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Catalog Number: (BOSSBS-13018R-A750)
Supplier: Bioss
Description: DNA polymerase activity is essential for replication, repair, recombination and mutagenesis. DNA polymerases can often bypass DNA lesions that block DNA replication, thereby allowing the replication of damaged DNA. One such DNA polymerase is the distributive enzyme DNA Pol i, which is encoded by the POLI gene. POLI is located on human chromosome 18q21.2, a region often implicated in the etiology of many human cancers. At thymine templates, DNA Pol i is highly error-prone when replicating undamaged DNA in that it favors the misincorporation of guanine over the correct nucleotide, adenosine. DNA Pol i also promotes the replication of damaged DNA by misincorporating deoxynucleotides opposite DNA lesions. DNA Pol i acts sequentially with DNA Pol , which is essential for damage-induced mutagenesis, to complete the DNA lesion bypass. Therefore, replication involving DNA Pol i is likely to be highly mutagenic.
UOM: 1 * 100 µl


Supplier: VISION ENGINEERING
Description: Accessory for microscopes, Protection caps for 4× IOTA objectives

Catalog Number: (BOSSBS-13018R-A680)
Supplier: Bioss
Description: DNA polymerase activity is essential for replication, repair, recombination and mutagenesis. DNA polymerases can often bypass DNA lesions that block DNA replication, thereby allowing the replication of damaged DNA. One such DNA polymerase is the distributive enzyme DNA Pol i, which is encoded by the POLI gene. POLI is located on human chromosome 18q21.2, a region often implicated in the etiology of many human cancers. At thymine templates, DNA Pol i is highly error-prone when replicating undamaged DNA in that it favors the misincorporation of guanine over the correct nucleotide, adenosine. DNA Pol i also promotes the replication of damaged DNA by misincorporating deoxynucleotides opposite DNA lesions. DNA Pol i acts sequentially with DNA Pol , which is essential for damage-induced mutagenesis, to complete the DNA lesion bypass. Therefore, replication involving DNA Pol i is likely to be highly mutagenic.
UOM: 1 * 100 µl


Catalog Number: (BSBTA01376-1)
Supplier: Boster Bio
Description: Rabbit IgG polyclonal antibody for DNA Polymerase iota detection. Tested with WB in Human;Mouse;Rat.
UOM: 1 * 100 µG


Catalog Number: (VISIMTA411)
Supplier: VISION ENGINEERING
Description: Accessory for microscopes, Set for white LED modules for IOTA
UOM: 1 * 1 items


Catalog Number: (VISISMI212)
Supplier: VISION ENGINEERING
Description: Mantis Iota compact ergonomic stereo microscope. Easy to use with interchangeable lenses. Bench stand with integrated substage illumination. Magnification from 3 to 8× (objectives to be added).
UOM:

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Supplier: VISION ENGINEERING
Description: IOTA is a compact eyepiece-less optical stereo microscope with dynamic perspective optics.

Catalog Number: (BOSSBS-12326R)
Supplier: Bioss
Description: VpreB is expressed in pre-B lymphocytes, but not in mature B cells or in other blood cell lineages. The gene which encodes VpreB maps to human chromosome 22q11.2. The VpreB and Lambda 5 genes encode the Iota and Omega polypeptide chains, respectively, which associate with the Ig-Mu chain to form a molecular complex that is expressed on the surface of pre-B cells. This complex presumably regulates Ig gene rearrangements in the early steps of B cell differentiation. In the mouse the two genes are simultaneously expressed in pre-B cells and belong to the same transcription unit. A primary transcript is synthesized from which the pre-B and Lambda 5 mRNAs are derived by alternative splicing. In the human, however, the two genes are separate and do not belong to the same transcription unit.
UOM: 1 * 100 µl


Catalog Number: (ANTIA277763-100)
Supplier: ANTIBODIES.COM
Description: Mouse monoclonal [PRKCI/4911] antibody to PKC iota for IHC-P with samples derived from human, feline and canine.
UOM: 1 * 100 µG

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Catalog Number: (ANTIA307646-100)
Supplier: ANTIBODIES.COM
Description: Rabbit polyclonal antibody to PKC iota for WB with samples derived from Human, Mouse and Rat.
UOM: 1 * 100 µl

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Catalog Number: (ANTIA13760-100)
Supplier: ANTIBODIES.COM
Description: Anti-DNA Polymerase iota Rabbit Polyclonal Antibody
UOM: 1 * 100 µl

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Catalog Number: (ANTIA277764-100)
Supplier: ANTIBODIES.COM
Description: Mouse monoclonal [PRKCI/4912] antibody to PKC iota for IHC-P with samples derived from human.
UOM: 1 * 100 µG

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Catalog Number: (ANTIA278352-100)
Supplier: ANTIBODIES.COM
Description: Mouse monoclonal [PRKCI/4912] antibody to PKC iota for IHC-P with samples derived from human.
UOM: 1 * 100 µG

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Catalog Number: (BSBTPB9321)
Supplier: Boster Bio
Description: Polyclonal antibody for PKC IOTA/PRKCI detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. PKC IOTA/PRKCI information: Molecular Weight: 68262 MW; Subcellular Localization: Cytoplasm. Membrane. Endosome. Nucleus. Transported into the endosome through interaction with SQSTM1/p62. After phosphorylation by SRC, transported into the nucleus through interaction with KPNB1. Colocalizes with CDK7 in the cytoplasm and nucleus. Transported to vesicular tubular clusters (VTCs) through interaction with RAB2A; Tissue Specificity: Predominantly expressed in lung and brain, but also expressed at lower levels in many tissues including pancreatic islets. Highly expressed in non-small cell lung cancers.
UOM: 1 * 100 µG


Catalog Number: (VISISMI201)
Supplier: VISION ENGINEERING
Description: Mantis Iota compact ergonomic stereo microscope. Easy to use with interchangeable lenses. Flexible articulated arm. Magnification from 3 to 8× (objectives to be added).
UOM: 1 * 1 items

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Catalog Number: (ANTIA321856-100)
Supplier: ANTIBODIES.COM
Description: Anti-DNA Polymerase iota Mouse Monoclonal Antibody [clone: OTI1H9]
UOM: 1 * 100 µG

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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