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Catalog Number: (BSENC-1700-100)
Supplier: Biosensis
Description: The heat shock proteins were discovered, as the name suggests, since they are heavily upregulated when cells are stressed by temperatures above the normal physiological range. They are expressed in unstressed cells also and have a normal function as chaperones, helping other proteins to fold correctly, and are required in much greater amounts if the cell or tissue is stressed by heat. The increased levels are generated transcriptionally under the influence of a powerful transcription factor, the heat shock factor 1 (HSF1). The different heat shock proteins were originally named based on their SDS-PAGE mobility, so HSP27 has an apparent molecular weight of 27kDa. It is an abundant protein even under non-stress conditions and frequently shows up as a major spot on 2 dimensional gels of cells or tissues. It is known to associate with a variety of other proteins such as actin, intermediate filament subunits and ubiquitin and is found both in the cytoplasm and the nucleus of cells. HSP27 can become heavily phosphorylated under the influence of multiple protein kinases particularly as a result of activation of the p38/SAPK pathway. Upregulation of this protein is protective against neurodegenerative diseases at least in certain mouse models (1). Point mutations in the HSP27 gene are associated with two neurological diseases, Charcot-Marie-Tooth disease type 2F and distal hereditary motor neuropathy IIB (2). These diseases are associated with axonal loss apparently following defects in the transport of neurofilaments.
UOM: 1 * 100 µl


Supplier: US Biological
Description: Anti-Heat Shock Protein 70, Geodia cydonium Rabbit Polyclonal Antibody

Catalog Number: (USBIH1834-41A)
Supplier: US Biological
Description: Anti-Heat Shock Protein 70 Interacting Protein Chicken Polyclonal Antibody
UOM: 1 * 50 µG


Catalog Number: (USBIH1834-41D)
Supplier: US Biological
Description: Anti-Heat Shock Protein 70 Interacting Protein Rabbit Polyclonal Antibody
UOM: 1 * 200 µl


Catalog Number: (804-0226)
Supplier: 3M MEDICAL
Description: This chemical indicator tape is designed for use as packaging tape and for the immediate identification of items exposed to dry heat processing.
UOM: 1 * 1 Roll

Catalog Number: (USBIH1830-52K)
Supplier: US Biological
Description: Anti-Heat Shock Protein 27, Mouse Monoclonal Antibody [clone: 6D435]
UOM: 1 * 100 µG


Catalog Number: (USBIH1831-58J-200)
Supplier: US Biological
Description: Anti-Heat Shock Protein 90 Mouse Monoclonal Antibody [clone: 10F730]
UOM: 1 * 200 µG


Catalog Number: (USBIH1830-70J-100)
Supplier: US Biological
Description: Anti-Heat Shock Protein 60 Mouse Monoclonal Antibody [clone: 8k273]
UOM: 1 * 100 µl


Catalog Number: (USBIH1834-15J-100)
Supplier: US Biological
Description: Anti-Heat Shock Protein 40 Mouse Monoclonal Antibody [clone: 10F735]
UOM: 1 * 100 µG


Catalog Number: (USBIH1834-15H-100)
Supplier: US Biological
Description: Anti-Heat Shock Protein 40 Mouse Monoclonal Antibody [clone: 10F734]
UOM: 1 * 100 µG


Supplier: GESTIGKEIT HARRY
Description: Can be universally employed as either an air, fluid or sandbath for heating many of the various receptactles in laboratory use, regardless of size or material, for temperatures ranging between 60 to 600 °C.

Catalog Number: (USBIH1834-30A-100)
Supplier: US Biological
Description: Anti-Heat Shock Protein 65 Mouse Monoclonal Antibody [clone: 4E124]
UOM: 1 * 100 µG


Supplier: US Biological
Description: Anti-Heat Shock Protein 90 Mouse Monoclonal Antibody [clone: 7G31]

Catalog Number: (USBIH1831-55J-200)
Supplier: US Biological
Description: Anti-Heat Shock Protein 90 Mouse Monoclonal Antibody [clone: 10F727]
UOM: 1 * 200 µG


Supplier: US Biological
Description: Anti-Heat Shock Protein 27 Mouse Monoclonal Antibody [clone: 10F714]

Catalog Number: (USBIH1830-48K)
Supplier: US Biological
Description: Anti-Heat Shock Protein 22 Mouse Monoclonal Antibody [clone: 10F616]
UOM: 1 * 100 µG


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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