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Product Image-EDVO150

Experimentation kits, survey of protein diversity (polyacrylamide-based)

Catalog Number: (EDVO150)
Supplier: EDVOTEK
Description: For learning about the diversity of proteins by studying the electrophoretic profiles of various sources. Students separate proteins from bacterial, plant, serum, and milk proteins alongside a standard protein marker.
UOM: 1 * 1 items
Product Image-EDVO123

Nucleic acid testing for COVID-19

Catalog Number: (EDVO123)
Supplier: EDVOTEK
Description: Hands-on simulation of molecular testing for COVID-19.
UOM: 1 * 1 KIT
Image Unavailable-BOSSBS-13390R-A680

Anti-GLUD2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-13390R-A680)
Supplier: Bioss
Description: GLUD2 is both mitochondrial matrix enzymes belonging to the Glu/Leu/Phe/Val dehydrogenases family. Exisiting as homohexamers, GLUD1 catalyzes the oxidative deamination of glutamate to ?ketoglutarate and ammonia while GLUD2 is involved in the recycling of glutamate during neurotransmission. GLUD1 is critical for regulating amino acid induced insulin secretion and is allosterically activated by ADP and inhibited by GTP and ATP. Mutations in the gene encoding GLUD1 causes hyperinsulinism-hyperammonemia syndrome (HHS), which is an inherited condition characterized by high insulin and ammonia levels in the blood. GLUD1 may also be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. GLUD2 is expressed in testis and retina, with lower levels found in brain.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0175R-A750

Anti-TrkB Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-0175R-A750)
Supplier: Bioss
Description: Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4. Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2. Upon ligand-binding, undergoes homodimerisation, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades. Through SHC1, FRS2, SH2B1, SH2B2 activates the GRB2-Ras-MAPK cascade that regulates for instance neuronal differentiation including neurite outgrowth. Through the same effectors controls the Ras-PI3 kinase-AKT1 signaling cascade that mainly regulates growth and survival. Through PLCG1 and the downstream protein kinase C-regulated pathways controls synaptic plasticity. Thereby, plays a role in learning and memory by regulating both short term synaptic function and long-term potentiation. PLCG1 also leads to NF-Kappa-B activation and the transcription of genes involved in cell survival. Hence, it is able to suppress anoikis, the apoptosis resulting from loss of cell-matrix interactions. May also play a role in neutrophin-dependent calcium signaling in glial cells and mediate communication between neurons and glia.
UOM: 1 * 100 µl
Product Image-EDVOS-70

Experimentation kits, how does a doctor test for AIDS?

Catalog Number: (EDVOS-70)
Supplier: EDVOTEK
Description: The body defends itself from attack by infectious agents like bacteria and viruses by producing antibodies. Enzyme linked immunosorbent assays (ELISA) test for antibodies present in the blood, which indicate infection. In this experiment, students perform a simulated ELISA test to identify infected samples and compare them to control samples.
UOM: 1 * 1 items

MSDS


Product Image-EDVO957

Experimentation kits, DNA damage and repair

Catalog Number: (EDVO957)
Supplier: EDVOTEK
Description: According to the World Health Organisation, between two and three million cases of skin cancer occur globally every year. Many of these cases are caused by preventable damage to DNA by UV light. In this experiment, students expose plasmid DNA to shortwave UV light to simulate the effect of sunbathing. The DNA is then analysed by agarose gel electrophoresis to observe the damage.
UOM: 1 * 1 KIT
Image Unavailable-BOSSBS-11528R-CY3

Anti-GALR3 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-11528R-CY3)
Supplier: Bioss
Description: GALR3 a 368 and 370 amino acid protein in human and rat, respectively, belongs to a family of G protein-coupled receptors that bind the neuropeptide galanin, which is distributed throughout the central and peripheral nervous system, the pituitary gland, the gastrointestinal tract and in the endocrine and exocrine pancreas. GALR3 mRNA is widely distributed, but expressed at low abundance. In human, GALR3 mRNA is highly expressed in the hypothalamus, pituitary and testis, and is expressed to a lesser extent in adrenal gland and pancreas. Rat and human GALR3 co-express with potassium channel subunits GIRK1 and GIRK4. Like GALR1, GALR3 signaling pathways lead to the inhibition of adenylate cyclase and to the activation of potassium channels, which are linked to the regulation of neurotransmitter release. Binding of galanin to galanin receptors results in increased feeding, impaired learning, enhanced opiate analgesia and decreased opiate place preference.
UOM: 1 * 100 µl
Product Image-BINH1003080

Diffraction/transmission gratings

Supplier: 3B Scientific
Description: Transmission grating for spectroscopic examinations and for experiments on diffraction and interference. Suitable to resolve the sodium D lines.

Product Image-EDVOS-68

Experimentation kits, what is an epidemic and how does an infection spread?

Catalog Number: (EDVOS-68)
Supplier: EDVOTEK
Description: Infectious agents such as bacteria and viruses can spread rapidly through a population and cause widespready disease and death. In this experiment, students use coloured solutions to simulate the spreading of a disease in the classroom.
UOM: 1 * 1 items
Product Image-EDVOS-46

STEM concepts, agarose gel electrophoresis

Catalog Number: (EDVOS-46)
Supplier: EDVOTEK
Description: Link important STEM concepts using Agarose Gel Electrophoresis.
UOM: 1 * 1 items
Product Image-EDVO135

Using CRISPR to treat cystic fibrosis

Catalog Number: (EDVO135)
Supplier: EDVOTEK
Description: Hands-on simulation of CRISPR-Cas9 to target and treat Cystic Fibrosis.
UOM: 1 * 1 KIT
Product Image-DIDAPOD010007

Screens for optical bench

Supplier: DIDALAB
Description: Educational Materials, Optics, Application: Physics, Translucent screen 20×20 cm, attached to a rod with Ø 10 mm

Product Image-HECH44286010

Electrolysis apparatus acc.Hoffmann

Supplier: GLASWARENFABRIK KARL HECHT
Description: According to Hoffmann, with two city dishes, 0 to 30 ml of grading graded 1/10 ml.

Product Image-765-1092

Radiometer

Catalog Number: (765-1092)
Supplier: MOLLER THERM
Description: Radiometer according to Crookés. Consists of a glass container on foot with low air pressure and needle-bearing spinner with four vertical mica discs. The discs are black on one side and shiny on the other. The discs thus absorb radiation differently. The higher temperature of the dark side means that the air molecules get greater kinetic energy in collision with the dark side of the discs than with their shiny side. The result is that the spinner starts to rotate.
UOM: 1 * 1 items
Image Unavailable-NEUB0500-10-33

Electrolysis apparatus according to Hoffmann

Supplier: NEUBERT VOLUME GLASSWAERE
Description: Electrolysis apparatus according to Hoffmann, made of borosilicate glass 3.3.

Product Image-EDVO118-C

Kits: cholesterol diagnostics, Ready-to-Load™

Supplier: EDVOTEK
Description: Genetic testing can be used to identify people with a genetic condition which caused them to have an elevated level of cholesterol and which can be fatal. Students can see how genetic testing is carried out and learn about DNA electrophoresis.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
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Dual use goods can only be delivered within the European Union.
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