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Catalog Number: (PRSI40-123)
Supplier: ProSci Inc.
Description: GLP-1 is a proglucagon-derived peptide hormone secreted primarily by intestinal L cells during feeding. Its major physiological function is stimulation of pancreatic β-cells to release appropriate amounts of insulin after glucose absorption. Other biological actions exhibited by GLP-1 include suppression of plasma glucagons levels, inhibition of gastric motility, and promotion of satiety. The secretion of GLP-1 from intestinal L cells is stimulated by nutrients, hormones, and neural inputs. On the other hand, insulin has been reported to inhibit GLP-1 release, indicating that a feedback loop mechanism regulates GLP-1 secretion. In addition to being the precursor of GLP-1, proglucagon, whose primary structure is highly conserved in mammalian species, is also the precursor for other members of the glucagon family of peptide hormones including glicentin-related pancreatic peptide (GRPP), glucagons, and GLP-2. Recombinant human GLP-1 is a 3.3 kDa consisting of 31 amino acid residues.
UOM: 1 * 200 µG


Supplier: Thermo Fisher Scientific
Description: 3,3-Dimethyl-1-butyne ≥98%
Catalog Number: (APOSOR948833-1G)
Supplier: Apollo Scientific
Description: (3,3-Dimethylcyclobutyl)methanamine
UOM: 1 * 1 g


Catalog Number: (APOSPC409042-1G)
Supplier: Apollo Scientific
Description: (3,3-Difluorocyclobutyl)ethanol
UOM: 1 * 1 g


Supplier: Biosensis
Description: The Biosensis Mouse and Rat proNGF Rapid enzyme-linked immunosorbent assay (ELISA) Kit is a sandwich ELISA that allows the quantification of rodent full-length proNGF protein in less than 4 hours in cell culture supernatants, cell lysates and tissue homogenates only if used as directed. This ELISA Kit has also successfully been used on mouse urine samples (Ryu JC et al., 2018). Please refer to the kit protocol for specific use instructions for each substrate application.

This ELISA kit contains a recombinant mouse proNGF standard expressed in E.coli and consists of a pre-coated anti-proNGF capture antibody, a biotinylated anti-proNGF detection antibody and horseradish peroxidase (HRP)-conjugated streptavidin. The addition of a substrate (3,3',5,5'-tetramethylbenzidine, TMB) yields a colored reaction product which is directly proportional to the concentration of proNGF present in samples and protein standards. A proNGF positive control (QC sample) is provided to assure consistent assay performance. This ELISA kit detects rat proNGF due to high degree of homology (96%) with mouse proNGF based on amino acid sequence, and the ability of this kit in detecting proNGF in rat PC12 cell lysates and rat brain tissue homogenate. In the absence of a true rat proNGF standard, results may be expressed as 'mouse proNGF equivalents'. This ELISA kit shows only 20% reactivity with the human form of proNGF and is therefore not suitable to quantify human proNGF. No cross-reactivity was observed with mature mouse NGF and full-length proBDNF when tested in assay buffer.

The antibodies used in this ELISA kit bind epitopes within the pro-domain (capture) and mature domain (detection) of the protein, thus this ELISA assay does not detect the pro-domain peptide. This kit has not been tested for other applications. Sufficient amount of proNGF standard is supplied to allow for spike- and recovery experiments in order to validate this ELISA assay for other sample matrices if required.

Catalog Number: (ACRO404050050)
Supplier: Thermo Fisher Scientific
Description: Appearance: Yellow to orange Crystalline powder or crystals
UOM: 1 * 5 g

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Supplier: Apollo Scientific
Description: 6-Bromo-2-oxaspiro[3.3]heptane

Supplier: Apollo Scientific
Description: 2-Thiaspiro[3.3]heptan-6-amine

Catalog Number: (APOSPC400053-250MG)
Supplier: Apollo Scientific
Description: 1-Bromo-3-(3,3-difluorocyclobutyl)benzene
UOM: 1 * 250 mg


Catalog Number: (APOSOR52315-1G)
Supplier: Apollo Scientific
Description: 3,3-Dimethyloxan-4-amine hydrochloride
UOM: 1 * 1 g


Supplier: Apollo Scientific
Description: Spiro[3.3]heptan-2-one

Supplier: Apollo Scientific
Description: Spiro[3.3]heptan-2-ol

Supplier: Apollo Scientific
Description: 3,3-Difluoro-1-boc-azetidine

Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Pierce TCEP-HCl is a potent, versatile, odorless, thiol-free reducing agent with broad application to protein and other research involving reduction of disulfide bonds. The unique compound is easily soluble and very stable in many aqueous solutions. TCEP reduces disulfide bonds as effectively as dithiothreitol (DTT), but unlike DTT and other thiol-containing reducing agents, TCEP does not have to be removed before certain sulfhydryl-reactive crosslinking reactions.
Supplier: Apollo Scientific
Description: (3,3-Difluorocyclobutyl)methanamine hydrochloride 97%

Catalog Number: (APOSPC430144-250MG)
Supplier: Apollo Scientific
Description: tert-Butyl 3,3-difluoropiperidin-4-ylcarbamate
UOM: 1 * 250 mg


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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