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Product Image-ICNA0290545401

AIN-76 vitamin mixture, MP Biomedicals

Catalog Number: (ICNA0290545401)
Supplier: MP Biomedicals
Description: AIN-76 vitamin mixture is a basic component of animal diet for mice and rats colonies in the research lab.
UOM: 1 * 1 kg
Image Unavailable-BOSSBS-1599R-A488

Anti-Calpain 2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-1599R-A488)
Supplier: Bioss
Description: Calpain, and m calpain, also known as Calpain 2, are intracellular, calcium dependent cysteine proteases. Mu calpain has a micromolar sensitivity (thus the mu) as compared to the millimolar calcium sensitivity of m calpain. Both Calpains 1 and 2 are composed of an 80 kD subunit and a 30 kD subunit. Whereas the 30 kDa subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca++ requirements that are suggested by their names. The calpains have papain like activity, thus the pain nomenclature. Both Calpain 1 and Calpain 2 are ubiquitously expressed, and are countered by the endogenous calpain inhibitor, calpastatin. Other calpain family members (calpain 94, ncl2, ncl3, etc) have more limited tissue distribution, and perhaps different functions. The calpain family members consist of a common small subunit (Calpain 4), and a large variable subunit. It is not clear that all calpains contain a small subunit. Domains in the large subunit include the amino terminal domain I, the proteinase domain II, domain III, and the EF hand domain IV. The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1599R-CY5.5

Anti-Calpain 2 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-1599R-CY5.5)
Supplier: Bioss
Description: Calpain, and m calpain, also known as Calpain 2, are intracellular, calcium dependent cysteine proteases. Mu calpain has a micromolar sensitivity (thus the mu) as compared to the millimolar calcium sensitivity of m calpain. Both Calpains 1 and 2 are composed of an 80 kD subunit and a 30 kD subunit. Whereas the 30 kDa subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca++ requirements that are suggested by their names. The calpains have papain like activity, thus the pain nomenclature. Both Calpain 1 and Calpain 2 are ubiquitously expressed, and are countered by the endogenous calpain inhibitor, calpastatin. Other calpain family members (calpain 94, ncl2, ncl3, etc) have more limited tissue distribution, and perhaps different functions. The calpain family members consist of a common small subunit (Calpain 4), and a large variable subunit. It is not clear that all calpains contain a small subunit. Domains in the large subunit include the amino terminal domain I, the proteinase domain II, domain III, and the EF hand domain IV. The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1599R-CY7

Anti-Calpain 2 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-1599R-CY7)
Supplier: Bioss
Description: Calpain, and m calpain, also known as Calpain 2, are intracellular, calcium dependent cysteine proteases. Mu calpain has a micromolar sensitivity (thus the mu) as compared to the millimolar calcium sensitivity of m calpain. Both Calpains 1 and 2 are composed of an 80 kD subunit and a 30 kD subunit. Whereas the 30 kDa subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca++ requirements that are suggested by their names. The calpains have papain like activity, thus the pain nomenclature. Both Calpain 1 and Calpain 2 are ubiquitously expressed, and are countered by the endogenous calpain inhibitor, calpastatin. Other calpain family members (calpain 94, ncl2, ncl3, etc) have more limited tissue distribution, and perhaps different functions. The calpain family members consist of a common small subunit (Calpain 4), and a large variable subunit. It is not clear that all calpains contain a small subunit. Domains in the large subunit include the amino terminal domain I, the proteinase domain II, domain III, and the EF hand domain IV. The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1515R

Anti-Pan-ras Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-1515R)
Supplier: Bioss
Description: RAS superfamily comprises around 50 related genes encoding GTP-binding domain (G-proteins) involved in signal transduction. The main genes are HRAS, NRAS and KRAS. Ras proteins are membrane-bound GTPases. The inactive form is GDP-bound. They are activated by ligand-binding receptor tyrosine kinases such as EGFR, PDGFR, colony-stimulating factor and fibroblast growth factor. These kinases transiently convert RAS-GDP to RAS-GTP, the active form of RAS. Single amino acid substitutions can activate RAS making it highly oncogenic. Such mutations generally reduce the GTPase activity of RAS, prolonging it in its active GTP-bound form. The consequence of this is sustained activation of the RAF1-MAPK signalling pathway. RAS mutations are found in 10-15% of tumours. A high incidence of RAS mutations is found in pancreatic cancers.
UOM: 1 * 100 µl
Product Image-PRSI56-594

Anti-SLC9A2 Rabbit Polyclonal Antibody

Catalog Number: (PRSI56-594)
Supplier: ProSci Inc.
Description: SLC9A2 is involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Seems to play an important role in colonic sodium absorption.
UOM: 1 * 400 µl
Product Image-LIED796C

Biology prepared microscope slides, school set D

Catalog Number: (LIED796C)
Supplier: LIEDER JOHANNES
Description: The slides are arranged and compiled, so that each enlarges the subject line of the proceeding one.
UOM: 1 * 1 items
Image Unavailable-ICNA0296009801

Vitamin mixture, AIN-76-A, MP Biomedicals

Catalog Number: (ICNA0296009801)
Supplier: MP Biomedicals
Description: Basic component of animal diet especially for maintaining mice and rats colonies in the research laboratory.
UOM: 1 * 1 kg
Product Image-STMC02300

Agar Leukocyte Conditioned Medium

Catalog Number: (STMC02300)
Supplier: STEMCELL Technologies
Description: Source of colony-stimulating factors for assays of human hematopoietic progenitor cells.
UOM: 1 * 25 mL
Product Image-SHBT400-12-1MG

Pig Recombinant GM-CSF (from E. coli)

Supplier: Shenandoah Biotechnology
Description: Granulocyte-macrophage colony-stimulating factor (GM-CSF) is hematopoietic growth factor produced by endothelial cells, monocytes, fibroblasts, and T cells. GM-CSF stimulates the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells. GM-CSF promotes immune system development and regulates neutrophil function during infection.

Image Unavailable-PRSI92-587

Mouse recombinant FLT3 ligand

Catalog Number: (PRSI92-587)
Supplier: ProSci Inc.
Description: Fms-related tyrosine kinase 3 ligand(Flt3L) is a single-pass type I membrane protein and consists of 232 amino acids. Flt3L is a hematopoietic four helical bundle cytokine, structurally homologous to stem cell factor and colony stimulating factor. Flt3L synergises well with a number of other colony stimulating factors and interleukins. Flt3L stimulates the proliferation and differentiation of various blood cell progentiors by activating FLT3.
UOM: 1 * 50 µG
Product Image-PIER75768

Yeast β-galactosidase assay kit, Pierce™

Catalog Number: (PIER75768)
Supplier: Thermo Fisher Scientific
Description: Yeast β-Galactosidase Assay Kit is specially formulated for yeast cells and ideal for identifying protein interactions<i> in vivo</i> using two-hybrid systems.
UOM: 1 * 1 KIT
Product Image-SHBT300-03-1MG

Rat Recombinant GM-CSF (from E. coli)

Supplier: Shenandoah Biotechnology
Description: Granulocyte-macrophage colony-stimulating factor (GM-CSF) is hematopoietic growth factor produced by endothelial cells, monocytes, fibroblasts, and T cells. GM-CSF stimulates the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells. GM-CSF promotes immune system development and regulates neutrophil function during infection.

Product Image-611-2637

Printer and accessories for balances

Supplier: Sartorius Balances
Description: The Sartorius printer YDP20-0CE has date, time statistics and transaction counter functions and is suitable for use in legal metrology. These capabilities when attached to balances with built in GLP functions, allow GLP compliant printouts including operator details and spaces for signatures.

Product Image-SHBT300-33-100UG

Rat Recombinant M-CSF (from E. coli)

Supplier: Shenandoah Biotechnology
Description: Macrophage colony stimulating factor (M-CSF) is a hematopoietic growth factor that is widely produced by a variety of cells. M-CSF stimulates the proliferation and differentiation of hematopoietic stem cells into monocyte and macrophage cell types. M-CSF also acts through the colony stimulating factor 1 receptor (CSF1R) to modulate processes involved in immunology, bone metabolism, fertility, and pregnancy.

Product Image-BSBTPB9563

Anti-G-CSF Rabbit Polyclonal Antibody

Catalog Number: (BSBTPB9563)
Supplier: Boster Bio
Description: Rabbit IgG polyclonal antibody for Granulocyte colony-stimulating factor(CSF3) detection. Tested with WB, ELISA in Human.
UOM: 1 * 100 µG
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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