Anti-TYR Mouse Monoclonal Antibody (CF405S) [clone: T311 OCA1/812]

Supplier: Biotium
BNC040908-500 BNC040908-100
BNC040908-500EA 560 EUR
BNC040908-500 BNC040908-100
Anti-TYR Mouse Monoclonal Antibody (CF405S) [clone: T311 OCA1/812]
Antibodies
Recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cellMore Product Information
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SPECIFICATIONS

Antigen symbol TYR
Antigen name Tyrosinase
Environmentally Preferable
Antigen synonyms Tumor rejection antigen AB|ATN|CMM8|SHEP3|Oculocutaneous albinism IA|Monophenol monooxygenase|OCA1A|OCA1|TYR|LB24-AB|SK29-AB
Antibody type Primary
Clonality Monoclonal
Conjugation CF® 405S
Clone Clone T311 OCA1/812
Reactivity Human
Host Mouse
Gene ID 503555
Isotype IgG
ImmunoChemistry Yes
ImmunoFluorescence Yes
Concentration 0,1 mg/ml
Storage buffer PBS/0,1% BSA/0,05% azide

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