralisation Yes Yes
Cross adsorption none none
Storage temperature Cool Cool
Shipping temperature Ice Ice
Tested applications Functional assays, immunofluorescence microscopy Functional assays, immunofluorescence microscopy

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