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Image Unavailable-BOSSBS-13394R-A750

Anti-Glutaredoxin 2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.
Catalog Number: BOSSBS-13394R-A750
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-13394R-A555

Anti-GLRX2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Description: Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.
Catalog Number: BOSSBS-13394R-A555
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-0657R-A750

Anti-MRP1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyses ATP with low efficiency.
Catalog Number: BOSSBS-0657R-A750
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-0657R-CY3

Anti-ABCC1 Rabbit Polyclonal Antibody (Cy3®)

Description: Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.
Catalog Number: BOSSBS-0657R-CY3
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-0657R-A488

Anti-ABCC1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.
Catalog Number: BOSSBS-0657R-A488
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-0657R-HRP

Anti-ABCC1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.
Catalog Number: BOSSBS-0657R-HRP
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-0657R-A647

Anti-ABCC1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Description: Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.
Catalog Number: BOSSBS-0657R-A647
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-USBI127610

Anti-GSTO2 Mouse Polyclonal Antibody

Description: Anti-GSTO2 Mouse Polyclonal Antibody
Catalog Number: USBI127610
UOM: 1 * 50 µG
Supplier: US Biological
Product Image-ROCK100-101-200

Anti-GST Goat Polyclonal Antibody

Description: Primary Goat Anti-Glutathion-S-Transferase (Schistosoma japonicum) Reacts with Human
Catalog Number: ROCK100-101-200
UOM: 1 * 2 mL
Supplier: Rockland Immunochemicals
Image Unavailable-BOSSBS-9909R-A680

Anti-GGT6 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: GGT6 belongs to the gamma-glutamyltransferase family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis. GGT6 has very limited amino acid similarity to GGT1 and it's enzymatic activities are currently uncharacterised. GGT assays are of current widespread clinical use to help assess tissue damage.
Catalog Number: BOSSBS-9909R-A680
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-0657R-CY5.5

Anti-ABCC1 Rabbit Polyclonal Antibody (Cy5.5®)

Description: Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.
Catalog Number: BOSSBS-0657R-CY5.5
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-0657R-FITC

Anti-ABCC1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.
Catalog Number: BOSSBS-0657R-FITC
UOM: 1 * 100 µl
Supplier: Bioss
Product Image-PRSI38-203

Anti-SERPINI1 Rabbit Polyclonal Antibody

Description: Neuroserpin is a member of the serpin superfamily and is predominantly expressed by neurons of the developing and adult brain. This serpin is secreted from axonal growth cones of the CNS and PNS where it inhibits the enzyme tissue plasminogen activator. The expression pattern of neuroserpin and its in vivo inhibitory activity implicate this serpin in regulating axonal growth, reducing seizure activity, controlling damage in cerebral infarction and regulating emotional behaviour and memory. Four different mutations have been described in the human neuroserpin gene that promote neuroserpin abnormal polymerization, giving rise to intraneuronal inclusion bodies and a new form of dementia called Familial Encephalopathy with Neuroserpin Inclusion Bodies.
Catalog Number: PRSI38-203
UOM: 1 * 100 µG
Supplier: ProSci Inc.
Product Image-PRSI3227

Anti-ACE2 Rabbit Polyclonal Antibody

Description: ACE2 Antibody: Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor of the SARS coronavirus. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function.
Catalog Number: PRSI3227
UOM: 1 * 100 µG
Supplier: ProSci Inc.
Product Image-PRSI28-536

Anti-MCM4 Rabbit Polyclonal Antibody

Description: The protein encoded by MCM4 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. The MCM4 gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks.
Catalog Number: PRSI28-536
UOM: 1 * 100 µG
Supplier: ProSci Inc.
Image Unavailable-BOSSBS-3097R-A555

Anti-CDK9 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Description: Protein kinase involved in the regulation of transcription. Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) POLR2A, SUPT5H and RDBP. This complex is inactive when in the 7SK snRNP complex form. Phosphorylates EP300, MYOD1, RPB1/POLR2A and AR, and the negative elongation factors DSIF and NELF. Regulates cytokine inducible transcription networks by facilitating promoter recognition of target transcription factors (e.g. TNF-inducible RELA/p65 activation and IL-6-inducible STAT3 signaling). Promotes RNA synthesis in genetic programs for cell growth, differentiation and viral pathogenesis. P-TEFb is also involved in cotranscriptional histone modification, mRNA processing and mRNA export. Modulates a complex network of chromatin modifications including histone H2B monoubiquitination (H2Bub1), H3 lysine 4 trimethylation (H3K4me3) and H3K36me3; integrates phosphorylation during transcription with chromatin modifications to control co-transcriptional histone mRNA processing. The CDK9/cyclin-K complex has also a kinase activity towards CTD of RNAP II and can substitute for CDK9/cyclin-T P-TEFb in vitro. Replication stress response protein; the CDK9/cyclin-K complex is required for genome integrity maintenance, by promoting cell cycle recovery from replication arrest and limiting single-stranded DNA amount in response to replication stress, thus reducing the breakdown of stalled replication forks and avoiding DNA damage. In addition, probable function in DNA repair of isoform 2 via interaction with KU70/XRCC6. Promotes cardiac myocyte enlargement.
Catalog Number: BOSSBS-3097R-A555
UOM: 1 * 100 µl
Supplier: Bioss
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