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Product Image-613-5711

Accessories for VWR® Pipette Controllers

Supplier: VWR Collection
Description: Controller, pipette

Image Unavailable-BOSSBS-11072R-A647

Anti-ASTN2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-11072R-A647)
Supplier: Bioss
Description: Neuronal migration of the central nervous system is a specialized form of cell motility that takes place in the laminar structure of the cortical regions of brain. Astrotactin is a neuronal cell surface protein expressed on postmitotic neuronal precursors in the cerebellum, hippocampus, cerebrum, and olfactory bulb. Astrotactin 2 is a paralog of Astrotactin. Astrotactin mediates neuron-astroglial interactions and is also implicated in synaptic development as well as many other neuronal activities. Astrotactin has three epidermal growth factor repeat domains and two fibronectin type III repeat domains. The human Astrotactin gene shows extensive homology to the mouse Astrotactin gene. Mutations in the Astrotactin gene are linked to neuronal migration defects in both species.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10392R-A488

Anti-SYNGAP Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-10392R-A488)
Supplier: Bioss
Description: The PSD-95/SAP 90 family of proteins, which are known to bind to and cluster various membrane proteins, are involved in the organization of synaptic structure. SynGAP (for synaptic GTPase activating protein), a novel synaptic RasGAP, is a brain-specific protein abundant in the cortex, hippocampus and olfactory bulb. SynGAP interacts with all three PDZ domains within PSD-95/ SAP 90 proteins. It represents one of three classes of mammalian RasGAPs and is specifically localized to excitatory synapses possessing NMDA receptors. SynGAP may be involved in the regulation of BDNF as well as Ras signaling. Its activity is inhibited by phosphorylation by CaMKII, which could result in the activation of the MAP kinase pathway.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15047R-FITC

Anti-C1orf187 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-15047R-FITC)
Supplier: Bioss
Description: C1orf187, also known as Draxin, Dorsal repulsive axon guidance protein and Neucrin, is a 349 amino acid secreted protein that is required of the development of the spinal cord and forebrain commissures. C1orf187 acts as a chemorepulsive guidance protein and directs commissural axons during development by repelling neurite outgrowth from the spinal cord. During development, C1orf187 modulates neural crest migration by reducing the polarization of these cells, leading to reduced velocity of migration and increased frequency of changing direction, leading to a net decrease in migrational distance. It acts as an antagonist of the Wnt signaling pathway by inhibiting the stabilization of cytosolic _-catenin via its interaction with LRP6. C1orf187 inhibits outgrowth from the olfactory bulb and likely contributes to the formation of the lateral olfactory tract.
UOM: 1 * 100 µl
Product Image-552-0283

TLC Accessories

Catalog Number: (552-0283)
Supplier: MACHEREY-NAGEL
Description: Glass laboratory sprayer with rubber bulb
UOM: 1 * 1 items
Product Image-612-6117

VWR® Pipette Stand, Rotary

Supplier: VWR Collection
Description: This carousel pipette stand, made from ABS, can hold up to eight single-channel, four multi-channel, or a combination of both pipettes.

Product Image-UVPA19-0126-01

Accessories for UV inspection lamp, B-100AP

Supplier: UVP ULTRA VIOLET PRODUCTS
Description: Lamp visor

Image Unavailable-JENC267-304

Pipette controller, Biohit Midi Pro

Supplier: VWR Collection
Description: Pipette controller, Pro

Product Image-612-7287

Accessories for VWR® Pipette Filler, White/Blue

Supplier: VWR Collection
Description: Pipette controller, VWR®

Image Unavailable-BOSSBS-2743R-CY7

Anti-SLIT2 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-2743R-CY7)
Supplier: Bioss
Description: Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. In vitro, silences the attractive effect of NTN1 but not its growth-stimulatory effect and silencing requires the formation of a ROBO1-DCC complex. May be implicated in spinal chord midline post-crossing axon repulsion. In vitro, only commissural axons that crossed the midline responded to SLIT2. In the developing visual system appears to function as repellent for retinal ganglion axons by providing a repulsion that directs these axons along their appropriate paths prior to, and after passage through, the optic chiasm. In vitro, collapses and repels retinal ganglion cell growth cones. Seems to play a role in branching and arborization of CNS sensory axons, and in neuronal cell migration. In vitro, Slit homolog 2 protein N-product, but not Slit homolog 2 protein C-product, repels olfactory bulb (OB) but not dorsal root ganglia (DRG) axons, induces OB growth cones collapse and induces branching of DRG axons. Seems to be involved in regulating leukocyte migration.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2743R-A350

Anti-SLIT2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-2743R-A350)
Supplier: Bioss
Description: Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. In vitro, silences the attractive effect of NTN1 but not its growth-stimulatory effect and silencing requires the formation of a ROBO1-DCC complex. May be implicated in spinal chord midline post-crossing axon repulsion. In vitro, only commissural axons that crossed the midline responded to SLIT2. In the developing visual system appears to function as repellent for retinal ganglion axons by providing a repulsion that directs these axons along their appropriate paths prior to, and after passage through, the optic chiasm. In vitro, collapses and repels retinal ganglion cell growth cones. Seems to play a role in branching and arborization of CNS sensory axons, and in neuronal cell migration. In vitro, Slit homolog 2 protein N-product, but not Slit homolog 2 protein C-product, repels olfactory bulb (OB) but not dorsal root ganglia (DRG) axons, induces OB growth cones collapse and induces branching of DRG axons. Seems to be involved in regulating leukocyte migration.
UOM: 1 * 100 µl
Product Image-613-5747

VWR® Pipette Charging Stand, Rotary

Catalog Number: (613-5747)
Supplier: VWR Collection
Description: This power carousel is a comfortable charging solution for up to five electronic pipettes.
UOM: 1 * 1 items
Product Image-613-5472

VWR® Stands for VWR® Pipettes

Supplier: VWR Collection
Description: Pipette stands for VWR® mechanical pipettes.

Product Image-613-5428

VWR® Stand for Electronic Pipettes

Catalog Number: (613-5428)
Supplier: VWR Collection
Description: Charging stand adapter for carousel pipette stand, VWR®, For: Electronic pipettes
UOM: 1 * 1 items
Product Image-613-7101

VWR®, Macro Pipette Tips

Supplier: VWR Collection
Description: Improved accuracy over serological pipettes.

Image Unavailable-BOSSBS-11751R-A647

Anti-PQBP1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-11751R-A647)
Supplier: Bioss
Description: Polyglutamine(Q) tract binding protein-1 (PQBP-1) is a transcription repressor that associates with polyglutamine tract-containing transcription regulators and causative genes for neurodegenerative disorders. Hepta- and di-amino acid repeat sequences rich in polar residues are essential for PQBP-1 to interact with polyglutamine tract-containing proteins (i.e. huntingtin, androgen receptor and Brain-2). PQBP-1 contains a WWP/WW domain that binds proline-rich motifs and a C2 domain that can influence Ca2+-dependent phospholipid signaling. PQBP-1 localizes to the nucleus and is present in neurons throughout the brain, with abundant levels in hippocampus, cerebellar cortex and olfactory bulb. The human PQBP-1 gene maps to chromosome Xp11.23.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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