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Image Unavailable-AGLSFP-1004-0275

BAC Kits

Description: Quality control of BAC digests and large DNA fragments using pulsed-field capillary electrophoresis.
Catalog Number: AGLSFP-1004-0275
UOM: 1 * 1 items
Supplier: AGILENT
Image Unavailable-BOSSBS-12928R

Anti-CYP26A1 Rabbit Polyclonal Antibody

Description: The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP26A1 is a major retinoic acid catabolic enzyme. CYP26A1 plays an important role in protecting tailbud tissues from inappropriate exposure to retinoic acid. CYP26A1 transcription is epigenetically regulated by nuclear retinoic acid receptor ∫2. Mutations in the gene encoding for CYP26A1 are associated with caudal agenesis and spina bifida, imperforate anus, agenesis of the caudal portions of the digestive and urogenital tracts, and malformed lumbosacral skeletal elements. CYP26A1 is upregulated in adenomatous polyposis coli mouse adenomas, human FAP adenomas, human sporadic colon carcinomas, and in the intestine of adenomatous polyposis coli (apcmcr) mutant zebrafish embryos.
Catalog Number: BOSSBS-12928R
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-12928R-CY3

Anti-CYP26A1 Rabbit Polyclonal Antibody (Cy3®)

Description: The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP26A1 is a major retinoic acid catabolic enzyme. CYP26A1 plays an important role in protecting tailbud tissues from inappropriate exposure to retinoic acid. CYP26A1 transcription is epigenetically regulated by nuclear retinoic acid receptor ∫2. Mutations in the gene encoding for CYP26A1 are associated with caudal agenesis and spina bifida, imperforate anus, agenesis of the caudal portions of the digestive and urogenital tracts, and malformed lumbosacral skeletal elements. CYP26A1 is upregulated in adenomatous polyposis coli mouse adenomas, human FAP adenomas, human sporadic colon carcinomas, and in the intestine of adenomatous polyposis coli (apcmcr) mutant zebrafish embryos.
Catalog Number: BOSSBS-12928R-CY3
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-12928R-A488

Anti-CYP26A1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP26A1 is a major retinoic acid catabolic enzyme. CYP26A1 plays an important role in protecting tailbud tissues from inappropriate exposure to retinoic acid. CYP26A1 transcription is epigenetically regulated by nuclear retinoic acid receptor ∫2. Mutations in the gene encoding for CYP26A1 are associated with caudal agenesis and spina bifida, imperforate anus, agenesis of the caudal portions of the digestive and urogenital tracts, and malformed lumbosacral skeletal elements. CYP26A1 is upregulated in adenomatous polyposis coli mouse adenomas, human FAP adenomas, human sporadic colon carcinomas, and in the intestine of adenomatous polyposis coli (apcmcr) mutant zebrafish embryos.
Catalog Number: BOSSBS-12928R-A488
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-5814R-CY5

Anti-PROM2 Rabbit Polyclonal Antibody (Cy5®)

Description: Prominin 2 is a 112 kDa glycoporotein structurally related to Prominin 1 (CD133) although amino acid similarity is not more than 30%, but their genomic organization is strikingly similar. Like Prominin 1, the prominin 2 exhibit similar membrane topology with 5 trans-membrane domains and two large glycosylated extracellular domains. Similar to Prominin1 localization, the Prominin 2 is also associated with membrane protrusions of the epithelial cells from adult kidney, and all along the digestive track and other epithelial tissues.Prominin 2 expression is down-regulated in aggressive prostate cancer cell lines and transient transfection of PROML2 expression vectors has been shown to induce apoptosis in cultured prostate cancer cells, suggesting a tumor suppressive role for Prominin 2. Prominin 2 expression is likely to be involved in growth suppression in the prostate, and down-regulation of Prominin 2 may disrupt normal prostatic homeostasis and lead to uncontrolled prostatic growth.
Catalog Number: BOSSBS-5814R-CY5
UOM: 1 * 100 µl
Supplier: Bioss
Product Image-APPCA2210.0500

Base materials

Description: Components of many microbiological growth media.
Catalog Number: APPCA2210.0500
UOM: 1 * 500 g
Supplier: PanReac AppliChem
Image Unavailable-BOSSBS-11621R-A680

Anti-Guanylin Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: The family of guanylin regulatory peptides, including guanylin and uroguanylin, are strongly expressed in intestinal mucosa and regulate intestinal fluid secretion during digestion. Guanylins are also involved in acid neutralization and the regulation of membrane-bound guanylate cyclase Signalling molecules. Guanylin and uroguanylin are secreted primarily in the stomach, intestine, and colon. Guanylin is also detected in plasma. Guanylin is an endogenous activator of intestinal guanylate cyclase. It stimulates intestinal guanylate cyclase through the same receptor binding region as the heat-stable enterotoxins. Gut enterochromaffin cells synthesize guanylin to be a prohormone of 115 amino acids which is then is processed to the molecular form of 94 amino acids. This 10 kDa form is found circulating in the blood.
Catalog Number: BOSSBS-11621R-A680
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-13374R

Anti-Gliadin Rabbit Polyclonal Antibody

Description: Gliadin is a glycoprotein that, along with glutenin, plays a role in the formation of gluten, an ergastic amorphous mixture of proteins found in wheat, rye, and barley. Gluten is responsible for the elasticity of kneaded dough, which allows it to be leavened. Gliadin is approximately 60% soluble in ethanol and contains only intramolecule disulfide links. Gliadin is also found in a variety of foods as well as in beer, along with the glycoprotein Hordein. Induction of zonulin release in intestinal epithelial cells is triggered by Gliadin. This causes an activation of the zonulin pathway by PKC mediated cytoskeleton reorganization and tight junction opening leads to a rapid increase in intestinal permeability to macromolecules. Individuals with disorders such as celiac disease or Crohn's disease are sensitive to Gliadin since they lack the enzyme necessary for its digestion and can not tolerate it in their diet.
Catalog Number: BOSSBS-13374R
UOM: 1 * 100 µl
Supplier: Bioss
Product Image-458-0048

Flask, Digesdahl®

Description: Specially designed glass flask for use with Digesdahl® digestion apparatus. Each flask is calibrated individually with a 100 ml (to contain) mark.
Catalog Number: 458-0048
UOM: 1 * 1 items
Supplier: Hach
Image Unavailable-BOSSBS-11177R-HRP

Anti-Trypsin Inhibitor Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins which play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. CRISP-8 (Cysteine-rich secretory protein 8), also known as PI15 (Peptidase inhibitor 15), P25TI or SugarCrisp, is a 258 amino acid secreted protein that belongs to the CRISP family. Expressed at low levels in thyroid, prostate, salivary and mammary tissue, CRISP-8 functions as a serine protease inhibitor that exhibits weak inhibitory action against Trypsin, a serine protease found in the digestive system. In addition to its role as a protease inhibitor, CRISP-8 is secreted in neuroblastoma and glioblastoma cell lines, suggesting a role for CRISP-8 in tumor formation and metastasis within the central nervous system.
Catalog Number: BOSSBS-11177R-HRP
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-11177R

Anti-Trypsin Inhibitor Rabbit Polyclonal Antibody

Description: Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins which play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. CRISP-8 (Cysteine-rich secretory protein 8), also known as PI15 (Peptidase inhibitor 15), P25TI or SugarCrisp, is a 258 amino acid secreted protein that belongs to the CRISP family. Expressed at low levels in thyroid, prostate, salivary and mammary tissue, CRISP-8 functions as a serine protease inhibitor that exhibits weak inhibitory action against Trypsin, a serine protease found in the digestive system. In addition to its role as a protease inhibitor, CRISP-8 is secreted in neuroblastoma and glioblastoma cell lines, suggesting a role for CRISP-8 in tumor formation and metastasis within the central nervous system.
Catalog Number: BOSSBS-11177R
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-ICNA0210255791

Pancreatin, MP Biomedicals

Description: Pancreatin are natural chemicals that help break down fats, proteins, and carbohydrates. Pancreatin is a digestive enzyme produced by the pancreas and delivered to the small intestine for the hydrolysis of complex nutrients.
Catalog Number: ICNA0210255791
UOM: 1 * 1 kg
Supplier: MP Biomedicals
Product Image-OZBICAS9050

Streptococcus pyogenes Cas9 nuclease

Description: Optimised Cas9 Nuclease <i>S. Pyogenes</i> is designed for genome editing in living cells or organisms and also for <i>in vitro</i> digestion.
Catalog Number: OZBICAS9050
UOM: 1 * 50 µG
Supplier: OZ BIOSCIENCES
Image Unavailable-BOSSBS-12928R-A680

Anti-CYP26A1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: The cytochrome P450 proteins (CYPs) are monooxygenases that catalyse many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP26A1 is a major retinoic acid catabolic enzyme. CYP26A1 plays an important role in protecting tailbud tissues from inappropriate exposure to retinoic acid. CYP26A1 transcription is epigenetically regulated by nuclear retinoic acid receptor 2. Mutations in the gene encoding for CYP26A1 are associated with caudal agenesis and spina bifida, imperforate anus, agenesis of the caudal portions of the digestive and urogenital tracts, and malformed lumbosacral skeletal elements. CYP26A1 is upregulated in adenomatous polyposis coli mouse adenomas, human FAP adenomas, human sporadic colon carcinomas, and in the intestine of adenomatous polyposis coli (apcmcr) mutant zebrafish embryos.
Catalog Number: BOSSBS-12928R-A680
UOM: 1 * 100 µl
Supplier: Bioss
Product Image-ICNA091689149

Pig trypsin (from pancreas), MP Biomedicals

Description: Trypsin-EDTA solution is widely used for cell dissociation, routine cell culture passaging, and primary tissue dissociation due to its digestive strength.
Catalog Number: ICNA091689149
UOM: 1 * 100 mL
Supplier: MP Biomedicals

MSDS Certificates


Image Unavailable-BOSSBS-1383R-CY7

Anti-CD13/APN/ANPEN Rabbit Polyclonal Antibody (Cy7®)

Description: Broad specificity aminopeptidase. Plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. May play a critical role in the pathogenesis of cholesterol gallstone disease. May be involved in the metabolism of regulatory peptides of diverse cell types, responsible for the processing of peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. Found to cleave antigen peptides bound to major histocompatibility complex class II molecules of presenting cells and to degrade neurotransmitters at synaptic junctions. Is also implicated as a regulator of IL-8 bioavailability in the endometrium, and therefore may contribute to the regulation of angiogenesis. Is used as a marker for acute myeloid leukemia and plays a role in tumor invasion. In case of human coronavirus 229E (HCoV-229E) infection, serves as receptor for HCoV-229E spike glycoprotein. Mediates as well human cytomegalovirus (HCMV) infection.
Catalog Number: BOSSBS-1383R-CY7
UOM: 1 * 100 µl
Supplier: Bioss
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