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Catalog Number: (444-2915)
Supplier: VWR Collection
Description: Digital shaker with microprocessor control which is ideal for mixing applications with heavy loads, e.g., cell cultures, solubility studies and extraction procedures. Variable speed control provides consistent, uniform shaking action. The Accu-drive shaking system delivers exceptional speed control, accuracy, safety and durability, the system continuously monitors shaking speed and will maintain set point even under changing loads.
UOM: 1 * 1 items


Supplier: VWR Collection
Description: Digital shakers with microprocessor control which are ideal for mixing applications with very heavy loads and larger vessels, e.g. cell cultures, solubility studies and extraction procedures. Variable speed control provides consistent, uniform shaking action. The Accu-drive shaking system delivers exceptional speed control, accuracy, safety and durability, the system continuously monitors shaking speed and will maintain the set point even under changing loads.

Environmentally Preferable

Supplier: VWR Collection
Description: Tube rollers are designed for the gentle, thorough mixing of a variety of containers, including Vacutainers™, bottles, test tubes, centrifuge tubes and roller bottles.

Catalog Number: (BARNSHKE416HP-1CE)
Supplier: Thermo Fisher Scientific
Description: MaxQ™ HP benchtop orbital shaker suitable for environmental rooms or on lab benches. It features balancing technology and rugged mechanism make smooth high-capacity 24/7 shaking a reality, an industry-leading platform size, wide-range speed, low heat output motor and spill-resistant design. It features set point security which restricts unauthorised or inadvertent changes to key functions. Equipped with alarm to know the shaker performance.
UOM: 1 * 1 items


Catalog Number: (BOSSBS-0800R-A488)
Supplier: Bioss
Description: Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2010].
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-6258R-FITC)
Supplier: Bioss
Description: A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-6258R-A680)
Supplier: Bioss
Description: A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.
UOM: 1 * 100 µl


Catalog Number: (SCIISI-4110)
Supplier: SCIENTIFIC INDUSTRIES ELMIS
Description: Stacking tray for MultiPlate Genie
UOM: 1 * 1 items


Supplier: ENZO LIFE SCIENCES
Description: MG-132 is a potent, cell permeable and selective proteasome inhibitor (Ki = 4 nM).1 It inhibits NF-κB activation by preventing IκB degradation (IC50 = 3 μM). The peptide blocks degradation of short-lived proteins, which in turn induces HSP and ER chaperone expression, leading to thermotolerance (1 μM MG-132, 2 h.). It also stimulates neurite outgrowth in PC12 cells (20 nM optimal). The peptide has also been reported to increase the survival rate of mesenchymal stem cells following their transplantation. IC50’s for inhibition of Suc-LLVY-AMC and Z-LLL-AMC cleaving activities of proteasome were 0,85 and 0,1 μM respectively. The ubiquitin-proteasome system (UPS) and autophagy serve as two complementary, reciprocally regulated protein degradation systems, thus blockade of UPS by MG-132 activates autophagy.

Catalog Number: (BOSSBS-11041R-FITC)
Supplier: Bioss
Description: The Bestrophins are a newly described family of anion channels unrelated in primary sequence to any previously characterized channel proteins. Bestrophins were originally defined as a family of over 20 related sequences of the C. elegans. The first mammalian Bestrophin was identified as the vitelliform macular dystrophy (VMD), 1 also known as Best disease. Three more members of the bestrophin family members were cloned and indentified recently, Bestrophin 2, 3 and 4. RT PCR analyses revealed tissue restricted expression of the three genes with both Bestrophin 1 and Bestrophin 2 are abundantly transcribed in colon. Functionally the bestrophines oligomerise to form tetramers and pentamers in order to act as calcium sensitive chloride channels. It has been shown that Bestrophin interacts with beta catalytic subunit of protein phosphatase 2A (PP2Ac). Such protein protein interaction between Bestrophin and PP2Ac and the structural subunit of PP2A, PR65, was confirmed by reciprocal immunoprecipitation. The interaction between PP2Ac and the Bestrophin takes place near the carboxy terminal end of the protein.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-11041R-A555)
Supplier: Bioss
Description: The Bestrophins are a newly described family of anion channels unrelated in primary sequence to any previously characterized channel proteins. Bestrophins were originally defined as a family of over 20 related sequences of the C. elegans. The first mammalian Bestrophin was identified as the vitelliform macular dystrophy (VMD), 1 also known as Best disease. Three more members of the bestrophin family members were cloned and indentified recently, Bestrophin 2, 3 and 4. RT PCR analyses revealed tissue restricted expression of the three genes with both Bestrophin 1 and Bestrophin 2 are abundantly transcribed in colon. Functionally the bestrophines oligomerise to form tetramers and pentamers in order to act as calcium sensitive chloride channels. It has been shown that Bestrophin interacts with beta catalytic subunit of protein phosphatase 2A (PP2Ac). Such protein protein interaction between Bestrophin and PP2Ac and the structural subunit of PP2A, PR65, was confirmed by reciprocal immunoprecipitation. The interaction between PP2Ac and the Bestrophin takes place near the carboxy terminal end of the protein.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-11041R-A488)
Supplier: Bioss
Description: The Bestrophins are a newly described family of anion channels unrelated in primary sequence to any previously characterized channel proteins. Bestrophins were originally defined as a family of over 20 related sequences of the C. elegans. The first mammalian Bestrophin was identified as the vitelliform macular dystrophy (VMD), 1 also known as Best disease. Three more members of the bestrophin family members were cloned and indentified recently, Bestrophin 2, 3 and 4. RT PCR analyses revealed tissue restricted expression of the three genes with both Bestrophin 1 and Bestrophin 2 are abundantly transcribed in colon. Functionally the bestrophines oligomerise to form tetramers and pentamers in order to act as calcium sensitive chloride channels. It has been shown that Bestrophin interacts with beta catalytic subunit of protein phosphatase 2A (PP2Ac). Such protein protein interaction between Bestrophin and PP2Ac and the structural subunit of PP2A, PR65, was confirmed by reciprocal immunoprecipitation. The interaction between PP2Ac and the Bestrophin takes place near the carboxy terminal end of the protein.
UOM: 1 * 100 µl


Supplier: GRANT INSTRUMENTS
Description: Shaker, Rocking/Rotating Shaker

Catalog Number: (444-1115)
Supplier: Heidolph Instruments GmbH & Co.KG
Description: Platform shaker with three dimensional gyratory motion, designed for homogeneous mixing, ideal for distribution of cells or solutes, preparing slides and electrophoresis gels, culture plates and Erlenmeyer flasks. Polymax 2040 is suitable for large vessels and culture plates. Units have analogue dial controls for adjusting wave frequency and time.
UOM: 1 * 1 items


Catalog Number: (444-0148)
Supplier: VWR Collection
Description: The mini nutating mixer that combines the action of an orbital shaker and a rocker to produce a three-dimensional motion which provides gentle yet thorough mixing without foaming. Ideal for mixing samples in blood and centrifuge tubes. Speed and angle of tilt are fixed, providing the optimum conditions for mixing and re-suspending samples in blood and centrifuge tubes.
UOM: 1 * 1 items


Catalog Number: (444-1343)
Supplier: VWR Collection
Description: The VWR® rotating mixer provides gentle to vigorous mixing of samples in up to 50 ml tubes.
UOM: 1 * 1 items


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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