Anti-MYB Mouse Monoclonal Antibody (CF594) [clone: MYB286]

Supplier: Biotium
BNC940286-500 BNC940286-100
BNC940286-500EA 560 EUR
BNC940286-500 BNC940286-100
Anti-MYB Mouse Monoclonal Antibody (CF594) [clone: MYB286]
Antibodies
The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.

Type: Primary
Antigen: MYB
Clonality: Monoclonal
Clone: MYB286
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
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