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Image Unavailable-BOSSBS-12177R-CY7

Anti-KCNT2 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-12177R-CY7)
Supplier: Bioss
Description: Voltage-gated K+ channels in the plasma membrane are important regulators of electrical signaling, controlling the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. KCNT2 is a 1,135 amino acid multi-pass transmembrane protein belonging to the potassium channel family (calcium-activated subfamily) of proteins. KCNT2 produces rapidly activating outward rectifier potassium currents in reponse to high intracellular sodium and chloride levels. Its channel activity is inhibited by ATP, inhalation anesthetics, such as isoflourane, and upon stimulation of G-protein coupled receptors, such as mAChR M1 and GluR-1. There are four isoforms of KCNT2 that are produced as a result of alternative splicing events.
UOM: 1 * 100 µl
Product Image-HACH2349832

Accessories for test kits, general boiler water, drop count titration

Supplier: Hach
Description: Accessory for test kit, Chloride titrant for low range testing, includes silver nitrate, 100 ml marked dropping bottle, Range: 5 - 100 mg/l

Image Unavailable-733-1633

Sodium chloride 5 mol/l (5 N) in aqueous solution, AccuGENE®

Catalog Number: (733-1633)
Supplier: LONZA
Description: Sodium chloride 5 mol/l (5 N) in aqueous solution, AccuGENE®
UOM: 1 * 1 L

Certificates


Product Image-302636.1000

Silver nitrate 0.04 mol/l (0.04 N) in aqueous solution

Catalog Number: (302636.1000)
Supplier: VWR Chemicals
Description: Silver nitrate 0.04 mol/l (0.04 N) in aqueous solution
UOM: 1 * 1 L

MSDS


Image Unavailable-BOSSBS-12177R-A488

Anti-KCNT2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-12177R-A488)
Supplier: Bioss
Description: Voltage-gated K+ channels in the plasma membrane are important regulators of electrical signaling, controlling the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. KCNT2 is a 1,135 amino acid multi-pass transmembrane protein belonging to the potassium channel family (calcium-activated subfamily) of proteins. KCNT2 produces rapidly activating outward rectifier potassium currents in reponse to high intracellular sodium and chloride levels. Its channel activity is inhibited by ATP, inhalation anesthetics, such as isoflourane, and upon stimulation of G-protein coupled receptors, such as mAChR M1 and GluR-1. There are four isoforms of KCNT2 that are produced as a result of alternative splicing events.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11661R-A750

Anti-KCNE3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-11661R-A750)
Supplier: Bioss
Description: Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 (PubMed:12954870). Associated with KCNC4/Kv3.4 is proposed to form the subthreshold voltage-gated potassium channel in skeletal muscle and to establish the resting membrane potential (RMP) in muscle cells. Associated with KCNQ1/KCLQT1 may form the intestinal cAMP-stimulated potassium channel involved in chloride secretion that produces a current with nearly instantaneous activation with a linear current-voltage relationship.
UOM: 1 * 100 µl
Image Unavailable-J60434.AK

Sodium chloride 5 M in aqueous solution RNase-free

Catalog Number: (J60434.AK)
Supplier: Thermo Fisher Scientific
Description: Sodium chloride 5 M in aqueous solution RNase-free
UOM: 1 * 250 mL

MSDS Certificates


Image Unavailable-BOSSBS-1945R-A680

Anti-WNK3 Protein Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-1945R-A680)
Supplier: Bioss
Description: Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Phosphorylates WNK4. Regulates the phosphorylation of SLC12A1 and SLC12A2. Increases Ca(2+) influx mediated by TRPV5 and TRPV6 by enhancing their membrane expression level via a kinase-dependent pathway. Inhibits the activity of KCNJ1 by decreasing its expression at the cell membrane in a non-catalytic manner. Isoform 1, isoform 2, isoform 3 and isoform 4 stimulate the activity of SLC12A1, SLC12A2 and SLC12A3 and inhibit the activity of SLC12A4, SLC12A5, SLC12A6 and SLC12A7. According to PubMed:19470686, isoform 1 inhibits the activity of SLC12A3.
UOM: 1 * 100 µl
Image Unavailable-SIAL39059-100ML-F

Zinc chloride 0.1 mol/l in aqueous solution, Sigma-Aldrich®

Supplier: Merck
Description: Zinc chloride 0.1 mol/l in aqueous solution, Sigma-Aldrich®

Image Unavailable-BOSSBS-1945R-FITC

Anti-WNK3 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-1945R-FITC)
Supplier: Bioss
Description: Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Phosphorylates WNK4. Regulates the phosphorylation of SLC12A1 and SLC12A2. Increases Ca(2+) influx mediated by TRPV5 and TRPV6 by enhancing their membrane expression level via a kinase-dependent pathway. Inhibits the activity of KCNJ1 by decreasing its expression at the cell membrane in a non-catalytic manner. Isoform 1, isoform 2, isoform 3 and isoform 4 stimulate the activity of SLC12A1, SLC12A2 and SLC12A3 and inhibit the activity of SLC12A4, SLC12A5, SLC12A6 and SLC12A7. According to PubMed:19470686, isoform 1 inhibits the activity of SLC12A3.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1945R-A647

Anti-WNK3 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-1945R-A647)
Supplier: Bioss
Description: Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Phosphorylates WNK4. Regulates the phosphorylation of SLC12A1 and SLC12A2. Increases Ca(2+) influx mediated by TRPV5 and TRPV6 by enhancing their membrane expression level via a kinase-dependent pathway. Inhibits the activity of KCNJ1 by decreasing its expression at the cell membrane in a non-catalytic manner. Isoform 1, isoform 2, isoform 3 and isoform 4 stimulate the activity of SLC12A1, SLC12A2 and SLC12A3 and inhibit the activity of SLC12A4, SLC12A5, SLC12A6 and SLC12A7. According to PubMed:19470686, isoform 1 inhibits the activity of SLC12A3.
UOM: 1 * 100 µl
Image Unavailable-SIAL404861-100ML

Tetrakis(hydroxymethyl)phosphonium chloride ≥80% in aqueous solution, Sigma-Aldrich®

Supplier: Merck
Description: Tetrakis(hydroxymethyl)phosphonium chloride 80% ≥80% in aqueous solution, Sigma-Aldrich®

Image Unavailable-APPC191494.0416

Potassium chloride 99.0-100.5% (by argentometric analysis, on dry substance) USP, BP, Ph. Eur., pharma grade

Supplier: PanReac AppliChem
Description: Potassium chloride 99.0-100.5% (by argentometric analysis, on dry substance) USP, BP, Ph. Eur., pharma grade

Product Image-191265J

Silver nitrate 0.02 mol/l (0.02 N) in aqueous solution, AVS TITRINORM volumetric solution

Catalog Number: (191265J)
Supplier: VWR Chemicals
Description: Silver nitrate 0.02 mol/l (0.02 N) in aqueous solution, AVS TITRINORM volumetric solution
UOM: 1 * 2,5 L

MSDS Certificates


Image Unavailable-ICNA0219142701

Potassium chloride 99.0-100.5%, crystalline powder ACS

Supplier: MP Biomedicals
Description: Soluble in water (1 g/3 ml - clear, colorless solution), boiling water (1 g/1,8 ml), glycerol (1 g/14 ml), or ethanol (1 g/250 ml); insoluble in ether or acetone; hydrochloric acid, sodium or magnesium chlorides diminish its solubility in water.

Certificates

Image Unavailable-BOSSBS-3397R-A680

Anti-SGK1 Thr256 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-3397R-A680)
Supplier: Bioss
Description: This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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