Anti-CR1 Mouse Monoclonal Antibody (CF640R) [clone: E11]

Supplier: Biotium
BNC400040-500 BNC400040-100
BNC400040-500EA 560 EUR
BNC400040-500 BNC400040-100
Anti-CR1 Mouse Monoclonal Antibody (CF640R) [clone: E11]
Antibodies
Recognizes a protein of 210-220 kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb is specific for a site in CR1 that is distal from the C3b-binding site, so that it is unable to block CR1 activity. This MAb is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21 /CD35 /CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.

Type: Primary
Antigen: CR1
Clonality: Monoclonal
Clone: E11
Conjugation: CF640R
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Baboon, Cynomolgus monkey, Human, Rhesus monkey
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