Anti-CD4 Rat Monoclonal Antibody (PE (Phycoerythrin)rCP) [clone: RM4-5]

Supplier: Tonbo Biosciences
67-0042-U025 67-0042-U100
67-0042-U025EA 91.6 EUR
67-0042-U025 67-0042-U100
Anti-CD4 Rat Monoclonal Antibody (PE (Phycoerythrin)rCP) [clone: RM4-5]
Antibodies
The RM4-5 antibody reacts with mouse CD4, a 55 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta2-domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4 is typically expressed on thymocytes, certain mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells. The RM4-5 antibody is widelyMore Product Information
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