Anti-SOX10 Mouse Monoclonal Antibody (CF405S) [clone: SOX10/991]

Supplier: Biotium
BNC040991-500 BNC040991-100
BNC040991-500EA 560 EUR
BNC040991-500 BNC040991-100
Anti-SOX10 Mouse Monoclonal Antibody (CF405S) [clone: SOX10/991]
Antibodies
Recognizes a protein of ~55 kDa, identified as SOX10. This MAb is highly specific and does not cross-react with other members of the SOX-family. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. SOX-10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by otherMore Product Information
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SPECIFICATIONS

Antigen symbol SOX10
Environmentally Preferable
Antigen synonyms Waardenburg syndrome type 2E (WS2E)|PCWH|WS4|SRY (sex determining region Y) box 10|Waardenburg syndrome type 4C (WS4C)|DOM|SRY box containing gene 10|SOX10|SRY related HMG box gene 10
Antibody type Primary
Clonality Monoclonal
Conjugation CF® 405S
Clone Clone SOX10/991
Reactivity Human
Host Mouse
Gene ID 376984
Isotype IgG2b kappa
Western blot Yes
ImmunoChemistry Yes
ImmunoFluorescence Yes
Concentration 0,1 mg/ml
Storage buffer PBS/0,1% BSA/0,05% azide

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