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Catalog Number: (BOSSBS-6659R-A488)
Supplier: Bioss
Description: Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. When associated with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarized intestinal cells, by generating and delivering intracellular signals. When associated with SLC7A5, plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-6659R-CY5.5)
Supplier: Bioss
Description: Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. When associated with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarized intestinal cells, by generating and delivering intracellular signals. When associated with SLC7A5, plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-6659R-A680)
Supplier: Bioss
Description: Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. When associated with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarised intestinal cells, by generating and delivering intracellular signals. When associated with SLC7A5, plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier.
UOM: 1 * 100 µl


Catalog Number: (PRSI96-663)
Supplier: ProSci Inc.
Description: S100 calcium-binding protein A10 (S100A10), a member of the S100 family of proteins containing two EF-hand calcium-binding motifs, is also known as protein S100-A10, calpactin I light chain, cellular ligand of annexin II, p10 protein and p11, which can be found as a free monomer, a homodimer, or a heterotetramer composed of a p11 dimer complex with two molecules of annexin II. S100A10 is an integral part of cellular structural scaffolding that interacts with plasma membrane proteins through its association with annexin II. S100A10 also works together with cytosolic and peripheral membrane-associated proteins such as AHNAK in the development of the intracellular membrane. Furthermore,S100A10 has been implicated in the transportation of proteins involved in mood regulation, nociception, and cell polarization. Complexed with the annexin II, S100A10 binds receptor and channel proteins and guides them to the cell surface, resulting in increased membrane localization and consequent magnified functional expression of these proteins.
UOM: 1 * 100 µG


Catalog Number: (PRSI96-138)
Supplier: ProSci Inc.
Description: CD antigen CD98 is also known as 4F2 cell-surface antigen heavy chain (4F2hc), 4F2 heavy chain antigen, Solute carrier family 3 member 2 (SLC3A2), Lymphocyte activation antigen 4F2 large subunit, is a single-pass type I I membrane protein which belongs to the SLC3A transporter family.. SLC3A2 / CD98 is expressed ubiquitously in all tissues tested with highest levels detected in kidney, placenta and testis and weakest level in thymus. SLC3A2 / CD98 is required for the function of light chain amino-acid transporters and also involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. CD98 involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A5 or SLC7A8, CD98 involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarized intestinal cells, by generating and delivering intracellular signals.
UOM: 1 * 100 µG


Supplier: WAKU GERATE
Description: Light, aluminium safety steps. Strong double rails with robust, tension and pressure resistant bracings for increased stability. Platform height corresponds to height of top step.

Catalog Number: (HAVE205323669)
Supplier: VWR Collection
Description: Guide rod classic/TwinNut 1000 mm (1 piece), VWR®, For: EML 450 digital plus
UOM: 1 * 1 items


Catalog Number: (HITA810-1008)
Supplier: VWR Collection
Description: These spare parts are suitable for certain HPLC pumps.
UOM: 1 * 1 items


Supplier: COWIE
Description: High Performance (HP) shaft guides provide an effective guide for use with glass and metal shaft stirrers over a wide range of temperatures without shedding particles from a specially formulated PTFE-PEEK seal whilst maintaining vacuum. The moulded-in PTFE-PEEK guide ring located at the end of the taper provides a guide to assist alignment of the shaft.

Catalog Number: (MILFXX6504713)
Supplier: Merck
Description: Test kit, Naval fluid colour guide
UOM: 1 * 1 items


Catalog Number: (548-2515A)
Supplier: VWR Collection
Description: Almost all septa have one laminated side with PTFE (high chemical resistance) and form an inert barrier between carrier material and sample.
UOM: 1 * 50 items


Supplier: BOCHEM
Description: Castors for transport container, made of 18/10 stainless steel, with 4 rubber guided rolls, 1 lockable.

Supplier: LEICA MICROSYSTEMS
Description: Reliable, reproducible, advanced cell checks. Make your cell culture experiments more reliable and consistent with AI-powered algorithms and analysis.

New Product

Supplier: Trajan Scientific and Medical
Description: * Gas-tight.

Supplier: Trajan Scientific and Medical
Description: Septa, BTO premium high-temperature centre guide GC septa, Ø: 9 mm, Max. temp.: 400 °C

Catalog Number: (BOSSBS-3998R)
Supplier: Bioss
Description: Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
UOM: 1 * 100 µl


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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