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Product Image-763-0009

Kits: the case of the invisible bands, Ready-to-Load™

Catalog Number: (763-0009)
Supplier: EDVOTEK
Description: Experiment using fluorescence and electrophoresis to solve the mystery of the invisible bands.
UOM: 1 * 1 items
Product Image-DIDAPOD013210

He-Ne laser

Supplier: DIDALAB
Description: High quality professional gas laser, Class II

Product Image-DIDAPOD010022

Optical components for optical bench

Supplier: DIDALAB
Description: Educational Materials, Optics, Application: Physics, Polariser, calibrated, set in an M49 ring

Product Image-761-0139

Nicotine dependence chart

Catalog Number: (761-0139)
Supplier: 3B Scientific
Description: Over 30% of the world's population uses tobacco products, and 90% of that is from cigarettes. The physical effects of nicotine and the diseases it can cause, including cancer, are detailed on this anatomical poster. For such a wide spread practice education is important and this anatomy poster can help do that. This thickly laminated anatomical chart is printed on premium glossy (200 g) UV resistant paper and comes with two sided lamination (125 µm, 5,0 mil) and metal eyelets to make the chart easy to display.
UOM: 1 * 1 items
Product Image-DIDAPOD060110

High quality prismatic optical bench

Supplier: DIDALAB
Description: Triangular, cast aluminium optical bench

Product Image-216-0428

Pneumatic trough, pp, Nalgene®

Catalog Number: (216-0428)
Supplier: Thermo Fisher Scientific
Description: Replace metal-type troughs with the polypropylene pneumatic trough.
UOM: 1 * 1 items

Environmentally Preferable


Product Image-552-0288

TLC education advanced kit, micro-set F2

Catalog Number: (552-0288)
Supplier: MACHEREY-NAGEL
Description: Advanced kit for science education.
UOM: 1 * 1 KIT
Image Unavailable-BOSSBS-12401R-A350

Anti-NLE1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-12401R-A350)
Supplier: Bioss
Description: The Notch signaling pathway is an evolutionary conserved system that is involved in intracellular communication. Notch receptors play an important role in development and cell-fate decisions. Notchless is a loss-of-function mutant allele that encodes for protein NLE1 (notchless homolog 1). NLE1 is a 485 amino acid WD40-repeat protein that binds to the cytoplasmic domain of Notch, regulating its signaling activity in Drosophila melanogaster and in mice. Deletion of the NLE1 gene in mice during the early stages of development results in embryonic death, while gene deletion in the late stages of development leads to activation of a caspase-3-dependent apoptotic pathway. In plants, NLE1 is crucial for normal cellular growth and development. Under-expression during shoot proliferation causes pleiotropic defects such as delayed flowering and abnormal organ maturation. It may also play a role in 60S ribosomal subunit biogenesis in yeast. NLE1 contains eight WD40 domains and produces one isoform due to alternative splicing.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12401R-A488

Anti-NLE1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-12401R-A488)
Supplier: Bioss
Description: The Notch signaling pathway is an evolutionary conserved system that is involved in intracellular communication. Notch receptors play an important role in development and cell-fate decisions. Notchless is a loss-of-function mutant allele that encodes for protein NLE1 (notchless homolog 1). NLE1 is a 485 amino acid WD40-repeat protein that binds to the cytoplasmic domain of Notch, regulating its signaling activity in Drosophila melanogaster and in mice. Deletion of the NLE1 gene in mice during the early stages of development results in embryonic death, while gene deletion in the late stages of development leads to activation of a caspase-3-dependent apoptotic pathway. In plants, NLE1 is crucial for normal cellular growth and development. Under-expression during shoot proliferation causes pleiotropic defects such as delayed flowering and abnormal organ maturation. It may also play a role in 60S ribosomal subunit biogenesis in yeast. NLE1 contains eight WD40 domains and produces one isoform due to alternative splicing.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12401R-HRP

Anti-NLE1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-12401R-HRP)
Supplier: Bioss
Description: The Notch signaling pathway is an evolutionary conserved system that is involved in intracellular communication. Notch receptors play an important role in development and cell-fate decisions. Notchless is a loss-of-function mutant allele that encodes for protein NLE1 (notchless homolog 1). NLE1 is a 485 amino acid WD40-repeat protein that binds to the cytoplasmic domain of Notch, regulating its signaling activity in Drosophila melanogaster and in mice. Deletion of the NLE1 gene in mice during the early stages of development results in embryonic death, while gene deletion in the late stages of development leads to activation of a caspase-3-dependent apoptotic pathway. In plants, NLE1 is crucial for normal cellular growth and development. Under-expression during shoot proliferation causes pleiotropic defects such as delayed flowering and abnormal organ maturation. It may also play a role in 60S ribosomal subunit biogenesis in yeast. NLE1 contains eight WD40 domains and produces one isoform due to alternative splicing.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13390R-CY7

Anti-GLUD2 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-13390R-CY7)
Supplier: Bioss
Description: GLUD2 is both mitochondrial matrix enzymes belonging to the Glu/Leu/Phe/Val dehydrogenases family. Exisiting as homohexamers, GLUD1 catalyzes the oxidative deamination of glutamate to ?ketoglutarate and ammonia while GLUD2 is involved in the recycling of glutamate during neurotransmission. GLUD1 is critical for regulating amino acid induced insulin secretion and is allosterically activated by ADP and inhibited by GTP and ATP. Mutations in the gene encoding GLUD1 causes hyperinsulinism-hyperammonemia syndrome (HHS), which is an inherited condition characterized by high insulin and ammonia levels in the blood. GLUD1 may also be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. GLUD2 is expressed in testis and retina, with lower levels found in brain.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12401R-CY7

Anti-NLE1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-12401R-CY7)
Supplier: Bioss
Description: The Notch signaling pathway is an evolutionary conserved system that is involved in intracellular communication. Notch receptors play an important role in development and cell-fate decisions. Notchless is a loss-of-function mutant allele that encodes for protein NLE1 (notchless homolog 1). NLE1 is a 485 amino acid WD40-repeat protein that binds to the cytoplasmic domain of Notch, regulating its signaling activity in Drosophila melanogaster and in mice. Deletion of the NLE1 gene in mice during the early stages of development results in embryonic death, while gene deletion in the late stages of development leads to activation of a caspase-3-dependent apoptotic pathway. In plants, NLE1 is crucial for normal cellular growth and development. Under-expression during shoot proliferation causes pleiotropic defects such as delayed flowering and abnormal organ maturation. It may also play a role in 60S ribosomal subunit biogenesis in yeast. NLE1 contains eight WD40 domains and produces one isoform due to alternative splicing.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12401R-FITC

Anti-NLE1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-12401R-FITC)
Supplier: Bioss
Description: The Notch signaling pathway is an evolutionary conserved system that is involved in intracellular communication. Notch receptors play an important role in development and cell-fate decisions. Notchless is a loss-of-function mutant allele that encodes for protein NLE1 (notchless homolog 1). NLE1 is a 485 amino acid WD40-repeat protein that binds to the cytoplasmic domain of Notch, regulating its signaling activity in Drosophila melanogaster and in mice. Deletion of the NLE1 gene in mice during the early stages of development results in embryonic death, while gene deletion in the late stages of development leads to activation of a caspase-3-dependent apoptotic pathway. In plants, NLE1 is crucial for normal cellular growth and development. Under-expression during shoot proliferation causes pleiotropic defects such as delayed flowering and abnormal organ maturation. It may also play a role in 60S ribosomal subunit biogenesis in yeast. NLE1 contains eight WD40 domains and produces one isoform due to alternative splicing.
UOM: 1 * 100 µl
Product Image-EDVO986

Experimentation kits, analysis and comparision of mammalian cell types

Catalog Number: (EDVO986)
Supplier: EDVOTEK
Description: Observe the differences between mammalian cell types and how these cells funciton. Cells are fixed on microscope slides and students stain the cells on the slide to view morphological characteristics of the cell types. These cells are very safe for classroom use.
UOM: 1 * 1 items
Image Unavailable-BOSSBS-13390R-A647

Anti-GLUD2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-13390R-A647)
Supplier: Bioss
Description: GLUD2 is both mitochondrial matrix enzymes belonging to the Glu/Leu/Phe/Val dehydrogenases family. Exisiting as homohexamers, GLUD1 catalyzes the oxidative deamination of glutamate to ?ketoglutarate and ammonia while GLUD2 is involved in the recycling of glutamate during neurotransmission. GLUD1 is critical for regulating amino acid induced insulin secretion and is allosterically activated by ADP and inhibited by GTP and ATP. Mutations in the gene encoding GLUD1 causes hyperinsulinism-hyperammonemia syndrome (HHS), which is an inherited condition characterized by high insulin and ammonia levels in the blood. GLUD1 may also be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. GLUD2 is expressed in testis and retina, with lower levels found in brain.
UOM: 1 * 100 µl
Product Image-EDVO271

Experimentation kits, simulation of HIV detection by ELISA

Catalog Number: (EDVO271)
Supplier: EDVOTEK
Description: An HIV test detects HIV infection indirectly using an ELISA test against HIV antibodies in the blood. The test works by taking antibodies from the patient's blood and adding them to a microtitre plate coated with HIV antigen. If HIV antibodies are present, they will bind to the antigens on the plate. In this experiment, students perform an ELISA text by coating microtitre plate wells with simulated HIV antigen and then test simulated donor serum for anti-HIV antibodies.
UOM: 1 * 1 items
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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