You Searched For: Repetitive+Pipettes

Catalog Number: (PRSI79-810)

Supplier: ProSci Inc.

Description: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

UOM: 1 * 100 µG

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Catalog Number: (PRSI31-035)

Supplier: ProSci Inc.

Description: Cyclin H regulates CDK7, the catalytic subunit of the CDK- activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDC2/CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive carboxyl-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. It is involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

UOM: 1 * 100 µG

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Catalog Number: (PRSI77-020)

Supplier: ProSci Inc.

Description: The GARP5 monoclonal antibody specifically reacts with human Glycoprotein A Repetitions Predominant (GARP, also known as LRRC32 or Garpin) molecule, a 80 kDa transmembrane glycoprotein expressed on the cell surface. GARP is expressed in activated Treg cells, placenta, pancreas, liver, skeletal muscle, heart, lung, and kidney, and it acts as a receptor for latent TGF-beta, which down-regulates the Treg cells action.

UOM: 1 * 100 Tests

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Catalog Number: (PRSI50-235)

Supplier: ProSci Inc.

Description: Voltage-gated K+ channels are important determinants of neuronal membrane excitability. Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types (Maletic-Savatic et al., 1995; Pongs, 1999; Blaine and Ribera, 1998; Burger and Ribera, 1996). The Kv3.1 potassium channel is expressed at high levels in neurons that characteristically fire rapid trains of action potentials (Gan et al., 1999). Particularly high levels of this channel are found in neurons of the auditory brainstem. These neurons appear to participate in neural circuits that determine the intensity and timing of auditory stimuli and use this information to determine the location of sounds in space (von Hehn et al., 2004).

UOM: 1 * 100 µl

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Catalog Number: (PRSI31-031)

Supplier: ProSci Inc.

Description: Cdk7 is the catalytic subunit of the CDK-activating kinase (CAK) complex, a serine-threonine kinase. CAK activates the cyclin-associated kinases CDC2/CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive carboxyl-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Cdk7 is involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

UOM: 1 * 100 µG

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Catalog Number: (PRSI29-213)

Supplier: ProSci Inc.

Description: SMN1 localizes to both the cytoplasm and the nucleus. Within the nucleus, the protein localizes to subnuclear bodies called gems which are found near coiled bodies containing high concentrations of small ribonucleoproteins (snRNPs). This protein forms heteromeric complexes with proteins such as SIP1 and GEMIN4, and also interacts with several proteins known to be involved in the biogenesis of snRNPs, such as hnRNP U protein and the small nucleolar RNA binding protein.This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein. However, mutations in this gene, the telomeric copy, are associated with spinal muscular atrophy; mutations in the centromeric copy do not lead to disease. The centromeric copy may be a modifier of disease caused by mutation in the telomeric copy. The critical sequence difference between the two genes is a single nucleotide in exon 7 which is thought to be an exon splice enhancer. It is thought that gene conversion events may involve the two genes, leading to varying copy numbers of each gene. The protein encoded by this gene localizes to both the cytoplasm and the nucleus. Within the nucleus, the protein localizes to subnuclear bodies called gems which are found near coiled bodies containing high concentrations of small ribonucleoproteins (snRNPs). This protein forms heteromeric complexes with proteins such as SIP1 and GEMIN4, and also interacts with several proteins known to be involved in the biogenesis of snRNPs, such as hnRNP U protein and the small nucleolar RNA binding protein. Two transcript variants are produced by this gene.

UOM: 1 * 50 µG

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Catalog Number: (PRSI92-306)

Supplier: ProSci Inc.

Description: Human CCNH, also known as Cyclin-H，MO15-associated protein，p34 and p37, is a protein which belongs to the highly conserved cyclin family. Cyclin family members are characterised by a dramatic periodicity in protein abundance through the cell cycle. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1.CCNH regulates CDK7 which is the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. CCNH is also involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

UOM: 1 * 50 µG

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Catalog Number: (BELAF189380000)

Supplier: Bel-Art Products, a Part of SP

Description: Accurate, repetitive aliquoting into microplate wells is simplified by placing the plate on the adjustable stand and setting the slant to an optimal angle. The slanted plate permits the user to track which wells have received aliquots by visibly contrasting the menisci between adjoining wells.

UOM: 1 * 1 items

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Supplier: VWR Collection

Description: Pipette controller, VWR®

Supplier: VWR Collection

Description: Controller, pipette

Catalog Number: (613-5747)

Supplier: VWR Collection

Description: This power carousel is a comfortable charging solution for up to five electronic pipettes.

UOM: 1 * 1 items

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Catalog Number: (612-7284)

Supplier: VWR Collection

Description: The VWR® pipette filler provides precise fluid control at your fingertips.

UOM: 1 * 1 items

Sale

Catalog Number: (612-1675)

Supplier: VWR Collection

Description: Straw pipettes made from PP, irradiated, disposable, sterile, without graduation.

UOM: 1 * 1.000 items

Certificates Sale

Supplier: VWR Collection

Description: Pipette controller, Pro

Supplier: VWR Collection

Description: Pipette controller, VWR®

Supplier: VWR Collection

Description: Red rubber.