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Image Unavailable-ENZOALX385028M010

Delphinidin chloride ≥97% (by HPLC)

Catalog Number: (ENZOALX385028M010)
Supplier: ENZO LIFE SCIENCES
Description: Anthocyanidin with antioxidant effect found in pigmented fruits and vegetables. Shown to inhibit angiogenesis and endothelial cell apoptosis by stimulating nitric oxide (NO) production. Inhibits solar radiation (UVB)-mediated oxidative stress, reducing DNA damage. Delphinidin induces necrosis in hepatocellular carcinoma cells with no caspase activation.
UOM: 1 * 10 mg
Image Unavailable-BOSSBS-12533R-CY5

Anti-DCLRE1C Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-12533R-CY5)
Supplier: Bioss
Description: Required for V(D)J recombination, the process by which exons encoding the antigen-binding domains of immunoglobulins and T-cell receptor proteins are assembled from individual V, (D), and J gene segments. V(D)J recombination is initiated by the lymphoid specific RAG endonuclease complex, which generates site specific DNA double strand breaks (DSBs). These DSBs present two types of DNA end structures: hairpin sealed coding ends and phosphorylated blunt signal ends. These ends are independently repaired by the non homologous end joining (NHEJ) pathway to form coding and signal joints respectively. This protein exhibits single-strand specific 5'-3' exonuclease activity in isolation and acquires endonucleolytic activity on 5' and 3' hairpins and overhangs when in a complex with PRKDC. The latter activity is required specifically for the resolution of closed hairpins prior to the formation of the coding joint. May also be required for the repair of complex DSBs induced by ionizing radiation, which require substantial end-processing prior to religation by NHEJ.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3542R-CY3

Anti-PNK1/PNKP Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-3542R-CY3)
Supplier: Bioss
Description: Mammalian PNK catalyzes the phosphorylation of DNA at 5'-hydroxyl termini and can dephosphorylate its 3'-phosphate termini. It plays an important function in DNA repair following ionizing radiation or oxidative damage.PNK has been reported to participate in the repair of DNA-double strand breaks via PARP-1-dependent nonhomologous end-joining.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7703R-A350

Anti-TSPYL5 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-7703R-A350)
Supplier: Bioss
Description: Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3542R-FITC

Anti-PNK1/PNKP Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-3542R-FITC)
Supplier: Bioss
Description: Mammalian PNK catalyzes the phosphorylation of DNA at 5'-hydroxyl termini and can dephosphorylate its 3'-phosphate termini. It plays an important function in DNA repair following ionizing radiation or oxidative damage.PNK has been reported to participate in the repair of DNA-double strand breaks via PARP-1-dependent nonhomologous end-joining.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8571R-A555

Anti-H2AFX Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-8571R-A555)
Supplier: Bioss
Description: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
UOM: 1 * 100 µl
Product Image-135-2340

Accessories for Heraguard™ ECO clean benches

Supplier: Thermo Scientific
Description: Retrofit kit UV-radiator for Heraguard™ ECO 0.9

Product Image-UNVT710.00.00.00

Face shield, medical, 710

Catalog Number: (UNVT710.00.00.00)
Supplier: UNIVET
Description: This face shield features an adjustable elastic band and an anallergic, interchangeable foam at the front.
UOM: 1 * 1 items
Product Image-116-0521

Standard mantory signs

Supplier: Brady
Description: Mantory signs have always a blue circular backround which contains a white pictogram.These signs display a message or action that must be carried out in a designated area.

Product Image-MMMA2805

Cover spectacles, 2800

Supplier: 3M
Description: These lightweight cover glasses (OTG) are designed to fit over most prescription spectacles with minimal interference. Available in three lens options. The green lens offers protection against infrared radiation arising from certain gas welding, gas cutting and brazing applications (IR shade 5).

Image Unavailable-BOSSBS-12155R

Anti-CCND3 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-12155R)
Supplier: Bioss
Description: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12155R-CY3

Anti-CCND3 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-12155R-CY3)
Supplier: Bioss
Description: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12155R-A350

Anti-CCND3 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-12155R-A350)
Supplier: Bioss
Description: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12155R-A750

Anti-Cyclin D3 Thr283 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-12155R-A750)
Supplier: Bioss
Description: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterised by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumour suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5164R-CY5.5

Anti-ETS1 associated Protein II Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-5164R-CY5.5)
Supplier: Bioss
Description: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0278R-CY3

Anti-RRAD Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-0278R-CY3)
Supplier: Bioss
Description: Human Rad1 is a component of a heterotrimeric PCNA like complex that also contains the Rad9 and Hus1 proteins. This complex is believed to be involved in cellular responses to DNA damage, possibly by associating with Rad17 and several components of the PCNA-loading heteropentamer, replication factor C. Human Rad1 exhibits significant homology to Rad1 from S. pombe, and its expression in yeast rad1 mutants has been shown to partially restore radiation resistance and G2 checkpoint activity. It has also been shown to possess exonuclease activity.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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