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Catalog Number: (BOSSBS-13248R-A680)
Supplier: Bioss
Description: Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e., adenylyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of G alpha subunits have been identified; these include Gs, Gi, Gq and Ga 12/13 (3,4). The Gi class comprises all the known a subunits that are susceptible to pertussis toxin modifications, including Ga i-1, Ga i-2, Ga i-3, Ga o, Ga t1, Ga t2, Ga z and Ga gust (4). Of these, the three Ga i subtypes function to open atrial potassium channels (6). Ga 16 is a member of the Gq subfamily and is expressed specifically in hematopoietic cells (7).
UOM: 1 * 100 µl


Catalog Number: (564-0298)
Supplier: PEAK SCIENTIFIC
Description: The Precision Nitrogen Headspace 250 has been conceived and custom-engineered to meet the gas requirements for headspace sampler instruments requiring higher gas pressure.
UOM: 1 * 1 items


Catalog Number: (564-0284)
Supplier: PEAK SCIENTIFIC
Description: Designed as a dedicated solution for MP-AES instruments supplying high purity nitrogen for plasma support gas or monochromator purge and dry air supply for POP gas and monochromator air purge, Halo produces 25 L/min of 99,5% or 10 L/min of 99,95% pure nitrogen with a supporting dry air supply of up to 36,5 L/min. Fitted with an oxygen analyser, Halo will alert when operating purity has been reached through a purity status indicating LED light.
UOM: 1 * 1 items


Supplier: VWR Collection
Description: These ready to use thermometers, with probe, are designed for temperature measurements which require high accuracy. They can be used for general purpose applications in air, gas, liquid and solids measurements, depending on the probe type. They are suitable for use in pharmaceutical and biotechnology companies (production and laboratories in the food industry), dairy products, fish, meat, healthcare, blood, government institutes and the environment.

Catalog Number: (PEAK3301768)
Supplier: PEAK SCIENTIFIC
Description: The Precision Hydrogen Trace 1200 generator is designed primarily for GC carrier gas use, and can also be used for detectors requiring hydrogen fuel gas such as FID and FPD. One generator is capable of supplying multiple GC instruments.
UOM: 1 * 1 items


Catalog Number: (BOSSBS-12003R)
Supplier: Bioss
Description: Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (e.g., adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, beta and gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their alpha subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. More recent evidence, however, has established an important regulatory role for the beta gamma subunits (6-8). The Gs subfamily of G alpha subunits includes two closely related proteins, Ga s and Ga olf, which respectively stimulate adenylate cyclase and mediate response to olfactory stimuli (9).
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-9599R-A350)
Supplier: Bioss
Description: The sense of taste provides animals with valuable information about the quality and nutritional value of food. There are four widely accepted categories of taste perception, sweet, bitter, salty, and sour. A controversial fifth taste, known as umami or monosodium glutamate (MSG), has also been described. A family of G protein coupled receptors are involved in taste perception, and includes T1R, which is involved in sweet and umami taste perception, and T2R, which is involved in bitter taste perception. The T1R family consists of three members, T1R1, T1R2, and T1R3 (1-4). These proteins form heterodimers, which alters the selectivity of the subunits (1-4). The T1R2 and T1R3 heterodimer functions as a receptor for sweet taste, and recognizes several sweet-tasting molecules, such as sucrose, saccharin, dulcin, and acesulfame-K (1–4). The T1R1 and T1R3 heterodimer recognizes L-amino-acids to perceive umami taste. Sweet taste transduction is carried out by two pathways (2). First, sucrose and other sugars activate Gas via the T1Rs, which activates adenylyl cyclase to generate cAMP. Artificial sweeteners bind to either Gbg or Gaq coupled T1Rs to activate PLCb2 and generate IP3 and DAG. Both pathways ultimately lead to neurotransmitter release. The mouse T1R3 gene maps to chromosome 4 near the Sac locus, a primary determinant of sweet preference in mice, and it is expressed in a subset of taste cells in circumvallate, foliate, and fungiform taste papillae.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-9599R-A488)
Supplier: Bioss
Description: The sense of taste provides animals with valuable information about the quality and nutritional value of food. There are four widely accepted categories of taste perception, sweet, bitter, salty, and sour. A controversial fifth taste, known as umami or monosodium glutamate (MSG), has also been described. A family of G protein coupled receptors are involved in taste perception, and includes T1R, which is involved in sweet and umami taste perception, and T2R, which is involved in bitter taste perception. The T1R family consists of three members, T1R1, T1R2, and T1R3 (1-4). These proteins form heterodimers, which alters the selectivity of the subunits (1-4). The T1R2 and T1R3 heterodimer functions as a receptor for sweet taste, and recognizes several sweet-tasting molecules, such as sucrose, saccharin, dulcin, and acesulfame-K (1–4). The T1R1 and T1R3 heterodimer recognizes L-amino-acids to perceive umami taste. Sweet taste transduction is carried out by two pathways (2). First, sucrose and other sugars activate Gas via the T1Rs, which activates adenylyl cyclase to generate cAMP. Artificial sweeteners bind to either Gbg or Gaq coupled T1Rs to activate PLCb2 and generate IP3 and DAG. Both pathways ultimately lead to neurotransmitter release. The mouse T1R3 gene maps to chromosome 4 near the Sac locus, a primary determinant of sweet preference in mice, and it is expressed in a subset of taste cells in circumvallate, foliate, and fungiform taste papillae.
UOM: 1 * 100 µl


Catalog Number: (564-0285)
Supplier: PEAK SCIENTIFIC
Description: For laboratories using any single quad LC-MS systems, the Genius SQ 24 nitrogen gas generator delivers analytical grade nitrogen supply dedicated for this instrument. With a compact size to fit under most laboratory benches and flow rates of up to 24 L/min, meeting and exceeding the maximum flow rate required by any Single Quad LC-MS on the market today, your laboratory can enjoy hassle free nitrogen gas which helps deliver the best analytical results.
UOM: 1 * 1 items


Supplier: DWK Life Sciences
Description: Bottles, pressure plus+, DURAN® borosilicate glass 3.3, clear. Safe working under pressure or vacuum, sampling under pressure, storage of gas generating media. With easy to read scale and large labelling field for easy marking, in fired-on, highly durable white ceramic.

Catalog Number: (PEAK3303147)
Supplier: PEAK SCIENTIFIC
Description: Producing between 10 and 520 L/min of high purity nitrogen gas, the Infinity XE 60 series nitrogen membrane gas generators can comfortably supply multiple laboratory instruments with instrument grade nitrogen.
UOM: 1 * 1 items


Catalog Number: (564-0280)
Supplier: PEAK SCIENTIFIC
Description: Designed to the specifications of the Bruker EVOQ triple Quadrupole's gas requirements delivering dry air at up to 50 L/min and nitrogen at up to 32 L/min.
UOM: 1 * 1 items


Catalog Number: (PEAK3304532)
Supplier: PEAK SCIENTIFIC
Description: Bringing Single Quad LC-MS users the very latest in nitrogen gas generator technology, Horizen 24 is the culmination of over 25 years at the forefront of nitrogen gas generation for the laboratory.
UOM:

New Product


Catalog Number: (PEAK3304886)
Supplier: PEAK SCIENTIFIC
Description: The Collision Gas Add-On has been designed to serve a number of generators, and supplies ultra high purity nitrogen to the collision cell at a flow of up to 200 cc/min.
UOM: 1 * 1 items

New Product


Catalog Number: (PEAK3300671)
Supplier: PEAK SCIENTIFIC
Description: Solaris XE 35 generator has been engineered using membrane technology to meet the gas delivery requirements for labs using LC-MS or multiple lower flow nitrogen instruments such as ELSDs or Compact Mass Spectrometers.
UOM: 1 * 1 items


Catalog Number: (WITG2.989.500)
Supplier: witeg Labortechnik
Description: Gas generators according to Kipp, Duran.
UOM: 1 * 1 items


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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