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Image Unavailable-BOSSBS-11015R-FITC

Anti-RPSA Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-11015R-FITC)
Supplier: Bioss
Description: Phakinin is a membrane-associated and cytoskeletal intermediate filament (IF) protein specific to the eye lens. IFs are cytoskeletal structures that typically contain a head, rod and tail domain. Unlike most IFs, Phakinin completely lacks the C-terminal tail domain thus contributing to the unique structure of the beaded filament that is specific to the lens. Phakinin is required for the assembly of beaded filaments and cytoskeletal networks that are important for the long-term maintenance of optical properties and transparency of the lens. Phakinin copolymerizes with Filensin, another IF protein, to form the 10-nm filamentous structures of the beaded filaments. Phakinin is also capable of self-assembling into filament-like structures that form thicker bundles. Mutations in the gene encoding Phakinin can result in lens cataract.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11015R-CY3

Anti-RPSA Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-11015R-CY3)
Supplier: Bioss
Description: Phakinin is a membrane-associated and cytoskeletal intermediate filament (IF) protein specific to the eye lens. IFs are cytoskeletal structures that typically contain a head, rod and tail domain. Unlike most IFs, Phakinin completely lacks the C-terminal tail domain thus contributing to the unique structure of the beaded filament that is specific to the lens. Phakinin is required for the assembly of beaded filaments and cytoskeletal networks that are important for the long-term maintenance of optical properties and transparency of the lens. Phakinin copolymerizes with Filensin, another IF protein, to form the 10-nm filamentous structures of the beaded filaments. Phakinin is also capable of self-assembling into filament-like structures that form thicker bundles. Mutations in the gene encoding Phakinin can result in lens cataract.
UOM: 1 * 100 µl
Product Image-786-218

Concanavalin A agarose

Supplier: G-Biosciences
Description: Concanavalin A (Con A) agarose consists of Con A coupled to 6% agarose by the cyanogen bromide method. Con A is a tetrameric metalloprotein lectin isolated from <i>Canavalia ensiformis</i> (jack bean). It is used for the purification of glycoproteins, polysaccharides and glycolipids as it binds molecules containing α-D-mannopyranosyl, α-D-glucopyranosyl and sterically related residues. It has also be used in other application areas including purification of enzyme-antibody conjugates, purification of IgM and separation of membrane vesicles. As stated above, it is a metalloprotein and to maintain its binding characteristics the presence of both Mn²⁺ and Ca²⁺ is essential. Each subunit of Con A utilises one calcium and one manganese ion and these cations can be removed under acidic conditions abolishing the carbohydrate-binding activity.

Image Unavailable-BOSSBS-11015R-A555

Anti-RPSA Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-11015R-A555)
Supplier: Bioss
Description: Phakinin is a membrane-associated and cytoskeletal intermediate filament (IF) protein specific to the eye lens. IFs are cytoskeletal structures that typically contain a head, rod and tail domain. Unlike most IFs, Phakinin completely lacks the C-terminal tail domain thus contributing to the unique structure of the beaded filament that is specific to the lens. Phakinin is required for the assembly of beaded filaments and cytoskeletal networks that are important for the long-term maintenance of optical properties and transparency of the lens. Phakinin copolymerizes with Filensin, another IF protein, to form the 10-nm filamentous structures of the beaded filaments. Phakinin is also capable of self-assembling into filament-like structures that form thicker bundles. Mutations in the gene encoding Phakinin can result in lens cataract.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11015R-A350

Anti-RPSA Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-11015R-A350)
Supplier: Bioss
Description: Phakinin is a membrane-associated and cytoskeletal intermediate filament (IF) protein specific to the eye lens. IFs are cytoskeletal structures that typically contain a head, rod and tail domain. Unlike most IFs, Phakinin completely lacks the C-terminal tail domain thus contributing to the unique structure of the beaded filament that is specific to the lens. Phakinin is required for the assembly of beaded filaments and cytoskeletal networks that are important for the long-term maintenance of optical properties and transparency of the lens. Phakinin copolymerizes with Filensin, another IF protein, to form the 10-nm filamentous structures of the beaded filaments. Phakinin is also capable of self-assembling into filament-like structures that form thicker bundles. Mutations in the gene encoding Phakinin can result in lens cataract.
UOM: 1 * 100 µl
Product Image-8183-VM

J.T.Baker®, Accessories for BAKERBOND® Protein Precipitation and Supported Liquid Extraction Plates

Supplier: Avantor
Description: Disposable reservoir tray (PVC), J.T.Baker® BAKERBOND®

Product Image-786-167

Jacalin for IgA purification

Supplier: G-Biosciences
Description: Jacalin, or <i>Artocarpus integrifolia</i> lectin, is a tetrameric two-chain lectin with a molecular weight of 66 kDa. It is a α-D-galactose binding lectin purified from jack fruit (<i>Artocarpus integrifolia</i>) seeds.

Image Unavailable-786-801

IgG purification resin, Pearl™

Supplier: G-Biosciences
Description: The Pearl™ IgG purification resin allows for the one-step purification of immunoglobulin G from serum. The resin binds the high abundant, non-IgG proteins (i.e. albumin) and allows the IgG molecules to pass through in a physiological buffer. The IgG molecules can be stored or used in downstream applications without further clean-up, such as ammonium sulphate precipitation.

Image Unavailable-ENZOBMLPW1075A0001

Proteasome Purification Kit

Catalog Number: (ENZOBMLPW1075A0001)
Supplier: ENZO LIFE SCIENCES
Description: Proteasome Purification Kit is a high integrity kit for the isolation and purification of proteasome complexes from biological samples such as cell lysates, tissue extracts, plasma, serum, confirmed by Western blot analysis.
UOM: 1 * 10 Tests
Product Image-786-266

Thiophilic adsorption kit and thiophilic resin

Supplier: G-Biosciences
Description: Thiophilic adsorption or thiophilic chromatography is a routinely used technique for the low cost, simple purification of immunoglobulins. Thiophilic adsorption was first developed by Porath et al in 1984 and is a group specific, salt-dependent purification technique that has distinct affinity towards immunoglobulins and α2- macroglobulins. The thiophilic adsorption works on the principle that some proteins in high salt are able to bind to an immobilised ligand that contains a sulfone group in proximity to a thioether group. The bound proteins are then eluted in decreasing salt concentrations. The thiophilic resin binds immunoglobulins, including IgG, IgY and IgM, from serum, ascites or tissue culture supernatants and the purified immunoglobulins are then eluted in a near neutral aqueous buffer.

Image Unavailable-786-591

Affinity purification Streptavidin Resin and buffers

Supplier: G-Biosciences
Description: Streptavidin Resin is designed for the single step small and large scale affinity purification of proteins and antibodies with a biotin tag. Biotin, a 244 Da vitamin (Vitamin H) molecule, exhibits an extraordinary binding affinity for avidin (Ka=10¹⁵ M⁻¹) and streptavidin (Ka=10¹⁵ M⁻¹). Biotin and (strept)avidin interaction is rapid and once the bond is established it can survive up to 3M guanidinehydrochloride and extremes of pH. Biotin-avidin bonds can only be reversed by denaturing the avidin protein molecule with 8M guanidine-hydrochloride at pH 1,5 or by autoclaving. The biotinylated molecules are efficiently probed with avidin or streptavidin conjugated to reporter molecules, such as peroxidases or phosphatases.

Image Unavailable-BOSSBS-13172R

Anti-BFSP1 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-13172R)
Supplier: Bioss
Description: Filensin, also referred to as CP94, CP95, or CP97, is an eye lens fiber, membrane-associated, cytoskeletal intermediate filament (IF) protein that is required for the assembly of beaded filaments, cytoskeletal networks that are necessary for the long-term maintenance of optical clarity. Phakinin copolymerizes with Filensin to make up the filamentous structures present in the beaded filaments. Filensin is also crucial for lens development since it regulates lens fiber cell shape conformation and lens transparency. Filensin contains a C-terminal non-α-helical domain that contributes in several ways to its function. The head domain of Filensin includes a di-arginine/aromatic amino acid motif that contains a potential protein kinase A phosphorylation site.
UOM: 1 * 100 µl
Image Unavailable-AGLS214303

Affinity protein expression and purification systems

Catalog Number: (AGLS214303)
Supplier: AGILENT
Description: The affinity protein expression and purification system provides a simple, gentle and effective method for high-level protein expression and purification.
UOM: 1 * 10 mL
Product Image-AGLS5185-5988

Multiple affinity removal starter reagent kits

Supplier: AGILENT
Description: Starter reagent kit for multiple affinity removal LC columns.

Product Image-30-2010

Peqlab peqGOLD TriFast™, DNA/RNA/protein purification reagent

Catalog Number: (30-2010)
Supplier: VWR Chemicals
Description: TriFast™ is a complete ready to use reagent for simultaneous isolation of RNA, DNA and proteins from liquid samples, tissue and cells.
UOM: 1 * 100 mL

MSDS Certificates


Image Unavailable-ENZOBMLSE5270010

Human recombinant DPP8

Catalog Number: (ENZOBMLSE5270010)
Supplier: ENZO LIFE SCIENCES
Description: Produced in insect cells. Active recombinant human DPP8 with an N-terminal purification tag.
UOM: 1 * 10 µG
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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