Anti-ITGAM Mouse Monoclonal Antibody (CF568) [clone: M1/70]

Supplier: Biotium
BNC680720-500 BNC680720-100
BNC680720-500EA 560 EUR
BNC680720-500 BNC680720-100
Anti-ITGAM Mouse Monoclonal Antibody (CF568) [clone: M1/70]
Antibodies
CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin αM combines with the Integrin β2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin αM/β2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. The protein CD11b has been implicated in the various adhesion-related interactions of cells such as monocytes, macrophages, natural killer (NK) cells, and granulocytes. It is part of a heterodimer that consists of CD11b and CD18. It also modulates the uptake of complement-coated particles within the cell. It is commonly used as a microglial marker in tissues derived from the nervous system.

Type: Primary
Antigen: ITGAM
Clonality: Monoclonal
Clone: M1/70
Conjugation: CF568
Epitope:
Host: Mouse
Isotype: IgG2b kappa
Reactivity: Baboon, Chimpanzee, Human, Mouse, Rabbit, Rhesus monkey
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR