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Image Unavailable-BOSSBS-1296R-CY5

Anti-DEFB2 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-1296R-CY5)
Supplier: Bioss
Description: Beta-defensin 2 (BD-2) also known as skin-antimicrobial peptide 1 (SAP1) is a peptide that is encoded by the DEFB4 (defensin, beta 4) gene. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. Beta-defensin 2 is an antibiotic peptide which is locally regulated by inflammation.
UOM: 1 * 100 µl
Image Unavailable-APOSBIN0135-100G

Neomycin sulphate

Supplier: Apollo Scientific
Description: Neomycin is an aminoglycoside antibiotic and has a bactericidal action against many gram-negative bacteria.

Certificates

Image Unavailable-ENZOALX380279M250

Vancomycin hydrochloride (from Streptomyces lysosup)

Supplier: ENZO LIFE SCIENCES
Description: Glycopeptide antibiotic. Interferes with cell wall synthesis. Effective against Gram-positive bacteria.

Image Unavailable-ENZOALX450008M025

Nonactin (from Streptomyces griseus) ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES
Description: Macrotetrolide antibiotic. Monovalent cation ionophore with high selectivity for ammonium and potassium. Specifically inhibits the processing of cytoplasmic precursor proteins destined for the mitochondria. Inhibits the effects on P170 glycoprotein-mediated efflux of chemotherapeutic agents in multidrug resistant (MDR) cancer cells.

Image Unavailable-ENZOBMLGR3000005

Actinomycin D (from Streptomyces parvulus) ≥98% (by TLC)

Catalog Number: (ENZOBMLGR3000005)
Supplier: ENZO LIFE SCIENCES
Description: An intercalating transcription inhibitor and antineoplastic antibiotic. Inhibits transcription by binding to DNA at dG residues. Induces apoptosis in many cell lines, but suppresses in PC12 cells induced by topoisomrease II inhibitor etopside. Used at 5-10 µg/mL in cell culture for halting transcription. The product is not sterile.
UOM: 1 * 5 mg
Image Unavailable-CAYM16000-1

Fosmidomycin sodium salt ≥95%, crystalline solid

Supplier: Cayman Chemical
Description: Fosmidomycin is an antibiotic originally isolated from culture broths of bacteria of the genus Streptomyces that inhibits DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis. Fosmidomycin is active against both Gram-negative and Gram-positive bacteria and the human malarial parasite P. falciparum (IC50 = 290-370 nM).

Image Unavailable-BOSSBS-2334R-A750

Anti-PXR Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-2334R-A750)
Supplier: Bioss
Description: Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by the antibiotic rifampicin and various plant metabolites, such as hyperforin, guggulipid, colupulone, and isoflavones. Response to specific ligands is species-specific. Activated by naturally occurring steroids, such as pregnenolone and progesterone. Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2334R-A647

Anti-PXR Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-2334R-A647)
Supplier: Bioss
Description: Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by the antibiotic rifampicin and various plant metabolites, such as hyperforin, guggulipid, colupulone, and isoflavones. Response to specific ligands is species-specific. Activated by naturally occurring steroids, such as pregnenolone and progesterone. Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2334R-FITC

Anti-PXR Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-2334R-FITC)
Supplier: Bioss
Description: Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by the antibiotic rifampicin and various plant metabolites, such as hyperforin, guggulipid, colupulone, and isoflavones. Response to specific ligands is species-specific. Activated by naturally occurring steroids, such as pregnenolone and progesterone. Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes.
UOM: 1 * 100 µl
Image Unavailable-CAYM16113-5

Cefoperazone sodium salt ≥95%, crystalline solid

Supplier: Cayman Chemical
Description: Cefoperazone is a cephalosporin antibiotic that is active in vitro against most Gram-positive and Gram-negative bacteria, including β-lactamase strains (3 – 4 µg/ml inhibits 90% of S. <i>aureus</i> growth). It has been studied in the treatment of upper and lower respiratory tract infections, urinary tract infections, gynecological infections, skin infections, as well as bacteremia.

MSDS

Image Unavailable-BOSSBS-2334R-CY5.5

Anti-PXR Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-2334R-CY5.5)
Supplier: Bioss
Description: Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by the antibiotic rifampicin and various plant metabolites, such as hyperforin, guggulipid, colupulone, and isoflavones. Response to specific ligands is species-specific. Activated by naturally occurring steroids, such as pregnenolone and progesterone. Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes.
UOM: 1 * 100 µl
Image Unavailable-ENZOBMLEI2800001

Geldanamycin ≥95% (by HPLC)

Supplier: ENZO LIFE SCIENCES
Description: Potent antitumor antibiotic. Inhibitor of pp60<sup>src</sup> tyrosine kinase and of c-myc gene expression in murine lymphoblastoma cells. Inhibits the transforming activity of abl, erbB, fps, src, and yes.

Image Unavailable-BOSSBS-1295R-CY3

Anti-DEFB2 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-1295R-CY3)
Supplier: Bioss
Description: Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Jul 2008]
UOM: 1 * 100 µl
Image Unavailable-59001.

Calcimycin (A23187) free acid ≥98% (by TLC) ionophore

Catalog Number: (59001.)
Supplier: Biotium
Description: A-23187, also known as Calcimycin or Calcium Ionophore III, is a calcium ionophore that rapidly equilibrates intracellular and extracellular calcium concentrations. It is commonly used for in situ calibrations of fluorescent calcium indicators. The ionophore allows Mn2 to enter the cells and quench intracellular fluorescence of calcium indicators.
UOM: 1 * 1 mg
Image Unavailable-ENZOBMLCT1070001

Thiolutin (from Streptomyces luteosporeus) ≥95% (by HPLC, TLC)

Supplier: ENZO LIFE SCIENCES
Description: Sulfur containing antibiotic. Potent inhibitor of bacterial and yeast RNA polymerases. Inhibits mRNA chain elongation. Inhibits adhesion of endothelial cells (HUVECs) to vitronectin (IC50=0.83 µM) thereby inhibiting tumor cell-induced angiogenesis in vivo. Inhibits transcription in C. albicans. Inhibits microbiological growth in beer. Active against soil borne pathogens.

Image Unavailable-BOSSBS-1296R-CY3

Anti-DEFB2 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-1296R-CY3)
Supplier: Bioss
Description: Beta-defensin 2 (BD-2) also known as skin-antimicrobial peptide 1 (SAP1) is a peptide that is encoded by the DEFB4 (defensin, beta 4) gene. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. Beta-defensin 2 is an antibiotic peptide which is locally regulated by inflammation.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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