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Product Image-DIDAPOD010240

Optical plate

Description: Optical glass components are manufactured with high accuracy polishing and flatness tolerance.
Catalog Number: DIDAPOD010240
UOM: 1 * 1 items
Supplier: DIDALAB
Product Image-BINH1003080

Diffraction/transmission gratings

Description: Transmission grating for spectroscopic examinations and for experiments on diffraction and interference. Suitable to resolve the sodium D lines.
Catalog Number: BINH1003080
UOM: 1 * 1 items
Supplier: 3B Scientific
Product Image-BINH1013885

Electron diffraction tube D

Description: Highly evacuated electron tube for determining the wavelength of electrons as a function of the anode voltage from the radii of the diffraction rings and the distance between the lattice planes of graphite (Debye-Scherrer-diffraction) and rendered visible on a fluorescent screen. Also intended for determining the wavelengths of monochromatic radiation at different anode voltages from the radii of the diffraction rings and the lattice plane spacing of graphite, as well as confirming de Broglie’s hypothesis.
Catalog Number: BINH1013885
UOM: 1 * 1 items
Supplier: 3B Scientific
Image Unavailable-BOSSBS-11528R-A680

Anti-GALR3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: GALR3 a 368 and 370 amino acid protein in human and rat, respectively, belongs to a family of G protein-coupled receptors that bind the neuropeptide galanin, which is distributed throughout the central and peripheral nervous system, the pituitary gland, the gastrointestinal tract and in the endocrine and exocrine pancreas. GALR3 mRNA is widely distributed, but expressed at low abundance. In human, GALR3 mRNA is highly expressed in the hypothalamus, pituitary and testis, and is expressed to a lesser extent in adrenal gland and pancreas. Rat and human GALR3 co-express with potassium channel subunits GIRK1 and GIRK4. Like GALR1, GALR3 Signalling pathways lead to the inhibition of adenylate cyclase and to the activation of potassium channels, which are linked to the regulation of neurotransmitter release. Binding of galanin to galanin receptors results in increased feeding, impaired learning, enhanced opiate analgesia and decreased opiate place preference.
Catalog Number: BOSSBS-11528R-A680
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-0175R-HRP

Anti-TRKB Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4. Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2. Upon ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades. Through SHC1, FRS2, SH2B1, SH2B2 activates the GRB2-Ras-MAPK cascade that regulates for instance neuronal differentiation including neurite outgrowth. Through the same effectors controls the Ras-PI3 kinase-AKT1 signaling cascade that mainly regulates growth and survival. Through PLCG1 and the downstream protein kinase C-regulated pathways controls synaptic plasticity. Thereby, plays a role in learning and memory by regulating both short term synaptic function and long-term potentiation. PLCG1 also leads to NF-Kappa-B activation and the transcription of genes involved in cell survival. Hence, it is able to suppress anoikis, the apoptosis resulting from loss of cell-matrix interactions. May also play a role in neutrophin-dependent calcium signaling in glial cells and mediate communication between neurons and glia.
Catalog Number: BOSSBS-0175R-HRP
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-0175R-A350

Anti-TRKB Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Description: Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4. Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2. Upon ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades. Through SHC1, FRS2, SH2B1, SH2B2 activates the GRB2-Ras-MAPK cascade that regulates for instance neuronal differentiation including neurite outgrowth. Through the same effectors controls the Ras-PI3 kinase-AKT1 signaling cascade that mainly regulates growth and survival. Through PLCG1 and the downstream protein kinase C-regulated pathways controls synaptic plasticity. Thereby, plays a role in learning and memory by regulating both short term synaptic function and long-term potentiation. PLCG1 also leads to NF-Kappa-B activation and the transcription of genes involved in cell survival. Hence, it is able to suppress anoikis, the apoptosis resulting from loss of cell-matrix interactions. May also play a role in neutrophin-dependent calcium signaling in glial cells and mediate communication between neurons and glia.
Catalog Number: BOSSBS-0175R-A350
UOM: 1 * 100 µl
Supplier: Bioss
Product Image-BE-417

Experimentation kits, affinity chromatography

Description: The Affinity Chromatography kit teaches the basic principle of affinity chromatography utilising highly specific affinity columns. This lab activity involves preparation of a crude protein extract and running affinity exchange chromatography for isolation of a protein.
Catalog Number: BE-417
UOM: 1 * 1 KIT
Supplier: G-Biosciences
Product Image-EDVOS-46

STEM concepts, agarose gel electrophoresis

Description: Link important STEM concepts using Agarose Gel Electrophoresis.
Catalog Number: EDVOS-46
UOM: 1 * 1 items
Supplier: EDVOTEK
Image Unavailable-BOSSBS-11528R

Anti-GALR3 Rabbit Polyclonal Antibody

Description: GALR3 a 368 and 370 amino acid protein in human and rat, respectively, belongs to a family of G protein-coupled receptors that bind the neuropeptide galanin, which is distributed throughout the central and peripheral nervous system, the pituitary gland, the gastrointestinal tract and in the endocrine and exocrine pancreas. GALR3 mRNA is widely distributed, but expressed at low abundance. In human, GALR3 mRNA is highly expressed in the hypothalamus, pituitary and testis, and is expressed to a lesser extent in adrenal gland and pancreas. Rat and human GALR3 co-express with potassium channel subunits GIRK1 and GIRK4. Like GALR1, GALR3 signaling pathways lead to the inhibition of adenylate cyclase and to the activation of potassium channels, which are linked to the regulation of neurotransmitter release. Binding of galanin to galanin receptors results in increased feeding, impaired learning, enhanced opiate analgesia and decreased opiate place preference.
Catalog Number: BOSSBS-11528R
UOM: 1 * 100 µl
Supplier: Bioss
Product Image-EDVO135

Using CRISPR to treat cystic fibrosis

Description: Hands-on simulation of CRISPR-Cas9 to target and treat Cystic Fibrosis.
Catalog Number: EDVO135
UOM: 1 * 1 KIT
Supplier: EDVOTEK
Product Image-EDVO116-C

Kits: sickle cell gene detection (DNA-based), Ready-to-Load™

Description: This Ready-to-Load™ kit shows how a restriction enzyme can be used to screen DNA for Sickle Cell Anaemia.
Catalog Number: EDVO116-C
UOM: 1 * 1 items
Supplier: EDVOTEK
Image Unavailable-BOSSBS-11528R-A488

Anti-GALR3 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: GALR3 a 368 and 370 amino acid protein in human and rat, respectively, belongs to a family of G protein-coupled receptors that bind the neuropeptide galanin, which is distributed throughout the central and peripheral nervous system, the pituitary gland, the gastrointestinal tract and in the endocrine and exocrine pancreas. GALR3 mRNA is widely distributed, but expressed at low abundance. In human, GALR3 mRNA is highly expressed in the hypothalamus, pituitary and testis, and is expressed to a lesser extent in adrenal gland and pancreas. Rat and human GALR3 co-express with potassium channel subunits GIRK1 and GIRK4. Like GALR1, GALR3 signaling pathways lead to the inhibition of adenylate cyclase and to the activation of potassium channels, which are linked to the regulation of neurotransmitter release. Binding of galanin to galanin receptors results in increased feeding, impaired learning, enhanced opiate analgesia and decreased opiate place preference.
Catalog Number: BOSSBS-11528R-A488
UOM: 1 * 100 µl
Supplier: Bioss
Product Image-DIDAPOD010007

Screens for optical bench

Description: Educational Materials, Optics, Application: Physics, Translucent screen 20×20 cm, attached to a rod with Ø 10 mm
Catalog Number: DIDAPOD010007
UOM: 1 * 1 items
Supplier: DIDALAB
Product Image-EDVO166

Experimentation kits, detection of a simulated infectious agent

Description: An infectious outbreak requires prompt and accurate identification of the biological agent. Often, early clinical symptoms are first identified in exposed individuals and then infectious agents are identified by lab tests. In this experiment, students transmit a simulated infectious agent (chemical dye) between classmates which is only visible under long UV light. The pattern of transmission and primary source is documented.
Catalog Number: EDVO166
UOM: 1 * 1 items
Supplier: EDVOTEK
Product Image-EDVOS-49

Kits: in search of my father, Ready-to-Load™

Description: Solve the mystery of two boys separated from their parents a decade ago. Their biological mother is identified by mitochondrial DNA and their biological father from chromosomal DNA.
Catalog Number: EDVOS-49
UOM: 1 * 1 items
Supplier: EDVOTEK
Product Image-BINH1002711

Electrochemistry kit

Description: Equipment set inclusive of digital multimeter for measuring electrochemical potentials of various metals in experiments.
Catalog Number: BINH1002711
UOM: 1 * 1 items
Supplier: 3B Scientific
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