Anti-TAG-72 / CA72.4 Mouse Monoclonal Antibody [clone: B72.3 CC49]

Supplier: Biotium
BNUB0738-500 BNUB0738-100
BNUB0738-500EA 511 EUR
BNUB0738-500 BNUB0738-100
Anti-TAG-72 / CA72.4 Mouse Monoclonal Antibody [clone: B72.3 CC49]
Antibodies
Recognizes an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.

  • Purified

Type: Primary
Antigen: TAG-72 / CA72.4
Clonality: Monoclonal
Clone: B72.3 CC49
Conjugation: Purified
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Cow, Dog, Human, Rat
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