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Catalog Number: (BOSSBS-11595R-CY3)
Supplier: Bioss
Description: Three highly similar proteins termed NOMO1, NOMO2 and NOMO3, are encoded by a gene mapping to a region of duplication on the p arm of human chromosome 16. All three NOMO proteins share similar functions and have been difficult to characterize individually. NOMO1 (Nodal modulator 1), also known as PM5, is a 1,222 amino acid highly conserved single-pass type I membrane protein expressed in colon tumor tissue and normal colonic mucosa. NOMO proteins are novel antagonists of Nodal signaling which interact with Nicalin to form a Nicalin-NOMO complex, and are rapidly degraded or stabilized by Nicalin. NOMO proteins were once considered candidates for the development of pseudoxanthoma elasticum (PXE), a heritable disorder of connective tissue, as the NOMO genes are located in close proximity to the gene responsible for PXE development (MRP6).
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-11595R-A750)
Supplier: Bioss
Description: Three highly similar proteins termed NOMO1, NOMO2 and NOMO3, are encoded by a gene mapping to a region of duplication on the p arm of human chromosome 16. All three NOMO proteins share similar functions and have been difficult to characterize individually. NOMO1 (Nodal modulator 1), also known as PM5, is a 1222 amino acid highly conserved single-pass type I membrane protein expressed in colon tumour tissue and normal colonic mucosa. NOMO proteins are novel antagonists of Nodal Signalling which interact with Nicalin to form a Nicalin-NOMO complex, and are rapidly degraded or stabilized by Nicalin. NOMO proteins were once considered candidates for the development of pseudoxanthoma elasticum (PXE), a heritable disorder of connective tissue, as the NOMO genes are located in close proximity to the gene responsible for PXE development (MRP6).
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-11595R-HRP)
Supplier: Bioss
Description: Three highly similar proteins termed NOMO1, NOMO2 and NOMO3, are encoded by a gene mapping to a region of duplication on the p arm of human chromosome 16. All three NOMO proteins share similar functions and have been difficult to characterize individually. NOMO1 (Nodal modulator 1), also known as PM5, is a 1,222 amino acid highly conserved single-pass type I membrane protein expressed in colon tumor tissue and normal colonic mucosa. NOMO proteins are novel antagonists of Nodal signaling which interact with Nicalin to form a Nicalin-NOMO complex, and are rapidly degraded or stabilized by Nicalin. NOMO proteins were once considered candidates for the development of pseudoxanthoma elasticum (PXE), a heritable disorder of connective tissue, as the NOMO genes are located in close proximity to the gene responsible for PXE development (MRP6).
UOM: 1 * 100 µl


Catalog Number: (PEAK10-2320)
Supplier: PEAK SCIENTIFIC
Description: The NG5000 delivers ultra high purity nitrogen at trace detection limits through Pressure Swing Adsorption technology at flows of up to 5 L/min for GC, DSC and DMA applications as well as other laboratory. This generator requires a high quality source of in-house air to supply the unit.
UOM: 1 * 1 items


Catalog Number: (BOSSBS-11595R-FITC)
Supplier: Bioss
Description: Three highly similar proteins termed NOMO1, NOMO2 and NOMO3, are encoded by a gene mapping to a region of duplication on the p arm of human chromosome 16. All three NOMO proteins share similar functions and have been difficult to characterize individually. NOMO1 (Nodal modulator 1), also known as PM5, is a 1,222 amino acid highly conserved single-pass type I membrane protein expressed in colon tumor tissue and normal colonic mucosa. NOMO proteins are novel antagonists of Nodal signaling which interact with Nicalin to form a Nicalin-NOMO complex, and are rapidly degraded or stabilized by Nicalin. NOMO proteins were once considered candidates for the development of pseudoxanthoma elasticum (PXE), a heritable disorder of connective tissue, as the NOMO genes are located in close proximity to the gene responsible for PXE development (MRP6).
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-11595R-A647)
Supplier: Bioss
Description: Three highly similar proteins termed NOMO1, NOMO2 and NOMO3, are encoded by a gene mapping to a region of duplication on the p arm of human chromosome 16. All three NOMO proteins share similar functions and have been difficult to characterize individually. NOMO1 (Nodal modulator 1), also known as PM5, is a 1,222 amino acid highly conserved single-pass type I membrane protein expressed in colon tumor tissue and normal colonic mucosa. NOMO proteins are novel antagonists of Nodal signaling which interact with Nicalin to form a Nicalin-NOMO complex, and are rapidly degraded or stabilized by Nicalin. NOMO proteins were once considered candidates for the development of pseudoxanthoma elasticum (PXE), a heritable disorder of connective tissue, as the NOMO genes are located in close proximity to the gene responsible for PXE development (MRP6).
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-11595R-A350)
Supplier: Bioss
Description: Three highly similar proteins termed NOMO1, NOMO2 and NOMO3, are encoded by a gene mapping to a region of duplication on the p arm of human chromosome 16. All three NOMO proteins share similar functions and have been difficult to characterize individually. NOMO1 (Nodal modulator 1), also known as PM5, is a 1,222 amino acid highly conserved single-pass type I membrane protein expressed in colon tumor tissue and normal colonic mucosa. NOMO proteins are novel antagonists of Nodal signaling which interact with Nicalin to form a Nicalin-NOMO complex, and are rapidly degraded or stabilized by Nicalin. NOMO proteins were once considered candidates for the development of pseudoxanthoma elasticum (PXE), a heritable disorder of connective tissue, as the NOMO genes are located in close proximity to the gene responsible for PXE development (MRP6).
UOM: 1 * 100 µl


Catalog Number: (PEAK10-1295)
Supplier: PEAK SCIENTIFIC
Description: The NG5000(A) delivers ultra high purity nitrogen at trace detection limits through Pressure Swing Adsorption technology at flows of up to 5 L/min for GC, DSC, DMA and other applications. The NG5000(A) comes with an internal compressor for laboratories without an external source of gas.
UOM: 1 * 1 items


Catalog Number: (PRSI33-175)
Supplier: ProSci Inc.
Description: CD46 acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. It may be involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46 acts as a co-stimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.
UOM: 1 * 100 µG

New Product


Catalog Number: (PRSI33-456)
Supplier: ProSci Inc.
Description: UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
UOM: 1 * 100 µG

New Product


Catalog Number: (APOSPC4513-1G)
Supplier: Apollo Scientific
Description: Heptafluoropropyl 1,2,2,2-tetrafluoroethyl ether 1g pack 1 * 1 g
UOM: 1 * 1 g

New Product


Supplier: VWR Chemicals
Description: Diethyl ether stabilised Ph. Eur.
Catalog Number: (23806.328)
Supplier: VWR Chemicals
Description: Diethyl ether ≥99% stabilised, GPR RECTAPUR® peroxide-free
UOM: 1 * 2,5 L

Supplier: Avantor
Description: Diethyl ether stabilised, BAKER ANALYZED®, Laboratory Reagent, J.T.Baker®
Catalog Number: (6783-25)
Supplier: MACRON AVANTOR BRAND
Description: Diethyl ether ≥99.5%, AR®, Macron Fine Chemicals™
UOM: 1 * 2,5 L

Catalog Number: (6727-25)
Supplier: MACRON AVANTOR BRAND
Description: Diethyl ether, ChromAR® for HPLC, Macron Fine Chemicals™
UOM: 1 * 2,5 L

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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