Anti-NKX2-2 Mouse Monoclonal Antibody (CF647) [clone: NX2/294]

Supplier: Biotium
BNC470294-500 BNC470294-100
BNC470294-500EA 560 EUR
BNC470294-500 BNC470294-100
Anti-NKX2-2 Mouse Monoclonal Antibody (CF647) [clone: NX2/294]
Antibodies
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.

Type: Primary
Antigen: NKX2-2
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SPECIFICATIONS

Antigen symbol NKX2-2
Environmentally Preferable
Antigen name NK2 homeobox 2
Antigen synonyms NK2 transcription factor like protein B|NKX22|NK2 transcription factor related locus 2|Nkx2b|tinman|Homeobox protein NK-2 homolog B
Antibody type Primary
Clonality Monoclonal
Conjugation CF® 647
Clone Clone NX2/294
Reactivity Chicken,Human,Rat,Mouse
Host Mouse
Gene ID 516922
Isotype IgG2b kappa
ImmunoChemistry Yes
ImmunoFluorescence Yes
Concentration 0,1 mg/ml
Storage buffer PBS/0,1% BSA/0,05% azide

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