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Product Image-DIDAPOD013132

Diode laser, green, Class II and IIIa

Description: Extremely luminous beam, ideal for classroom experiments. Class IIIa (5 mW Power)
Catalog Number: DIDAPOD013132
UOM: 1 * 1 items
Supplier: DIDALAB
Image Unavailable-NEUB0500-10-33

Electrolysis apparatus according to Hoffmann

Description: Electrolysis apparatus according to Hoffmann, made of borosilicate glass 3.3.
Catalog Number: NEUB0500-10-33
UOM: 1 * 1 items
Supplier: NEUBERT VOLUME GLASSWAERE
Product Image-552-0282

TLC education material kit, micro-set M

Description: Materials kit for scientific education.
Catalog Number: 552-0282
UOM: 1 * 1 items
Supplier: MACHEREY-NAGEL
Image Unavailable-BOSSBS-0175R-A750

Anti-TrkB Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4. Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2. Upon ligand-binding, undergoes homodimerisation, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades. Through SHC1, FRS2, SH2B1, SH2B2 activates the GRB2-Ras-MAPK cascade that regulates for instance neuronal differentiation including neurite outgrowth. Through the same effectors controls the Ras-PI3 kinase-AKT1 signaling cascade that mainly regulates growth and survival. Through PLCG1 and the downstream protein kinase C-regulated pathways controls synaptic plasticity. Thereby, plays a role in learning and memory by regulating both short term synaptic function and long-term potentiation. PLCG1 also leads to NF-Kappa-B activation and the transcription of genes involved in cell survival. Hence, it is able to suppress anoikis, the apoptosis resulting from loss of cell-matrix interactions. May also play a role in neutrophin-dependent calcium signaling in glial cells and mediate communication between neurons and glia.
Catalog Number: BOSSBS-0175R-A750
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-LIOF10522

TBX agar

Description: X-glucuronide, contained in the TBX agar formulation, is the chromogenic agent that allows the determination of the β-Dglucuronidase activity, which is a highly specific enzyme for <i>E. coli.</i> Gram-positive bacteria are inhibited by bile salts.
Catalog Number: LIOF10522
UOM: 1 * 20 items
Supplier: LIOFILCHEM

New Product


Image Unavailable-BOSSBS-11528R-CY3

Anti-GALR3 Rabbit Polyclonal Antibody (Cy3®)

Description: GALR3 a 368 and 370 amino acid protein in human and rat, respectively, belongs to a family of G protein-coupled receptors that bind the neuropeptide galanin, which is distributed throughout the central and peripheral nervous system, the pituitary gland, the gastrointestinal tract and in the endocrine and exocrine pancreas. GALR3 mRNA is widely distributed, but expressed at low abundance. In human, GALR3 mRNA is highly expressed in the hypothalamus, pituitary and testis, and is expressed to a lesser extent in adrenal gland and pancreas. Rat and human GALR3 co-express with potassium channel subunits GIRK1 and GIRK4. Like GALR1, GALR3 signaling pathways lead to the inhibition of adenylate cyclase and to the activation of potassium channels, which are linked to the regulation of neurotransmitter release. Binding of galanin to galanin receptors results in increased feeding, impaired learning, enhanced opiate analgesia and decreased opiate place preference.
Catalog Number: BOSSBS-11528R-CY3
UOM: 1 * 100 µl
Supplier: Bioss
Product Image-EDVO141

Experimentation kits, blood-based cancer diagnostics

Description: Cancer cells differ from normal cells by the combinations of proteins that are present on their surfaces. Antibodies against these proteins will specifically bind to cancer cells and not to normal cells. This allows early detection of cancer and potentially a way of delivering cancer therapies. In this simulation experiment the reaction of cancer cell markers and their corresponding antigens are demonstrated.
Catalog Number: EDVO141
UOM: 1 * 1 items
Supplier: EDVOTEK

MSDS


Product Image-DIDAPOD010240

Optical plate

Description: Optical glass components are manufactured with high accuracy polishing and flatness tolerance.
Catalog Number: DIDAPOD010240
UOM: 1 * 1 items
Supplier: DIDALAB
Product Image-EDVO118-C

Kits: cholesterol diagnostics, Ready-to-Load™

Description: Genetic testing can be used to identify people with a genetic condition which caused them to have an elevated level of cholesterol and which can be fatal. Students can see how genetic testing is carried out and learn about DNA electrophoresis.
Catalog Number: EDVO118-C
UOM: 1 * 1 items
Supplier: EDVOTEK
Product Image-DIDAPOD060930

Optical equipment to demonstrate the law of polarisation

Description: This comprehensive optical pack allows you to implement and study the basic principles of polarisation of light.
Catalog Number: DIDAPOD060930
UOM: 1 * 1 items
Supplier: DIDALAB
Product Image-MANA814400

TLC education advanced kit, micro-set F3

Description: Advanced kit for science education.
Catalog Number: MANA814400
UOM: 1 * 1 items
Supplier: MACHEREY-NAGEL
Image Unavailable-BOSSBS-13390R-FITC

Anti-GLUD2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: GLUD2 is both mitochondrial matrix enzymes belonging to the Glu/Leu/Phe/Val dehydrogenases family. Exisiting as homohexamers, GLUD1 catalyzes the oxidative deamination of glutamate to ?ketoglutarate and ammonia while GLUD2 is involved in the recycling of glutamate during neurotransmission. GLUD1 is critical for regulating amino acid induced insulin secretion and is allosterically activated by ADP and inhibited by GTP and ATP. Mutations in the gene encoding GLUD1 causes hyperinsulinism-hyperammonemia syndrome (HHS), which is an inherited condition characterized by high insulin and ammonia levels in the blood. GLUD1 may also be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. GLUD2 is expressed in testis and retina, with lower levels found in brain.
Catalog Number: BOSSBS-13390R-FITC
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-13390R-A488

Anti-GLUD2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: GLUD2 is both mitochondrial matrix enzymes belonging to the Glu/Leu/Phe/Val dehydrogenases family. Exisiting as homohexamers, GLUD1 catalyzes the oxidative deamination of glutamate to ?ketoglutarate and ammonia while GLUD2 is involved in the recycling of glutamate during neurotransmission. GLUD1 is critical for regulating amino acid induced insulin secretion and is allosterically activated by ADP and inhibited by GTP and ATP. Mutations in the gene encoding GLUD1 causes hyperinsulinism-hyperammonemia syndrome (HHS), which is an inherited condition characterized by high insulin and ammonia levels in the blood. GLUD1 may also be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. GLUD2 is expressed in testis and retina, with lower levels found in brain.
Catalog Number: BOSSBS-13390R-A488
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-13390R-A350

Anti-GLUD2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Description: GLUD2 is both mitochondrial matrix enzymes belonging to the Glu/Leu/Phe/Val dehydrogenases family. Exisiting as homohexamers, GLUD1 catalyzes the oxidative deamination of glutamate to ?ketoglutarate and ammonia while GLUD2 is involved in the recycling of glutamate during neurotransmission. GLUD1 is critical for regulating amino acid induced insulin secretion and is allosterically activated by ADP and inhibited by GTP and ATP. Mutations in the gene encoding GLUD1 causes hyperinsulinism-hyperammonemia syndrome (HHS), which is an inherited condition characterized by high insulin and ammonia levels in the blood. GLUD1 may also be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. GLUD2 is expressed in testis and retina, with lower levels found in brain.
Catalog Number: BOSSBS-13390R-A350
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-13390R-A750

Anti-GLUD2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: GLUD2 is both mitochondrial matrix enzymes belonging to the Glu/Leu/Phe/Val dehydrogenases family. Exisiting as homohexamers, GLUD1 catalyzes the oxidative deamination of glutamate to ?ketoglutarate and ammonia while GLUD2 is involved in the recycling of glutamate during neurotransmission. GLUD1 is critical for regulating amino acid induced insulin secretion and is allosterically activated by ADP and inhibited by GTP and ATP. Mutations in the gene encoding GLUD1 causes hyperinsulinism-hyperammonemia syndrome (HHS), which is an inherited condition characterized by high insulin and ammonia levels in the blood. GLUD1 may also be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. GLUD2 is expressed in testis and retina, with lower levels found in brain.
Catalog Number: BOSSBS-13390R-A750
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-13390R-HRP

Anti-GLUD2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: GLUD2 is both mitochondrial matrix enzymes belonging to the Glu/Leu/Phe/Val dehydrogenases family. Exisiting as homohexamers, GLUD1 catalyzes the oxidative deamination of glutamate to ?ketoglutarate and ammonia while GLUD2 is involved in the recycling of glutamate during neurotransmission. GLUD1 is critical for regulating amino acid induced insulin secretion and is allosterically activated by ADP and inhibited by GTP and ATP. Mutations in the gene encoding GLUD1 causes hyperinsulinism-hyperammonemia syndrome (HHS), which is an inherited condition characterized by high insulin and ammonia levels in the blood. GLUD1 may also be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. GLUD2 is expressed in testis and retina, with lower levels found in brain.
Catalog Number: BOSSBS-13390R-HRP
UOM: 1 * 100 µl
Supplier: Bioss
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