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Description: Extracellular glycoproteins fibrillin-1 and -2 are major components of connective tissue microfibrils. Fibrillin-2 containing microfibrils regulate the early process of elastic fiber assembly in tissue. Mutations in the fibrillin-2 gene resulting in impaired assembly of fibrillin-2 may lead to molecular congenital contractural arachnodactyly. Fibrillin-2 constitutes the backbone of microfibrils which insert directly into the lamina densa of basement membranes. Epithelial cells primarily deposit fibrillin into the extracellular matrix in a nonfibrillar form. Mutations in the 8-cysteine motif of Fibrillin-2 alters its binding to microfibril-associated glycoprotein-1 (MAGP-1), which may increase the severity of congenital contractural arachnodactyly.
Catalog Number: BOSSBS-12166R-CY3
UOM: 1 * 100 µl
Supplier: Bioss


Description: Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC1, probably to facilitate the release of DNAJC1 from its substrate.
Catalog Number: BOSSBS-1219R-CY7
UOM: 1 * 100 µl
Supplier: Bioss


Description: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
Catalog Number: BOSSBS-3959R-CY5.5
UOM: 1 * 100 µl
Supplier: Bioss


Description: Location-regulated scaffolding protein connecting MEK to RAF. Promotes MEK and RAF phosphorylation and activity through assembly of an activated signaling complex. By itself, it has no demonstrated kinase activity.
Catalog Number: BOSSBS-3549R-FITC
UOM: 1 * 100 µl
Supplier: Bioss


Description: This gene encodes a kinetochore protein that functions aspart of the minichromosome instability-12 centromere complex. Theencoded protein is required for proper kinetochore assembly andprogression through the cell cycle. Alternative splicing results inmultiple transcript variants. [provided by RefSeq, Feb 2009].
Catalog Number: BOSSBS-7796R-CY3
UOM: 1 * 100 µl
Supplier: Bioss


Description: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
Catalog Number: BOSSBS-4690R-CY3
UOM: 1 * 100 µl
Supplier: Bioss


Description: Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 and SMC4. hCAP-D3 is a regulatory non-SMC subunit of the condensin II complex.
Catalog Number: BOSSBS-7734R-HRP
UOM: 1 * 100 µl
Supplier: Bioss


Description: Together with dynein may be involved in spindle assembly and cytokinesis.Tissue specificity:Ubiquitously expressed. Highly expressed in muscle and pancreas and detected at lower levels in brain.
Catalog Number: BOSSBS-7746R-CY3
UOM: 1 * 100 µl
Supplier: Bioss


Description: Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle.
Catalog Number: BOSSBS-4011R-A350
UOM: 1 * 100 µl
Supplier: Bioss


Description: Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa.
Catalog Number: BOSSBS-5020R-A555
UOM: 1 * 100 µl
Supplier: Bioss


Description: Together with dynein may be involved in spindle assembly and cytokinesis.Tissue specificity:Ubiquitously expressed. Highly expressed in muscle and pancreas and detected at lower levels in brain.
Catalog Number: BOSSBS-7746R-A647
UOM: 1 * 100 µl
Supplier: Bioss


Description: UQCRC2 is a component of the ubiquinol cytochrome c reductase complex (complex III), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex.
Catalog Number: BOSSBS-3973R-CY5
UOM: 1 * 100 µl
Supplier: Bioss


Description: UQCRC2 is a component of the ubiquinol cytochrome c reductase complex (complex III), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex.
Catalog Number: BOSSBS-3973R-A750
UOM: 1 * 100 µl
Supplier: Bioss


Description: This helmet assembly part securely attaches Peltor™ X-series earmuffs to Versaflo™ headtops M-series or Speedglas™ welding helmet 9100 MP, for effective hearing protection.
Catalog Number: MMMAPZ3AF
UOM: 1 * 1 KIT
Supplier: 3M


Description: Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.
Catalog Number: BOSSBS-5884R-CY7
UOM: 1 * 100 µl
Supplier: Bioss


Description: UQCRC2 is a component of the ubiquinol cytochrome c reductase complex (complex III), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex.
Catalog Number: BOSSBS-3973R-A647
UOM: 1 * 100 µl
Supplier: Bioss


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