Human Recombinant EN-TEV Protease (from E. coli)
Supplier: Abcam
Recombinant EN-TEV Protease protein is a Tobacco etch virus Fragment protein, in the 2038 to 2279 aa range, expressed in Escherichia coli, with >=95% purity and suitable for SDS-PAGE, Size Exclusion Chromatography.
bioactive
Applications: SDS-PAGE, Size Exclusion Chromatography
Helper component proteinase. Required for aphid transmission and also has proteolytic activity. Only cleaves a Gly-Gly dipeptide at its own C-terminus (PubMed:2656254). Interacts with virions and aphid stylets (PubMed:9880030). Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs (PubMed:11414807). May have RNA-binding activity. Cytoplasmic inclusion protein. Has helicase activity. It may be involved in replication. 6 kDa protein 1. Indispensable for virus replication (By similarity). Reduces the abundance of host transcripts related to jasmonic acid biosynthesis therefore altering the host defenses (By similarity). In order to increase its own stability, decreases host protein degradation pathways (By similarity). 6 kDa protein 2. Indispensable for virus replication. Viral genome-linked protein. Mediates the cap-independent, EIF4E-dependent translation of viral genomic RNAs (Probable). Binds to the cap-binding site of host EIF4E and thus interferes with the host EIF4E-dependent mRNA export and translation (By similarity). VPg-RNA directly binds EIF4E and is a template for transcription (By similarity). Also forms trimeric complexes with EIF4E-EIF4G, which are templates for translation (By similarity). Nuclear inclusion protein A. Has RNA-binding and proteolytic activities. Nuclear inclusion protein B. An RNA-dependent RNA polymerase that plays an essential role in the virus replication. Capsid protein. Involved in aphid transmission, cell-to-cell and systemis movement, encapsidation of the viral RNA and in the regulation of viral RNA amplification.
Caution:
All products are FOR RESEARCH USE ONLY. PRODUCTS ARE NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. Customer is granted a limited use non-exclusive licence for its own internal research. Any control manufacturer supplies with a Product is limited to use only to validate the relevant Product. By using the Product, Customers agree not to attempt to reverse engineer or otherwise perform any compositional, structural, functional or other analyses directed to learning the methodology, formulae, sequences, processes, make-up or production of any of the Products or portions thereof
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