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Image Unavailable-BOSSBS-5038R-HRP

Anti-APOE Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-5038R-HRP)
Supplier: Bioss
Description: Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
UOM: 1 * 100 µl
Product Image-479-2288

Cryobank vials and Bank-It™ tube system, Nunc™

Clearance
Supplier: Thermo Fisher Scientific
Description: These cryogenic vials have the same features as the standard cryotubes. They are designed for long term low temperature storage. Some vials have laser etched unique 2D barcodes that allow for tracking of the samples. The codes are permanently attached so they do not separate from the vials. Barcoded vials feature standard microplate format racks.

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Image Unavailable-44651.AE

ICP-MS internal standard solution, Specpure®

Catalog Number: (44651.AE)
Supplier: Thermo Fisher Scientific
Description: Multi-Element Standard, 8 component standard, 100 µg/ml , Specpure®, Matrix: 5% HNO₃, Application: ICP-MS standards
UOM: 1 * 100 mL

MSDS Certificates


Product Image-479-2493

Nunc™ Universal Latch Racks for 48 Storage Tubes

Supplier: Thermo Fisher Scientific
Description: Use versatile Thermo Scientific™ Nunc™ 1,8 ml Externally-threaded universal tubes inside a large storage system, or in smaller scale when used for traditional cryostorage in dewars. Available racked or in bulk, with 2D barcodes or non-coded.

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Image Unavailable-BOSSBS-6501R-CY7

Anti-RAB25 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-6501R-CY7)
Supplier: Bioss
Description: RAB proteins, such as RAB25, are members of the RASsuperfamily of small GTPases that are involved in membranetrafficking. Members of the RAB11 subfamily, including RAB25,control the return of internalized membrane-associated moieties tothe cell surface
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7877R-CY5

Anti-NEDD4 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-7877R-CY5)
Supplier: Bioss
Description: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity. Monoubiquitinates IGF1R at multiple sites, thus leading to receptor internalization and degradation in lysosomes. Ubiquitinates FGFR1, leading to receptor internalization and degradation in lysosomes. Promotes ubiquitination of RAPGEF2. According to PubMed:18562292 the direct link between NEDD4 and PTEN regulation through polyubiquitination described in PubMed:17218260 is questionable. Involved in ubiquitination of ERBB4 intracellular domain E4ICD. Involved in the budding of many viruses. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. Ubiquitinates TNK2 and regulates EGF-induced degradation of EGFR and TNF2. Involved in the ubiquitination of ebola virus VP40 protein and this ubiquitination plays a role in facilitating viral budding.
UOM: 1 * 100 µl
Product Image-620-3306

Air/infrared surface thermometer, testo 810

Catalog Number: (620-3306)
Supplier: Testo
Description: The testo 810 allows the measurement of air temperature and simultaneous non contact surface temperature measurement in one instrument. Come complete with illuminated display.
UOM: 1 * 1 items
Image Unavailable-BOSSBS-5690R-CY3

Anti-RAB24 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-5690R-CY3)
Supplier: Bioss
Description: A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. The GTPase Rab24 is thought to be involved in the regulation of vesicular transport associated with autophagy.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6501R-HRP

Anti-RAB25 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-6501R-HRP)
Supplier: Bioss
Description: RAB proteins, such as RAB25, are members of the RASsuperfamily of small GTPases that are involved in membranetrafficking. Members of the RAB11 subfamily, including RAB25,control the return of internalized membrane-associated moieties tothe cell surface
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5691R-A488

Anti-RAB24 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-5691R-A488)
Supplier: Bioss
Description: A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. The GTPase Rab24 is thought to be involved in the regulation of vesicular transport associated with autophagy.
UOM: 1 * 100 µl
Product Image-BOSSBS-7898R

Anti-PICK1 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-7898R)
Supplier: Bioss
Description: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
UOM: 1 * 100 µl
Image Unavailable-TUTTTEDGE11230PED

Autoclaves, T-Edge

Supplier: TUTTNAUER
Description: The T-Edge 10 and T-Edge 11 are space-saving tabletop autoclaves that give you high speed Class B performance saving you time so you can assist your patients, while meeting current international standards and regulatory requirements to protect your staff and patients.

Image Unavailable-BOSSBS-7877R-HRP

Anti-NEDD4 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-7877R-HRP)
Supplier: Bioss
Description: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity. Monoubiquitinates IGF1R at multiple sites, thus leading to receptor internalization and degradation in lysosomes. Ubiquitinates FGFR1, leading to receptor internalization and degradation in lysosomes. Promotes ubiquitination of RAPGEF2. According to PubMed:18562292 the direct link between NEDD4 and PTEN regulation through polyubiquitination described in PubMed:17218260 is questionable. Involved in ubiquitination of ERBB4 intracellular domain E4ICD. Involved in the budding of many viruses. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. Ubiquitinates TNK2 and regulates EGF-induced degradation of EGFR and TNF2. Involved in the ubiquitination of ebola virus VP40 protein and this ubiquitination plays a role in facilitating viral budding.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6239R

Anti-SH3KBP1 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-6239R)
Supplier: Bioss
Description: SH3KBP1 belongs to the CIN85/CMS family of adaptor molecules, characterized by containing three N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The different members of the family orchestrate a network involved in dowregulation and degradation of recpetor tyrosine kinases. SH3KBP1 is involved in regulating diverse signal transduction pathways. Involved in the regulation of endocytosis and lysosomal degradation of ligand-induced receptor tyrosine kinases, including EGFR and MET/hepatocyte growth factor receptor, through a association with CBL and endophilins. In the case of EGF receptor turnover, its activation involves recruitment of SH3KBP1- endophilin complexes to mediate internalization. Once internalized, RTKs are delivered into the endosomal compartment where receptors get sorted for either recycling back to the cell surface or are targeted to lysosomes for degradation. Alternate splicing results in multiple transcript variants.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4228R-CY5.5

Anti-VLDLR Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-4228R-CY5.5)
Supplier: Bioss
Description: Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7898R-HRP

Anti-PICK1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-7898R-HRP)
Supplier: Bioss
Description: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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