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You Searched For: Radiation+Shields


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Image Unavailable-BOSSBS-13010R-CY3

Anti-DMC1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-13010R-CY3)
Supplier: Bioss
Description: DNA repair proteins are necessary for the maintenance of chromosome integrity and are involved in the elimination of premutagenic lesions from DNA. The DNA repair proteins Rad51 and Rad52 are key components of the double-strand-break repair (DSBR) pathway. Rad51 is essential for mitotic and meiotic recombination, and its mutation in yeast and mammalian cells results in chromosome loss. Overexpression of Rad52 confers resistance to ionizing radiation and induces homologous intrachromosomal recombination. Rad52 is thought to be involved in an early stage of Rad51-mediated recombination. Additional proteins involved in the pathway include Nibrin and Dmc1. Nibrin, which complexes with Mre11 and Rad50, is absent in Nijemegen breakage syndrome (NBS) patients. Dmc1 is specifically involved in meiotic recombination. An alternative spliced form of Dmc1, designated Dmc1-D, is deleted for a region between the two motifs involved in nucleotide binding. The alternatively spliced Dmc1-D transcript is detected in both male and female germ cells, indicating that the encoded protein may have a role in mammalian genetic recombination in meiosis.
UOM: 1 * 100 µl
Image Unavailable-MMMAH617830

Speedglas™ G5-01 Heavy Duty Welding Helmets

Supplier: 3M
Description: The 3M Speedglas Heavy-Duty Welding Helmet G5-01 builds on the 9100 series. Having more adjustable features than ever - from the colour as seen through the welding filter to the direction of the airflow and the level of coverage.

Image Unavailable-BOSSBS-5164R-CY5.5

Anti-ETS1 associated Protein II Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-5164R-CY5.5)
Supplier: Bioss
Description: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12155R-CY3

Anti-CCND3 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-12155R-CY3)
Supplier: Bioss
Description: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12155R-A350

Anti-CCND3 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-12155R-A350)
Supplier: Bioss
Description: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12155R-A750

Anti-Cyclin D3 Thr283 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-12155R-A750)
Supplier: Bioss
Description: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterised by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumour suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12155R

Anti-CCND3 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-12155R)
Supplier: Bioss
Description: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].
UOM: 1 * 100 µl
Product Image-BOSSBS-8165R

Anti-RB1CC1 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-8165R)
Supplier: Bioss
Description: Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111. Involved in autophagy. Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) duting S.typhimurium infection and subsequent xenophagy. Autophagy positively regulates repair of DNA damage induced by ionizing radiation and negatively regulates apoptosis. Plays an indispensible role in fetal hematopoiesis and in the regulation of neuronal homeostasis (By similarity). Implicated in the regulation of RB1 expression. Functions as a DNA-binding transcription factor. Is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. Expression is, thus, a prerequisite for myogenic differentiation. Inhibits PTK2/FAK1 and PTK2B/PYK2 activity and activation of downstream signaling pathways.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6167R-CY3

Anti-NET1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-6167R-CY3)
Supplier: Bioss
Description: This gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6167R-A555

Anti-NET1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-6167R-A555)
Supplier: Bioss
Description: This gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
UOM: 1 * 100 µl
Product Image-MFLX32003-12

Masterflex® Direct-Read Variable-Area Flowmeters with Valve for Air, 150-mm, Avantor®

Supplier: Avantor Fluid Handling
Description: No more eye strain - front shield magnifies scale 16 percent for easier readings.

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Safety shields, Sekuroka®

Supplier: Roth Carl
Description: These safety shields are made from transparent acrylic glass of 8 mm thick.

Image Unavailable-819-0149

Anti-static clear cellulose tape with plastic core, Wescorp

Supplier: DESCO
Description: These tapes are ideal in packaging for container sealing, static shielding bag closure and holding DIP tubes.

Product Image-467-0125

Mini desiccator cabinets, SICCO, Protect

Supplier: Bohlender
Description: Orange polycarbonate panels reduce light incidence and protect samples from ultraviolet radiation. Door with snap-fit closing and integrated gasket ensure easy opening and tight closure. Suitable for use under normal pressure, temperature resistant from −35 to +70 °C.

Image Unavailable-BOSSBS-3185R-A750

Anti-Histone H2A.X Ser140 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-3185R-A750)
Supplier: Bioss
Description: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10133R-CY7

Anti-AKT1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-10133R-CY7)
Supplier: Bioss
Description: AKT1-specific substrates have been recently identified, including palladin (PALLD), which phosphorylation modulates cytoskeletal organization and cell motility; prohibitin (PHB), playing an important role in cell metabolism and proliferation; and CDKN1A, for which phosphorylation at 'Thr-145' induces its release from CDK2 and cytoplasmic relocalization. These recent findings indicate that the AKT1 isoform has a more specific role in cell motility and proliferation. Phosphorylates CLK2 thereby controlling cell survival to ionizing radiation.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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