You Searched For: N-Boc-S-methyl-L-cysteine

Supplier: Apollo Scientific

Description: tert-Butyl-4-carbamoylpiperidine-1-carboxylate

Catalog Number: (APOSOR14684-5G)

Supplier: Apollo Scientific

Description: (S)-1-(tert-Butoxycarbonyl)piperidine-2-carboxylic acid

UOM: 1 * 5 g

Sale

Supplier: Thermo Fisher Scientific

Description: Appearance: Off-white to beige Low melting solid

MSDS

Supplier: Apollo Scientific

Description: tert-Butyl-4-methylenepiperidine-1-carboxylate

Catalog Number: (APOSOR313035-5G)

Supplier: Apollo Scientific

Description: tert-Butyl-3-formylpyrrolidine-1-carboxylate 98%

UOM: 1 * 5 g

Sale

Catalog Number: (PRSI26-882)

Supplier: ProSci Inc.

Description: Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A. NARF binds to the prenylated prelamin A carboxyl-terminal tail domain. It may be a component of a prelamin A endoprotease complex. NARF is located in the nucleus, where it partially colocalizes with the nuclear lamina. It shares limited sequence similarity with iron-only bacterial hydrogenases.Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A. The protein encoded by this gene binds to the prenylated prelamin A carboxyl-terminal tail domain. It may be a component of a prelamin A endoprotease complex. The encoded protein is located in the nucleus, where it partially colocalizes with the nuclear lamina. It shares limited sequence similarity with iron-only bacterial hydrogenases. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene, including one with a novel exon that is generated by RNA editing.

UOM: 1 * 50 µG

Sale

Supplier: Thermo Fisher Scientific

Description: tert-Butyl-2-(hydroxymethyl)pyrrolidine-1-carboxylate 98%

MSDS Certificates

Supplier: Apollo Scientific

Description: tert-Butyl-2,5-dihydro-1H-pyrrole-1-carboxylate

Supplier: Thermo Fisher Scientific

Description: Appearance: White Powder

MSDS

Supplier: Thermo Fisher Scientific

Description: ethyl-2-((tert-butoxycarbonyl)amino)acetate 95%

Certificates

Supplier: Thermo Fisher Scientific

Description: tert-Butyl (piperidin-4-ylmethyl)carbamate 97%

MSDS

Catalog Number: (APOSOR52690-1G)

Supplier: Apollo Scientific

Description: (1R,3S)-3-(tert-Butoxycarbonylamino)cyclohexanecarboxylic acid 97+%

UOM: 1 * 1 g

Sale

Catalog Number: (APOSOR4610-10G)

Supplier: Apollo Scientific

Description: (S)-tert-Butyl-2-cyanopyrrolidine-1-carboxylate 97%

UOM: 1 * 10 g

Sale

Catalog Number: (PRSI29-200)

Supplier: ProSci Inc.

Description: MBD1 belongs to a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MBD1 can also repress transcription from methylated gene promoters. Five transcript variants of the MBD1 are generated by alternative splicing resulting in protein isoforms that contain one MBD domain, two to three cysteine-rich (CXXC) domains, and some differences in the COOH terminus. All five transcript variants repress transcription from methylated promoters; in addition, variants with three CXXC domains also repress unmethylated promoter activity. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. Five transcript variants of the MBD1 are generated by alternative splicing resulting in protein isoforms that contain one MBD domain, two to three cysteine-rich (CXXC) domains, and some differences in the COOH terminus. All five transcript variants repress transcription from methylated promoters; in addition, variants with three CXXC domains also repress unmethylated promoter activity. MBD1 and MBD2 map very close to each other on chromosome 18q21.

UOM: 1 * 100 µG

Sale

Catalog Number: (PRSI27-479)

Supplier: ProSci Inc.

Description: MBD1 belongs to a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MBD1 can also repress transcription from methylated gene promoters. Five transcript variants of the MBD1 are generated by alternative splicing resulting in protein isoforms that contain one MBD domain, two to three cysteine-rich (CXXC) domains, and some differences in the COOH terminus. All five transcript variants repress transcription from methylated promoters; in addition, variants with three CXXC domains also repress unmethylated promoter activity. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. Five transcript variants of the MBD1 are generated by alternative splicing resulting in protein isoforms that contain one MBD domain, two to three cysteine-rich (CXXC) domains, and some differences in the COOH terminus. All five transcript variants repress transcription from methylated promoters; in addition, variants with three CXXC domains also repress unmethylated promoter activity. MBD1 and MBD2 map very close to each other on chromosome 18q21.DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. Five transcript variants of the MBD1 are generated by alternative splicing resulting in protein isoforms that contain one MBD domain, two to three cysteine-rich (CXXC) domains, and some differences in the COOH terminus. All five transcript variants repress transcription from methylated promoters; in addition, variants with three CXXC domains also repress unmethylated promoter activity. MBD1 and MBD2 map very close to each other on chromosome 18q21.

UOM: 1 * 50 µG

Sale

Supplier: Thermo Fisher Scientific

Description: N-Boc-D-aspartic acid-1-methyl ester 97%

Certificates