COX Colorimetric Inhibitor Screening Assay Kit

Supplier: Cayman Chemical
CAYM701050-192EA 1038 EUR
CAYM701050-192
COX Colorimetric Inhibitor Screening Assay Kit
Assays ELISAs
A colorimetric assay for the screening of isozyme-specific inhibitors.

  • Screen for inhibitors of ovine COX-1 or human COX-2
  • Measure the peroxidase component of the COX
  • Assay 41 samples for COX-1 and 41 samples for COX-2 in duplicate
  • Plate-based colorimetric measurement (590 nm)

Cayman's COX Colorimetric Inhibitor Screening Assay measures the peroxidase component of cyclooxygenases. The peroxidase activity is assayed colorimetrically by monitoring the appearance of oxidized N,N,N',N'-tetramethyl-p-phenylenediamine (TMPD) at 590 nm. Inhibition of COX activity, measured by TMPD oxidation, by a variety of selective and nonselective inhibitors, shows changed potencies similar to those observed with other in vitro methods. The COX Colorimetric Inhibitor Screening assay includes both ovine COX-1 and human recombinant COX-2 enzymes in order to screen isozyme-specific inhibitors. Cayman's COX Colorimetric Assay is a time saving tool for screening vast numbers of inhibitors.
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