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Image Unavailable-BOSSBS-5973R-A488

Anti-SIRT7 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-5973R-A488)
Supplier: Bioss
Description: NAD-dependent protein deacetylase that specifically mediates deacetylation of histone H3 at 'Lys-18' (H3K18Ac). In contrast to other histone deacetylases, displays selectivity for a single histone mark, H3K18Ac, directly linked to control of gene expression. H3K18Ac is mainly present around the transcription start site of genes and has been linked to activation of nuclear hormone receptors. SIRT7 thereby acts as a transcription repressor. Moreover, H3K18 hypoacetylation has been reported as a marker of malignancy in various cancers and seems to maintain the transformed phenotype of cancer cells. These data suggest that SIRT7 may play a key role in oncogenic transformation by suppresses expression of tumor suppressor genes by locus-specific deacetylation of H3K18Ac at promoter regions. Also required to restore the transcription of ribosomal RNA (rRNA) at the exit from mitosis: promotes the association of RNA polymerase I with the rDNA promoter region and coding region. Stimulates transcription activity of the RNA polymerase I complex. May also deacetylate p53/TP53 and promotes cell survival, however such data need additional confirmation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5973R-A750

Anti-SIRT7 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-5973R-A750)
Supplier: Bioss
Description: NAD-dependent protein deacetylase that specifically mediates deacetylation of histone H3 at 'Lys-18' (H3K18Ac). In contrast to other histone deacetylases, displays selectivity for a single histone mark, H3K18Ac, directly linked to control of gene expression. H3K18Ac is mainly present around the transcription start site of genes and has been linked to activation of nuclear hormone receptors. SIRT7 thereby acts as a transcription repressor. Moreover, H3K18 hypoacetylation has been reported as a marker of malignancy in various cancers and seems to maintain the transformed phenotype of cancer cells. These data suggest that SIRT7 may play a key role in oncogenic transformation by suppresses expression of tumor suppressor genes by locus-specific deacetylation of H3K18Ac at promoter regions. Also required to restore the transcription of ribosomal RNA (rRNA) at the exit from mitosis: promotes the association of RNA polymerase I with the rDNA promoter region and coding region. Stimulates transcription activity of the RNA polymerase I complex. May also deacetylate p53/TP53 and promotes cell survival, however such data need additional confirmation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5973R-A555

Anti-SIRT7 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-5973R-A555)
Supplier: Bioss
Description: NAD-dependent protein deacetylase that specifically mediates deacetylation of histone H3 at 'Lys-18' (H3K18Ac). In contrast to other histone deacetylases, displays selectivity for a single histone mark, H3K18Ac, directly linked to control of gene expression. H3K18Ac is mainly present around the transcription start site of genes and has been linked to activation of nuclear hormone receptors. SIRT7 thereby acts as a transcription repressor. Moreover, H3K18 hypoacetylation has been reported as a marker of malignancy in various cancers and seems to maintain the transformed phenotype of cancer cells. These data suggest that SIRT7 may play a key role in oncogenic transformation by suppresses expression of tumor suppressor genes by locus-specific deacetylation of H3K18Ac at promoter regions. Also required to restore the transcription of ribosomal RNA (rRNA) at the exit from mitosis: promotes the association of RNA polymerase I with the rDNA promoter region and coding region. Stimulates transcription activity of the RNA polymerase I complex. May also deacetylate p53/TP53 and promotes cell survival, however such data need additional confirmation.
UOM: 1 * 100 µl
Product Image-BELL55-93

Accessories for CBM910 impact printers B+S

Supplier: BELLINGHAM STANLEY
Description: Paper rolls for CBM910, For: CBM910 printer

Image Unavailable-BOSSBS-2646R-FITC

Anti-LAG3 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-2646R-FITC)
Supplier: Bioss
Description: Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.
UOM: 1 * 100 µl
Image Unavailable-WAKF294-36231

Toximaster® QC8 software

Supplier: FUJIFILM WAKO CHEMICALS
Description: The Toximaster® QC8 software supports data processing based on the protocols complying with three types of pharmacopeia (USP, EP, JP) for bacterial endotoxin testing. This software is compliant with FDA 21 CFR Part 11 ERES (electronic records/electronic signature), which requires the proper information from all parties involved in the testing of the sample.

Product Image-99509.180

VWR®, Medical Grade viscosity standards

Supplier: VWR Chemicals
Description: Medical Grade viscosity standards provide certified dynamic viscosity data at 25 and 37 °C, are dual-certified to ISO 17025 and ISO 17034 under UKAS and are ideal for the calibration and verification of viscosity measuring equipment.

MSDS

Image Unavailable-BOSSBS-2646R-CY7

Anti-LAG3 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-2646R-CY7)
Supplier: Bioss
Description: Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2646R-CY3

Anti-LAG3 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-2646R-CY3)
Supplier: Bioss
Description: Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.
UOM: 1 * 100 µl
Product Image-85621.680

VWR®, Powder packs for determination of phosphate, reagents for photometers

Supplier: VWR Chemicals
Description: VWR® powder pack reagents are designed to be used on laboratory and portable photometers with 16 mm cell capability. No calibration data is necessary. The pillows, individually sealed in aluminium foil packs, are unaffected by ambient conditions and contain pre-measured powder reagents for accuracy, convenience and great solubility.

MSDS

Image Unavailable-BOSSBS-3594R

Anti-GRIM19 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-3594R)
Supplier: Bioss
Description: A novel gene, Genes associated with Retinoid IFN induced Mortality (GRIM) GRIM19 gene was identified. Antisense expression of GRIM19 confers a strong resistance against IFN/RA induced death by reducing the intracellular levels of GRIM19 protein. Overexpression of GRIM19 enhances cell death in response to IFN/RA. GRIM19 is primarily a nuclear protein whose expression is induced by the IFN/RA combination. These data indicate that GRIM19 is a novel cell death regulatory molecule.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3594R-CY5

Anti-NDUFA13 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-3594R-CY5)
Supplier: Bioss
Description: A novel gene, Genes associated with Retinoid IFN induced Mortality (GRIM) GRIM19 gene was identified. Antisense expression of GRIM19 confers a strong resistance against IFN/RA induced death by reducing the intracellular levels of GRIM19 protein. Overexpression of GRIM19 enhances cell death in response to IFN/RA. GRIM19 is primarily a nuclear protein whose expression is induced by the IFN/RA combination. These data indicate that GRIM19 is a novel cell death regulatory molecule.
UOM: 1 * 100 µl
Product Image-BRDY321957

Magicard™ Prima 8 Uno Laminator

Catalog Number: (BRDY321957)
Supplier: Brady
Description: The Magicard Prima 8 printer provides a compact, reliable and robust solution for instant issuance and lamination.
UOM: 1 * 1 items

New Product


Image Unavailable-713-3007

Accessories for printer WTW meters

Supplier: WTW
Description: Printer connection cable, AK CR/P, for CR 3200 and CR 4200 thermoreactors

Product Image-634-1244

UV/VIS Spectrophotometers

Supplier: VWR Collection
Description: <p>The UH5200 features a 10,4” backlit colour LCD display with 800×600-pixel resolution to allow detailed visualisation of calibration curves and measured spectra. The UH5200 is a standalone instrument that may also be controlled from a PC by installing the optional UV Solutions Plus software package. Measured data may be stored in the instrument´s on-board memory or on USB drives.</p>

New Product

Image Unavailable-BOSSBS-2646R-CY5.5

Anti-LAG3 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-2646R-CY5.5)
Supplier: Bioss
Description: Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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