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Catalog Number: (BOSSBS-6258R-A750)
Supplier: Bioss
Description: A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-12157R-A680)
Supplier: Bioss
Description: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterised by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumour called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-12157R)
Supplier: Bioss
Description: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008].
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-0800R-CY3)
Supplier: Bioss
Description: Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2010].
UOM: 1 * 100 µl


Catalog Number: (700-0245)
Supplier: VWR Collection
Description: The Mini blot shaker combines the actions of a rocker and a shaker to produce a three-dimensional motion that is gentle enough for fragile gels and blots, yet provides thorough mixing.
UOM: 1 * 1 items


Catalog Number: (BOSSBS-12157R-CY7)
Supplier: Bioss
Description: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008].
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-12157R-CY5)
Supplier: Bioss
Description: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008].
UOM: 1 * 100 µl


Supplier: VWR Collection
Description: Shaker, Rocking/Rotating Shaker, VWR®, Capacity: 12×50 ml (12× 25-35Ø mm tube)

Catalog Number: (HAVE210036011)
Supplier: VWR Collection
Description: High reproducibility and comparability.
UOM: 1 * 1 items


Supplier: VWR Collection
Description: Shaker, Vortex Mixer, Replacement cuphead

Environmentally Preferable

Supplier: VWR Collection
Description: Rocking platform shakers have variable speed and adjustable tilt to provide optimum control of mixing conditions, a gentle wave motion is ideal for blotting membranes and gels. Shakers maintain constant speed regardless of load or voltage fluctuations. Durable shakers with choice of models with single- or double-tiered stainless steel platforms.

Catalog Number: (HAVE210886531)
Supplier: VWR Collection
Description: High reproducibility and comparability.
UOM: 1 * 1 items

New Product


Catalog Number: (444-0756)
Supplier: VWR Collection
Description: Rocking platform shaker with low profile design can be used in most fume hoods and incubators. The cast aluminium base offers durability and stability, the spill resistant design channels fluids away from internal components. Precise speed control provides smooth, low speed rocking motion down to one min⁻¹.
UOM: 1 * 1 items


Supplier: VWR Collection
Description: Shaker, Microplate Shaker, Test tube rack, PVC coated steel

Supplier: VWR Collection
Description: Shaker, Rocking/Rotating Shaker, VWR®

Catalog Number: (BOSSBS-12157R-A555)
Supplier: Bioss
Description: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008].
UOM: 1 * 100 µl


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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