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Catalog Number: (ABNODI0175)
Supplier: Abnova
Description: This protein protein interaction Antibody Pair set comes with two antibodies to detect the protein-protein interaction, one against the SPP1 protein, and the other against the F2 protein for use in Proximity Ligation Assay
UOM: 1 * 1 SET


Catalog Number: (ABNODI0176)
Supplier: Abnova
Description: This protein protein interaction Antibody Pair set comes with two antibodies to detect the protein-protein interaction, one against the MMP1 protein, and the other against the F2R protein for use in Proximity Ligation Assay
UOM: 1 * 1 SET


Catalog Number: (ABNODI0163)
Supplier: Abnova
Description: This protein protein interaction Antibody Pair set comes with two antibodies to detect the protein-protein interaction, one against the TGFA protein, and the other against the ERBB2 protein for use in Proximity Ligation Assay
UOM: 1 * 1 SET


Catalog Number: (ABNODI0493)
Supplier: Abnova
Description: This protein protein interaction Antibody Pair set comes with two antibodies to detect the protein-protein interaction, one against the MAPK13 protein, and the other against the MAP3K4 protein for use in Proximity Ligation Assay
UOM: 1 * 1 SET


Catalog Number: (ABNODI0613)
Supplier: Abnova
Description: This protein protein interaction Antibody Pair set comes with two antibodies to detect the protein-protein interaction, one against the BCR protein, and the other against the PIK3CG protein for use in Proximity Ligation Assay
UOM: 1 * 1 SET


Catalog Number: (ABNODI0486)
Supplier: Abnova
Description: This protein protein interaction Antibody Pair set comes with two antibodies to detect the protein-protein interaction, one against the MAPK12 protein, and the other against the DUSP1 protein for use in Proximity Ligation Assay
UOM: 1 * 1 SET


Catalog Number: (PRSI90-447)
Supplier: ProSci Inc.
Description: Programmed Death-1 (PD-1, CD279) is a type I transmembrane protein belonging to the CD28/CTLA-4 family of immunoreceptors that mediate signals for regulating immune responses. Members of the CD28/CTLA-4 family have been shown to either promote T cell activation (CD28 and ICOS) or downregulate T cell activation (CTLA-4 and PD-1). CD279 is expressed on activated T-cells, B-cells, myeloid cells and on a subset of thymocytes. In vitro, ligation of CD279 inhibits TCR-mediated T-cell proliferation and production of IL-1, IL-4, IL-10 and IFN-gamma. In addition, CD279 ligation also inhibits BCR mediated signallling. CD279 deficient mice have a defect in peripheral tolerance and spontaneously develop autoimmune diseases.
UOM: 1 * 100 µG


Catalog Number: (BOSSBS-10055R-HRP)
Supplier: Bioss
Description: Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage. Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor. Phosphorylates DAB2IP at 'Ser-728' in a TNF-alpha-dependent manner, and thereby activates the MAP3K5-JNK apoptotic cascade. Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules. Polyubiquitinated protein binds to IKBKG/NEMO, the regulatory subunit of the IKK complex, a critical event for NF-kappa-B activation. Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death. RIPK1 and RIPK3 association, in particular, forms a necrosis-inducing complex.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-5805R-A350)
Supplier: Bioss
Description: Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage. Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor. Phosphorylates DAB2IP at 'Ser-728' in a TNF-alpha-dependent manner, and thereby activates the MAP3K5-JNK apoptotic cascade. Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules. Polyubiquitinated protein binds to IKBKG/NEMO, the regulatory subunit of the IKK complex, a critical event for NF-kappa-B activation. Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death. RIPK1 and RIPK3 association, in particular, forms a necrosis-inducing complex.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-5805R-HRP)
Supplier: Bioss
Description: Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage. Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor. Phosphorylates DAB2IP at 'Ser-728' in a TNF-alpha-dependent manner, and thereby activates the MAP3K5-JNK apoptotic cascade. Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules. Polyubiquitinated protein binds to IKBKG/NEMO, the regulatory subunit of the IKK complex, a critical event for NF-kappa-B activation. Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death. RIPK1 and RIPK3 association, in particular, forms a necrosis-inducing complex.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-5805R-A647)
Supplier: Bioss
Description: Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage. Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor. Phosphorylates DAB2IP at 'Ser-728' in a TNF-alpha-dependent manner, and thereby activates the MAP3K5-JNK apoptotic cascade. Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules. Polyubiquitinated protein binds to IKBKG/NEMO, the regulatory subunit of the IKK complex, a critical event for NF-kappa-B activation. Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death. RIPK1 and RIPK3 association, in particular, forms a necrosis-inducing complex.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-5805R-CY5.5)
Supplier: Bioss
Description: Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage. Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor. Phosphorylates DAB2IP at 'Ser-728' in a TNF-alpha-dependent manner, and thereby activates the MAP3K5-JNK apoptotic cascade. Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules. Polyubiquitinated protein binds to IKBKG/NEMO, the regulatory subunit of the IKK complex, a critical event for NF-kappa-B activation. Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death. RIPK1 and RIPK3 association, in particular, forms a necrosis-inducing complex.
UOM: 1 * 100 µl


Catalog Number: (ABNODI0345)
Supplier: Abnova
Description: This protein protein interaction Antibody Pair set comes with two antibodies to detect the protein-protein interaction, one against the MAPK3 protein, and the other against the RPS6KA2 protein for use in Proximity Ligation Assay
UOM: 1 * 1 SET


Catalog Number: (ABNODI0140)
Supplier: Abnova
Description: This protein protein interaction Antibody Pair set comes with two antibodies to detect the protein-protein interaction, one against the JUP protein, and the other against the CTNNA1 protein for use in Proximity Ligation Assay
UOM: 1 * 1 SET


Catalog Number: (ABNODI0398)
Supplier: Abnova
Description: This protein protein interaction Antibody Pair set comes with two antibodies to detect the protein-protein interaction, one against the PTK2 protein, and the other against the YES1 protein for use in Proximity Ligation Assay
UOM: 1 * 1 SET


Catalog Number: (ABNODI0419)
Supplier: Abnova
Description: This protein protein interaction Antibody Pair set comes with two antibodies to detect the protein-protein interaction, one against the EPAS1 protein, and the other against the SMAD3 protein for use in Proximity Ligation Assay
UOM: 1 * 1 SET


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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