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Image Unavailable-PRSI24-194

Anti-CD52 Recombinant Antibody [Clone: YTH 34.5-G2b (Campath-1G)]

Description: Anti-CD52 Recombinant Antibody [Clone: YTH 34.5-G2b (Campath-1G)]
Catalog Number: PRSI24-194
UOM: 1 * 0,2 mg
Supplier: ProSci Inc.
Image Unavailable-BOSSBS-5223R-A750

Anti-BMX Tyr566 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Catalog Number: BOSSBS-5223R-A750
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-5537R-FITC

Anti-PDPK1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
Catalog Number: BOSSBS-5537R-FITC
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-2739R-A488

Anti-PDPK1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
Catalog Number: BOSSBS-2739R-A488
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-5223R-FITC

Anti-BMX Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
Catalog Number: BOSSBS-5223R-FITC
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-2765R-A488

Anti-BMX Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
Catalog Number: BOSSBS-2765R-A488
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-3567R-HRP

Anti-INPP5D Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall the protein functions as a negative regulator of myeliod cell proliferation and survival.
Catalog Number: BOSSBS-3567R-HRP
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-3398R-A555

Anti-INPP5D Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Description: SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall the protein functions as a negative regulator of myeliod cell proliferation and survival.
Catalog Number: BOSSBS-3398R-A555
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-3398R-A350

Anti-INPP5D Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Description: SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall the protein functions as a negative regulator of myeliod cell proliferation and survival.
Catalog Number: BOSSBS-3398R-A350
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-5545R-CY3

Anti-PDPK1 Rabbit Polyclonal Antibody (Cy3®)

Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
Catalog Number: BOSSBS-5545R-CY3
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-2765R-FITC

Anti-BMX Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
Catalog Number: BOSSBS-2765R-FITC
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-5223R-A488

Anti-BMX Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
Catalog Number: BOSSBS-5223R-A488
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-3132R-FITC

Anti-BMX Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
Catalog Number: BOSSBS-3132R-FITC
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-ENZOALX350318M025

(-)-Arctiin (from Arctium lappa) ≥95% (by HPLC)

Description: Lignan derivative with antitumor activities. Down-regulates anti-apoptotic protein Bcl-XL. Potent inhibitor of HIV type-I integrase and DNA topoisomerase II. Shows phytoestrogenic activity and is an antagonist for platelet activating factor and Ca²⁺.
Catalog Number: ENZOALX350318M025
UOM: 1 * 25 mg
Supplier: ENZO LIFE SCIENCES
Image Unavailable-BOSSBS-5537R-CY5.5

Anti-PDPK1 Rabbit Polyclonal Antibody (Cy5.5®)

Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
Catalog Number: BOSSBS-5537R-CY5.5
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-SOCO1.525.355

Accessories

Description: Telescopic feed tubing, FEP, 195 - 345 mm, for dispensers up 25 ml, Calibrex™
Catalog Number: SOCO1.525.355
UOM: 1 * 1 items
Supplier: Socorex Isba
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