Anti-MITF Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Supplier: Bioss
BS-1990R-A488
BOSSBS-1990R-A488EA 901 EUR
BOSSBS-1990R-A488
Anti-MITF Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Antibodies
Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.

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