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Image Unavailable-BOSSBS-7556R

Anti-5-lipoxygenase activating protein Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-7556R)
Supplier: Bioss
Description: Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1049R-FITC

Anti-CHRNA7 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-1049R-FITC)
Supplier: Bioss
Description: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0792R-A647

Anti-SERPINB5 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-0792R-A647)
Supplier: Bioss
Description: Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
UOM: 1 * 100 µl
Image Unavailable-CAYM15428-10

Lamotrigine ≥98%

Supplier: Cayman Chemical
Description: Lamotrigine is an inhibitor of voltage-gated sodium channels (Na<sub>v</sub>), blocking human Na<sub>v</sub>1,2, Na<sub>v</sub>1,5, and Na<sub>v</sub>1,8 with IC<sub>50</sub> values of 10, 62, and 96 μM, respectively.

Image Unavailable-BOSSBS-1346R-CY5.5

Anti-TRP73 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-1346R-CY5.5)
Supplier: Bioss
Description: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1049R-A680

Anti-CHRNA7 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-1049R-A680)
Supplier: Bioss
Description: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1235R-A750

Anti-Hyaluronidase-1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-1235R-A750)
Supplier: Bioss
Description: May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth (By similarity). Overexpression of HYAL1 suppressed the growth rate of colon carcinoma cell tumors in an experimental model.
UOM: 1 * 100 µl
Image Unavailable-CAYM14955-5

HA-100 hydrochloride ≥95%

Supplier: Cayman Chemical
Description: HA-100 is an isoquinoline compound with an added piperazinylsulfonyl group that acts as an inhibitor of protein kinases (PKs), including PKA, PKC, and PKG (IC<sub>50</sub>s = 8, 12 and 4 µM, respectively). It less effectively blocks the activity of myosin light chain kinase (IC<sub>50</sub> = 240 µM).

Image Unavailable-BOSSBS-0792R-A488

Anti-SERPINB5 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-0792R-A488)
Supplier: Bioss
Description: Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1235R-A647

Anti-HYAL1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-1235R-A647)
Supplier: Bioss
Description: May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth (By similarity). Overexpression of HYAL1 suppressed the growth rate of colon carcinoma cell tumors in an experimental model.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1346R-CY7

Anti-TRP73 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-1346R-CY7)
Supplier: Bioss
Description: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1049R-CY5.5

Anti-CHRNA7 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-1049R-CY5.5)
Supplier: Bioss
Description: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1235R-CY7

Anti-HYAL1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-1235R-CY7)
Supplier: Bioss
Description: May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth (By similarity). Overexpression of HYAL1 suppressed the growth rate of colon carcinoma cell tumors in an experimental model.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9051R-HRP

Anti-TRPM4 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-9051R-HRP)
Supplier: Bioss
Description: Calcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca(2+), it is impermeable to it. Mediates transport of monovalent cations (Na(+) >K(+) >Cs(+) >Li(+)), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca(2+) oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production. Involved in myogenic constriction of cerebral arteries. Controls insulin secretion in pancreatic beta-cells. May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca(2+) overload. Affects T-helper 1 (Th1) and T-helper 2 (Th2) cell motility and cytokine production through differential regulation of calcium signaling and NFATC1 localization. Enhances cell proliferation through up-regulation of the beta-catenin signaling pathway.Involvement in disease:Defects in TRPM4 are the cause of progressive familial heart block type 1B (PFHB1B) [MIM:604559]. It is a cardiac bundle branch disorder characterized by progressive alteration of cardiac conduction through the His-Purkinje system, with a pattern of a right bundle-branch block and/or left anterior hemiblock occurring individually or together. It leads to complete atrio-ventricular block causing syncope and sudden death.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8191R-FITC

Anti-CPPED1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-8191R-FITC)
Supplier: Bioss
Description: Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.
UOM: 1 * 100 µl
Product Image-720-0815

Embedding rings

Supplier: Simport Scientific
Description: PS. These embedding rings are suitable for holding and identifying tissue sample blocks and fit well in microtome chuck adapters.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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