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Image Unavailable-BOSSBS-15047R-CY7

Anti-C1orf187 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-15047R-CY7)
Supplier: Bioss
Description: C1orf187, also known as Draxin, Dorsal repulsive axon guidance protein and Neucrin, is a 349 amino acid secreted protein that is required of the development of the spinal cord and forebrain commissures. C1orf187 acts as a chemorepulsive guidance protein and directs commissural axons during development by repelling neurite outgrowth from the spinal cord. During development, C1orf187 modulates neural crest migration by reducing the polarization of these cells, leading to reduced velocity of migration and increased frequency of changing direction, leading to a net decrease in migrational distance. It acts as an antagonist of the Wnt signaling pathway by inhibiting the stabilization of cytosolic _-catenin via its interaction with LRP6. C1orf187 inhibits outgrowth from the olfactory bulb and likely contributes to the formation of the lateral olfactory tract.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2743R-HRP

Anti-SLIT2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-2743R-HRP)
Supplier: Bioss
Description: Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. In vitro, silences the attractive effect of NTN1 but not its growth-stimulatory effect and silencing requires the formation of a ROBO1-DCC complex. May be implicated in spinal chord midline post-crossing axon repulsion. In vitro, only commissural axons that crossed the midline responded to SLIT2. In the developing visual system appears to function as repellent for retinal ganglion axons by providing a repulsion that directs these axons along their appropriate paths prior to, and after passage through, the optic chiasm. In vitro, collapses and repels retinal ganglion cell growth cones. Seems to play a role in branching and arborization of CNS sensory axons, and in neuronal cell migration. In vitro, Slit homolog 2 protein N-product, but not Slit homolog 2 protein C-product, repels olfactory bulb (OB) but not dorsal root ganglia (DRG) axons, induces OB growth cones collapse and induces branching of DRG axons. Seems to be involved in regulating leukocyte migration.
UOM: 1 * 100 µl
Product Image-612-5779

VWR® Pipette Holder, Wall Mountable

Supplier: VWR Collection
Description: This universal wall mount made from robust ABS holds two single channel, or two multi-channel pipettes, or a combination of both.

Product Image-613-5747

VWR® Pipette Charging Stand, Rotary

Catalog Number: (613-5747)
Supplier: VWR Collection
Description: This power carousel is a comfortable charging solution for up to five electronic pipettes.
UOM: 1 * 1 items
Image Unavailable-BOSSBS-10392R-A647

Anti-SYNGAP Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-10392R-A647)
Supplier: Bioss
Description: The PSD-95/SAP 90 family of proteins, which are known to bind to and cluster various membrane proteins, are involved in the organization of synaptic structure. SynGAP (for synaptic GTPase activating protein), a novel synaptic RasGAP, is a brain-specific protein abundant in the cortex, hippocampus and olfactory bulb. SynGAP interacts with all three PDZ domains within PSD-95/ SAP 90 proteins. It represents one of three classes of mammalian RasGAPs and is specifically localized to excitatory synapses possessing NMDA receptors. SynGAP may be involved in the regulation of BDNF as well as Ras signaling. Its activity is inhibited by phosphorylation by CaMKII, which could result in the activation of the MAP kinase pathway.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15047R-CY5

Anti-C1orf187 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-15047R-CY5)
Supplier: Bioss
Description: C1orf187, also known as Draxin, Dorsal repulsive axon guidance protein and Neucrin, is a 349 amino acid secreted protein that is required of the development of the spinal cord and forebrain commissures. C1orf187 acts as a chemorepulsive guidance protein and directs commissural axons during development by repelling neurite outgrowth from the spinal cord. During development, C1orf187 modulates neural crest migration by reducing the polarization of these cells, leading to reduced velocity of migration and increased frequency of changing direction, leading to a net decrease in migrational distance. It acts as an antagonist of the Wnt signaling pathway by inhibiting the stabilization of cytosolic _-catenin via its interaction with LRP6. C1orf187 inhibits outgrowth from the olfactory bulb and likely contributes to the formation of the lateral olfactory tract.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11861R

Anti-KALRN Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-11861R)
Supplier: Bioss
Description: HAP1 (huntingtin-associated protein 1) binds to huntingtin (1). Huntingtin is a protein that contains a polyglutamine region and when the number of glutamine repeats exceeds 35, the gene encodes a version of huntingtin that leads to Huntington’s disease (HD) (2,3). The ability of HAP1 to bind to huntingtin is enhanced by an expanded polyglutamine repeat region (1). HAP1 shows neuronal localization and moves with huntingtin in nerve fibers (4,5). HAP1 is primarily expressed in brain tissue, with greater expression in the olfactory bulb and brain stem (1). Mouse HAP1 is localized to membrane-bound organelles including large endosomes, tubulovesicular structures and budding vesicles in neurons (6). Duo, also designated huntingtin-associated protein interacting protein or HAPIP, binds Huntingtin-associated protein 1 (HAP1) and may have a role in vesicle trafficking and cytoskeletal function.
UOM: 1 * 100 µl
Product Image-MOTI1101002400431

Accessories for SMZ-171

Catalog Number: (MOTI1101002400431)
Supplier: MOTIC
Description: Accessory for microscopes, For: SMZ-171, Halogen bulb, 21 V/150 W
UOM: 1 * 1 items
Product Image-HECH40850002

Pressure bulbs

Supplier: GLASWARENFABRIK KARL HECHT
Description: simple: with 2 valves – made of soft PVC (cadmium-free)
double: with valve - made of soft PVC (cadmium-free), ball in the net made of latex

Product Image-BOEI234100-2

UV crosslinker, AH

Catalog Number: (BOEI234100-2)
Supplier: BOEKEL SCIENTIFIC
Description: Whether crosslinking DNA or RNA, conducting Northern, Southern dot or slot blot analysis or UV curing, the UV Crosslinker AH provides a safe, time-efficient solution with a controlled amount of ultraviolet radiation. The UV Crosslinker AH incorporates an adjustable height feature which gives true-to-life readings by keeping samples on the base of the chamber, at the same distance from the bulbs as the fixed UV sensor. Instead of building up samples to get them closer to the bulbs, it is possible simply to adjust the bulbs to get them closer to the sample. The microprocessor detects the exact energy of the bulbs and compensates accordingly.
UOM: 1 * 1 items
Product Image-613-0582

VWR®, Pipette Tips for Rainin® LTS® Pipettes

Catalog Number: (613-0582)
Supplier: VWR Collection
Description: These VWR® pipette tips are made of clear, pre-tested PP resin and fit Rainin® LTS® pipettes.
UOM: 1 * 576 items

Environmentally Preferable


Image Unavailable-BOSSBS-2743R-CY5.5

Anti-SLIT2 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-2743R-CY5.5)
Supplier: Bioss
Description: Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. In vitro, silences the attractive effect of NTN1 but not its growth-stimulatory effect and silencing requires the formation of a ROBO1-DCC complex. May be implicated in spinal chord midline post-crossing axon repulsion. In vitro, only commissural axons that crossed the midline responded to SLIT2. In the developing visual system appears to function as repellent for retinal ganglion axons by providing a repulsion that directs these axons along their appropriate paths prior to, and after passage through, the optic chiasm. In vitro, collapses and repels retinal ganglion cell growth cones. Seems to play a role in branching and arborization of CNS sensory axons, and in neuronal cell migration. In vitro, Slit homolog 2 protein N-product, but not Slit homolog 2 protein C-product, repels olfactory bulb (OB) but not dorsal root ganglia (DRG) axons, induces OB growth cones collapse and induces branching of DRG axons. Seems to be involved in regulating leukocyte migration.
UOM: 1 * 100 µl
Product Image-613-7101

VWR®, Macro Pipette Tips

Supplier: VWR Collection
Description: Improved accuracy over serological pipettes.

Product Image-710-1021

VWR® SP100 Automatic Straw Pipette, Fixed Volume

Catalog Number: (710-1021)
Supplier: VWR Collection
Description: Air displacement pipette with two pre-calibrated steps allows subsequent pipetting of 1 and 0,1 ml of the same liquid. Ideal alternative to graduated glass pipettes when performing serial 1:10 dilutions in bacteriology.
UOM: 1 * 1 items
Image Unavailable-BOSSBS-2743R-A750

Anti-SLIT2/Slil3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-2743R-A750)
Supplier: Bioss
Description: Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. In vitro, silences the attractive effect of NTN1 but not its growth-stimulatory effect and silencing requires the formation of a ROBO1-DCC complex. May be implicated in spinal chord midline post-crossing axon repulsion. In vitro, only commissural axons that crossed the midline responded to SLIT2. In the developing visual system appears to function as repellent for retinal ganglion axons by providing a repulsion that directs these axons along their appropriate paths prior to, and after passage through, the optic chiasm. In vitro, collapses and repels retinal ganglion cell growth cones. Seems to play a role in branching and arborization of CNS sensory axons, and in neuronal cell migration. In vitro, Slit homolog 2 protein N-product, but not Slit homolog 2 protein C-product, repels olfactory bulb (OB) but not dorsal root ganglia (DRG) axons, induces OB growth cones collapse and induces branching of DRG axons. Seems to be involved in regulating leukocyte migration.
UOM: 1 * 100 µl
Product Image-612-3705

VWR® Serological Pipette, Standard Line

Supplier: VWR Collection
Description: 100% high-clarity polystyrene, graduated, sterile.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
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