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Image Unavailable-BOSSBS-6697R-CY7

Anti-DICER1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-6697R-CY7)
Supplier: Bioss
Description: Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6895R-A555

Anti-FGG Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-6895R-A555)
Supplier: Bioss
Description: Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
UOM: 1 * 100 µl
Image Unavailable-ERGODSVSTEPGK

Floor signs, DuraStripe ®, Supreme V, steps

Supplier: ERGOMAT
Description: DuraStripe®, Supreme V foot prints are perfect for guiding traffic flow and ideal for high-impact traffic areas.

Image Unavailable-BOSSBS-7548R-CY5.5

Anti-FGA Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-7548R-CY5.5)
Supplier: Bioss
Description: Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.
UOM: 1 * 100 µl
Product Image-BOHLC430-28

Special stirrer bearings, BOLA

Supplier: Bohlender
Description: Stirrer bearings made of PTFE, provides a safe seat in the reactor lid. The stirrer shaft is held by an invisible shaft guide made of borosilicate glass which has an adjustable vacuum sealing.

Image Unavailable-DYNCKITMUTMO2001

Lower guide rail M2 right (42) Muthylen

Catalog Number: (DYNCKITMUTMO2001)
Supplier: DYNACO EUROPE
Description: N/A
UOM: 1 * 1 items
Product Image-MEMMB32549I1060EPL

Accessories for IPPeco cooled incubators

Supplier: MEMMERT
Description: Reinforced stainless steel shelf, max. loading 60 kg; with guide bars and fixing screws (only in connection with option K1). Please consider max. loading of chamber, For: IPP1060eco

Image Unavailable-ERGODSVXR6WK

Floor signs, DuraStripe ®, Supreme V, X-shapes

Supplier: ERGOMAT
Description: DuraStripe®, Supreme V X shapes are perfect for guiding traffic flow and ideal for high-impact traffic areas. It also has the added benefit of having tapered edges to eliminate most of the potential tripping and impact hazards.

Product Image-549-0508

Consumables for PerkinElmer autosamplers

Supplier: Trajan Scientific and Medical
Description: Autosampler syringes for PerkinElmer AutoSystem.

Image Unavailable-BOSSBS-2743R-CY7

Anti-SLIT2 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-2743R-CY7)
Supplier: Bioss
Description: Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. In vitro, silences the attractive effect of NTN1 but not its growth-stimulatory effect and silencing requires the formation of a ROBO1-DCC complex. May be implicated in spinal chord midline post-crossing axon repulsion. In vitro, only commissural axons that crossed the midline responded to SLIT2. In the developing visual system appears to function as repellent for retinal ganglion axons by providing a repulsion that directs these axons along their appropriate paths prior to, and after passage through, the optic chiasm. In vitro, collapses and repels retinal ganglion cell growth cones. Seems to play a role in branching and arborization of CNS sensory axons, and in neuronal cell migration. In vitro, Slit homolog 2 protein N-product, but not Slit homolog 2 protein C-product, repels olfactory bulb (OB) but not dorsal root ganglia (DRG) axons, induces OB growth cones collapse and induces branching of DRG axons. Seems to be involved in regulating leukocyte migration.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2743R-A350

Anti-SLIT2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-2743R-A350)
Supplier: Bioss
Description: Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. In vitro, silences the attractive effect of NTN1 but not its growth-stimulatory effect and silencing requires the formation of a ROBO1-DCC complex. May be implicated in spinal chord midline post-crossing axon repulsion. In vitro, only commissural axons that crossed the midline responded to SLIT2. In the developing visual system appears to function as repellent for retinal ganglion axons by providing a repulsion that directs these axons along their appropriate paths prior to, and after passage through, the optic chiasm. In vitro, collapses and repels retinal ganglion cell growth cones. Seems to play a role in branching and arborization of CNS sensory axons, and in neuronal cell migration. In vitro, Slit homolog 2 protein N-product, but not Slit homolog 2 protein C-product, repels olfactory bulb (OB) but not dorsal root ganglia (DRG) axons, induces OB growth cones collapse and induces branching of DRG axons. Seems to be involved in regulating leukocyte migration.
UOM: 1 * 100 µl
Product Image-BOHLC425-12

Stirrer Bearings, glass

Supplier: Bohlender
Description: Combination of borosilicate glass piece with ground joint, an interior PTFE shaft guide with integrated special gasket and a GL screw cap made
of polyphenylene sulphide.

Product Image-631-1753

VWR®, Ring Lights for VisiLight® LED

Catalog Number: (631-1753)
Supplier: VWR Collection
Description: Ring light, VWR®, For: VisiLight® LED, Fibre optic ring light (inner Ø = 66 mm / L = 750 mm)
UOM: 1 * 1 items
Image Unavailable-SARS85.1638.200

Blood collection needles

Catalog Number: (SARS85.1638.200)
Supplier: SARSTEDT
Description: The needle protection on the safety-needles and Safety-Multifly® needles enables the safe termination of blood collection by locking the needle in the needle protector.
UOM: 1 * 480 items
Product Image-BOCH1132

Forceps with guide pin, straight

Supplier: BOCHEM
Description: Stainless steel.

Product Image-631-0545

Fully automated rotary microtome, CUT 6062

Catalog Number: (631-0545)
Supplier: Slee
Description: The CUT 6062 is a fully automated rotary microtome equipped with maintenance-free caged roller bearing guide ways and micrometre feed mechanism to provide the highest stability and precision.
UOM: 1 * 1 items
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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