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Product Image-212-0461

Test tubes, with rim, medium wall

Supplier: MURRAY S
Description: Borosilicate test tubes are suitable for all usual laboratory applications. They will withstand temperature change up to and including boiling of samples. They are also highly chemically resistant.

Product Image-STMC78059.1

Mouse Recombinant M-CSF (E.coli-expressed)

Supplier: STEMCELL Technologies
Description: Macrophage colony-stimulating factor (M-CSF) is a homodimeric glycoprotein growth factor that regulates proliferation and differentiation of myeloid hematopoietic progenitors to mononuclear phagocytic cell lineages, including monocytes, macrophages, and osteoclasts. M-CSF is a crucial factor for the development of tissue-resident macrophages in most tissues (Ginhoux andamp; Jung). It is required for the maturation and activation of monocytes and macrophages, and regulates inflammatory responses in conjunction with other stimuli such as IFN-γ, LPS, and IL-4 (Murray <i>et al.</i>). M-CSF is also required for bone resorption by osteoclasts, and is involved in the development and regulation of placenta, mammary gland, and brain. M-CSF is produced by monocytes, fibroblasts, osteoclasts, stromal cells, endothelial cells, and tumor cells (Chockalingam andamp; Ghosh). M-CSF exerts its biological effects by signaling through a receptor tyrosine kinase (CSF-1R or M-CSF-R) encoded by the c-fms proto-oncogene (Hamilton). CSF-1R shares similar structural features with other growth factor receptors, including the stem cell factor (SCF) receptor, platelet-derived growth factor receptor (PDGF-R), and Flt3/Flk-2 receptor tyrosine kinase. Stimulation of the CSF-1R upon binding to M-CSF activates MAPK, PI3K, and PLCγ signaling pathways (Chockalingam andamp; Ghosh). Human and mouse M-CSF sequences are highly conserved both at nucleotide and amino acid levels (80% homology; DeLamarter <i>et al.</i>).

Product Image-233-0010

Bone cutters

Supplier: MURRAY S
Description: Carbon steel, nickel plated. With overlapping spring or coil spring handle.

Product Image-STMC78150.1

Human Recombinant M-CSF, ACF

Supplier: STEMCELL Technologies
Description: Macrophage colony-stimulating factor (M-CSF) is a homodimeric glycoprotein growth factor that regulates proliferation and differentiation of myeloid hematopoietic progenitors to mononuclear phagocytic cell lineages, including monocytes, macrophages, and osteoclasts. M-CSF is a crucial factor for the development of tissue-resident macrophages in most tissues (Ginhoux andamp; Jung). It is required for the maturation and activation of monocytes and macrophages, and regulates inflammatory responses in conjunction with other stimuli such as IFN-γ, LPS, and IL-4 (Murray <i>et al.</i>). M-CSF is also required for bone resorption by osteoclasts, and is involved in the development and regulation of placenta, mammary gland, and brain. M-CSF is produced by monocytes, fibroblasts, osteoclasts, stromal cells, endothelial cells, and tumor cells (Chockalingam andamp; Ghosh). M-CSF exerts its biological effects by signaling through a receptor tyrosine kinase (CSF-1R or M-CSF-R) encoded by the c-fms proto-oncogene (Hamilton). CSF-1R shares similar structural features with other growth factor receptors, including the stem cell factor (SCF) receptor, platelet-derived growth factor receptor (PDGF-R), and Flt3/Flk-2 receptor tyrosine kinase. Stimulation of the CSF-1R upon binding to M-CSF activates MAPK, PI3K, and PLCγ signaling pathways (Chockalingam andamp; Ghosh). Human and mouse M-CSF sequences are highly conserved both at nucleotide and amino acid levels (80% homology; DeLamarter <i>et al.</i>). This product is animal component-free.

Product Image-MURRM618/05

Hypodermic needles

Supplier: MURRAY S
Description: Non sterile needles with sharp ends and luer lock fitting.

Product Image-STMC78057.2

Human Recombinant M-CSF (E.coli-expressed)

Supplier: STEMCELL Technologies
Description: Macrophage colony-stimulating factor (M-CSF) is a homodimeric glycoprotein growth factor that regulates proliferation and differentiation of myeloid hematopoietic progenitor cells to mononuclear phagocytic cell lineages, including monocytes, macrophages, and osteoclasts. M-CSF is a crucial factor for the development of tissue-resident macrophages in most tissues (Ginhoux and Jung). It is required for the maturation and activation of monocytes and macrophages, and regulates inflammatory responses in conjunction with other stimuli such as IFN-γ, LPS, and IL-4 (Murray <i>et al.</i>). M-CSF is also required for bone resorption by osteoclasts, and is involved in the development and regulation of the placenta, mammary gland, and brain. M-CSF is produced by monocytes, fibroblasts, osteoclasts, stromal cells, endothelial cells, and tumor cells (Chockalingam and Ghosh). M-CSF exerts its biological effects by signaling through a receptor tyrosine kinase (CSF-1R or M-CSF-R) encoded by the c-fms proto-oncogene (Hamilton). CSF-1R shares similar structural features with other growth factor receptors, including the stem cell factor (SCF) receptor, platelet-derived growth factor receptor (PDGF-R), and Flt3/Flk-2 receptor tyrosine kinase. Stimulation of the CSF-1R upon binding to M-CSF activates MAPK, PI3K, and PLCγ signaling pathways (Chockalingam and Ghosh). Human and mouse M-CSF sequences are highly conserved both at nucleotide and amino acid levels (80% homology; DeLamarter <i>et al.</i>).

Image Unavailable-MURRT103/V4

VIAL ROLLED RIM 21.25ML 1 * 162 items

Catalog Number: (MURRT103/V4)
Supplier: MURRAY S
Description: VIAL ROLLED RIM 21.25ML 1 * 162 items
UOM: 1 * 162 items
Image Unavailable-MURRM621/07

NEEDLE HYPODERMIC N-STERIL 21GAUGE 120MM 1 * 10 items

Catalog Number: (MURRM621/07)
Supplier: MURRAY S
Description: NEEDLE HYPODERMIC N-STERIL 21GAUGE 120MM 1 * 10 items
UOM: 1 * 10 items
Image Unavailable-MURRP024/05

JERRICAN PE CLEAR NARROW NECK WITH CAP 2 1 * 1 items

Catalog Number: (MURRP024/05)
Supplier: MURRAY S
Description: JERRICAN PE CLEAR NARROW NECK WITH CAP 2 1 * 1 items
UOM: 1 * 1 items
Image Unavailable-MURRG051/01

CAPS FOR 12MM GLASS SPEC/TUBE 1 * 100 items

Catalog Number: (MURRG051/01)
Supplier: MURRAY S
Description: CAPS FOR 12MM GLASS SPEC/TUBE 1 * 100 items
UOM: 1 * 100 items
Image Unavailable-MURRN518/B4

SPENCER GRIP 8 INCH 1 * 1 items

Catalog Number: (MURRN518/B4)
Supplier: MURRAY S
Description: SPENCER GRIP 8 INCH 1 * 1 items
UOM: 1 * 1 items
Image Unavailable-MURR1352/05

DISSECTING FORCEPS 290MM 1 * 1 items

Catalog Number: (MURR1352/05)
Supplier: MURRAY S
Description: DISSECTING FORCEPS 290MM 1 * 1 items
UOM: 1 * 1 items
Image Unavailable-MURRCP4UC53

BOTTLES WIDE MOUTH 100ML WITH CAP PK53 1 * 53 items

Catalog Number: (MURRCP4UC53)
Supplier: MURRAY S
Description: BOTTLES WIDE MOUTH 100ML WITH CAP PK53 1 * 53 items
UOM: 1 * 53 items
Image Unavailable-MURRCA1000TE10

BOTTLE CLEAR 1000MLT/E CAP EPE LINER 1 * 10 items

Catalog Number: (MURRCA1000TE10)
Supplier: MURRAY S
Description: BOTTLE CLEAR 1000MLT/E CAP EPE LINER 1 * 10 items
UOM: 1 * 10 items
Image Unavailable-MURRP205/15P605/10

160ml Snap secure containers with cap, tamper evident, 94mm x 54mm 1 * 220 items

Catalog Number: (MURRP205/15P605/10)
Supplier: MURRAY S
Description: 160ml Snap secure containers with cap, tamper evident, 94mm x 54mm 1 * 220 items
UOM: 1 * 220 items
Image Unavailable-MURRY263/03

DISSECTING SET FOR ZOOLOGY OXFORD 1 * 1 items

Catalog Number: (MURRY263/03)
Supplier: MURRAY S
Description: DISSECTING SET FOR ZOOLOGY OXFORD 1 * 1 items
UOM: 1 * 1 items
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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