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Image Unavailable-BOSSBS-2743R-HRP

Anti-SLIT2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-2743R-HRP)
Supplier: Bioss
Description: Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. In vitro, silences the attractive effect of NTN1 but not its growth-stimulatory effect and silencing requires the formation of a ROBO1-DCC complex. May be implicated in spinal chord midline post-crossing axon repulsion. In vitro, only commissural axons that crossed the midline responded to SLIT2. In the developing visual system appears to function as repellent for retinal ganglion axons by providing a repulsion that directs these axons along their appropriate paths prior to, and after passage through, the optic chiasm. In vitro, collapses and repels retinal ganglion cell growth cones. Seems to play a role in branching and arborization of CNS sensory axons, and in neuronal cell migration. In vitro, Slit homolog 2 protein N-product, but not Slit homolog 2 protein C-product, repels olfactory bulb (OB) but not dorsal root ganglia (DRG) axons, induces OB growth cones collapse and induces branching of DRG axons. Seems to be involved in regulating leukocyte migration.
UOM: 1 * 100 µl
Product Image-612-5885

VWR®, Aspirating Pipettes

Supplier: VWR Collection
Description: PS pipettes, non plugged, non graduated, disposable, sterile.

Image Unavailable-BOSSBS-2743R-CY5

Anti-SLIT2 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-2743R-CY5)
Supplier: Bioss
Description: Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. In vitro, silences the attractive effect of NTN1 but not its growth-stimulatory effect and silencing requires the formation of a ROBO1-DCC complex. May be implicated in spinal chord midline post-crossing axon repulsion. In vitro, only commissural axons that crossed the midline responded to SLIT2. In the developing visual system appears to function as repellent for retinal ganglion axons by providing a repulsion that directs these axons along their appropriate paths prior to, and after passage through, the optic chiasm. In vitro, collapses and repels retinal ganglion cell growth cones. Seems to play a role in branching and arborization of CNS sensory axons, and in neuronal cell migration. In vitro, Slit homolog 2 protein N-product, but not Slit homolog 2 protein C-product, repels olfactory bulb (OB) but not dorsal root ganglia (DRG) axons, induces OB growth cones collapse and induces branching of DRG axons. Seems to be involved in regulating leukocyte migration.
UOM: 1 * 100 µl
Product Image-613-6440

VWR®, Universal Pipette Tips

Supplier: VWR Collection
Description: VWR® Universal low retention pipette tips repel liquid by creating a hydrophobic surface on the inside of the tip increasing your accuracy and data quality.

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Image Unavailable-BOSSBS-11072R-A680

Anti-ASTN2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-11072R-A680)
Supplier: Bioss
Description: Neuronal migration of the central nervous system is a specialised form of cell motility that takes place in the laminar structure of the cortical regions of brain. Astrotactin is a neuronal cell surface protein expressed on postmitotic neuronal precursors in the cerebellum, hippocampus, cerebrum, and olfactory bulb. Astrotactin 2 is a paralog of Astrotactin. Astrotactin mediates neuron-astroglial interactions and is also implicated in synaptic development as well as many other neuronal activities. Astrotactin has three epidermal growth factor repeat domains and two fibronectin type III repeat domains. The human Astrotactin gene shows extensive homology to the mouse Astrotactin gene. Mutations in the Astrotactin gene are linked to neuronal migration defects in both species.
UOM: 1 * 100 µl
Product Image-612-3701

VWR® Serological Pipette, Standard Line

Supplier: VWR Collection
Description: 100% high-clarity polystyrene, graduated, sterile.

Certificates

Image Unavailable-BOSSBS-11072R-HRP

Anti-ASTN2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-11072R-HRP)
Supplier: Bioss
Description: Neuronal migration of the central nervous system is a specialized form of cell motility that takes place in the laminar structure of the cortical regions of brain. Astrotactin is a neuronal cell surface protein expressed on postmitotic neuronal precursors in the cerebellum, hippocampus, cerebrum, and olfactory bulb. Astrotactin 2 is a paralog of Astrotactin. Astrotactin mediates neuron-astroglial interactions and is also implicated in synaptic development as well as many other neuronal activities. Astrotactin has three epidermal growth factor repeat domains and two fibronectin type III repeat domains. The human Astrotactin gene shows extensive homology to the mouse Astrotactin gene. Mutations in the Astrotactin gene are linked to neuronal migration defects in both species.
UOM: 1 * 100 µl
Product Image-466-0635

Accessories for vacuum drying chambers, VD and VDL series

Catalog Number: (466-0635)
Supplier: Binder
Description: Interior lighting -, with 15 W light bulb, For: Vacuum drying chambers, VD and VDL series
UOM: 1 * 1 items
Product Image-612-4122

VWR®, Graduated Pipettes, Type 3, Class B

Supplier: VWR Collection
Description: Borosilicate 9.1 glass.

Image Unavailable-BOSSBS-15047R-A647

Anti-C1orf187 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-15047R-A647)
Supplier: Bioss
Description: C1orf187, also known as Draxin, Dorsal repulsive axon guidance protein and Neucrin, is a 349 amino acid secreted protein that is required of the development of the spinal cord and forebrain commissures. C1orf187 acts as a chemorepulsive guidance protein and directs commissural axons during development by repelling neurite outgrowth from the spinal cord. During development, C1orf187 modulates neural crest migration by reducing the polarization of these cells, leading to reduced velocity of migration and increased frequency of changing direction, leading to a net decrease in migrational distance. It acts as an antagonist of the Wnt signaling pathway by inhibiting the stabilization of cytosolic _-catenin via its interaction with LRP6. C1orf187 inhibits outgrowth from the olfactory bulb and likely contributes to the formation of the lateral olfactory tract.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11861R-CY7

Anti-KALRN Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-11861R-CY7)
Supplier: Bioss
Description: HAP1 (huntingtin-associated protein 1) binds to huntingtin (1). Huntingtin is a protein that contains a polyglutamine region and when the number of glutamine repeats exceeds 35, the gene encodes a version of huntingtin that leads to Huntington’s disease (HD) (2,3). The ability of HAP1 to bind to huntingtin is enhanced by an expanded polyglutamine repeat region (1). HAP1 shows neuronal localization and moves with huntingtin in nerve fibers (4,5). HAP1 is primarily expressed in brain tissue, with greater expression in the olfactory bulb and brain stem (1). Mouse HAP1 is localized to membrane-bound organelles including large endosomes, tubulovesicular structures and budding vesicles in neurons (6). Duo, also designated huntingtin-associated protein interacting protein or HAPIP, binds Huntingtin-associated protein 1 (HAP1) and may have a role in vesicle trafficking and cytoskeletal function.
UOM: 1 * 100 µl
Product Image-612-3850

VWR®, Pasteur Pipettes

Supplier: VWR Collection
Description: Soda-lime glass, disposable.

Certificates

Product Image-612-7179

VWR® Pipette Controller

Catalog Number: (612-7179)
Supplier: VWR Collection
Description: The VWR® pipette controller is a compact and portable device that features multiple user-selectable modes and speeds to perform a wide range of liquid handling applications. Each device is supplied with a 3-year warranty.
UOM: 1 * 1 items
Product Image-614-2029

Accessories for butyrometers

Catalog Number: (614-2029)
Supplier: GERBER FUNKE
Description: Stopper, rubber, for sealing the bulbs of all weighing method butyrometers
UOM: 1 * 100 items
Product Image-613-2169

VWR® Stepper Pro, Repetitive Pipette

Catalog Number: (613-2169)
Supplier: VWR Collection
Description: This pipette is designed for the dispensing of contaminated fluids and volatile liquids. The acceptance of dispenser tips with plunger helps to avoid contamination by ascending aerosols in the tip guaranteeing long-term, secure use.
UOM: 1 * 1 items

Environmentally Preferable


Product Image-613-0964

VWR® Stepper Repetitive Pipette

Catalog Number: (613-0964)
Supplier: VWR Collection
Description: The Stepper, in combination with VWR® dispenser tips, is a proven system solution for the complete range of dispensing volumes from 1 to 5000 μl.
UOM: 1 * 1 items

Environmentally Preferable


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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