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Image Unavailable-BOSSBS-9174R-A488

Anti-TRIM3 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: Tripartite motif-containing protein 3 (TRIM3), also known as RING finger protein 22 (RNF22), RING finger protein 97 (RNF97) or brain-expressed RING finger protein (BERP), is a 744 amino acid member of the TRIM family, also known as the RING-B-box coiled-coil (RBCC) family. Members of the RBCC family have an N-terminal RING finger, followed by one or two zinc-binding domains (B-box domains), a leucine coiled-coil region and a variable C-terminal domain. Localized to cytoplasmic filaments, TRIM3 has been shown to interact with å-actinin-4 and myosin V, two proteins associated with the actin cytoskeleton. Specifically, å-actinin-4 interacts with the RBCC domain of TRIM3, and the C-terminal tail of Myosin V interacts with with the unique C-terminal ∫-propeller domain of TRIM3. These associations suggest that TRIM3 may play a role in cell motility and cargo transport. Three named isoforms of TRIM3 exist as a result of alternative splicing events.
Catalog Number: BOSSBS-9174R-A488
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-9173R-HRP

Anti-RNF8 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: The RING finger motif is a specialized DNA-binding zinc finger domain found in many transcriptional regulatory proteins. The ring finger protein (RNF) family includes any protein containing the signature RING finger motif. RNF8 is a ubiquitously expressed nuclear RING finger protein that acts as an E3 ubiquitin-protein ligase. It is required for the ubiquitination of some nuclear proteins and promotes their subsequent degradation. The heterodimeric ubiquitin-conjugating enzyme UBC13 interacts with RNF8, and they co-localize in the nucleus. RNF8 may regulate mediation of UBC13 polyubiquitylation by elongating the ubiquitin chains. RNF8 also binds to Retinoid X receptor alpha (RXR?, a member of the steroid hormone receptor superfamily. It increases RXR?mediated transactivation of the RXR?responsive element (RXRE) promoter in a dose-dependent manner, suggesting that RNF8 is a regulator of RXR?mediated transcriptional activity.
Catalog Number: BOSSBS-9173R-HRP
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-9145R-A750

Anti-UBOX5 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: The U-box domain is a modified RING finger motif that has been implicated in the ubiquitin/proteasome system. The ubiquitin-conjugating enzyme 7-interacting protein 5 (UIP5), also designated U-box domain-containing protein 5 or RING finger protein 37, contains 1 RING-type zinc finger and 1 U-box domain. UIP5 has been shown to interact with UBCH7, an enzyme that mediates selective degradation of abnormal proteins. The gene encoding UIP5 maps to chromosome 20, which houses over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.
Catalog Number: BOSSBS-9145R-A750
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-9145R-A488

Anti-UBOX5 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: The U-box domain is a modified RING finger motif that has been implicated in the ubiquitin/proteasome system. The ubiquitin-conjugating enzyme 7-interacting protein 5 (UIP5), also designated U-box domain-containing protein 5 or RING finger protein 37, contains 1 RING-type zinc finger and 1 U-box domain. UIP5 has been shown to interact with UBCH7, an enzyme that mediates selective degradation of abnormal proteins. The gene encoding UIP5 maps to chromosome 20, which houses over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.
Catalog Number: BOSSBS-9145R-A488
UOM: 1 * 100 µl
Supplier: Bioss
Product Image-NITRGSG10NITXLMA

Sterile sleeve/glove system, BioClean™

Description: Clean and sterile sleeve/glove system, nitrile sleeve attached to an ambidextrous polychloroprene (BioClean S-BFAP) glove by a channel ring and O-ring.
Catalog Number: NITRGSG10NITXLMA
UOM: 1 * 10 PAIR
Supplier: Nitritex
Product Image-663-0377

Multiparameter photometer, Water-ID® The PrimeLab 2.0

Description: The next generation of multitest Photometer, with pH - EC - TDS - ORP - Temperature measurement functionality.
Catalog Number: 663-0377
UOM: 1 * 1 items
Supplier: WATER ID PRIMELAB
Image Unavailable-BOSSBS-9262R

Anti-RNF186 Rabbit Polyclonal Antibody

Description: The RING finger motif is a specialized DNA-binding zinc finger domain found in many transcriptional regulatory proteins. The ring finger protein (RNF) family includes any protein containing the signature RING finger motif. RNF186 (RING finger protein 186) is a 227 amino acid multi-pass membrane protein containing one RING-type zinc finger. The gene encoding RNF186 maps to human chromosome 1p36.13. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.
Catalog Number: BOSSBS-9262R
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-9262R-CY5

Anti-RNF186 Rabbit Polyclonal Antibody (Cy5®)

Description: The RING finger motif is a specialized DNA-binding zinc finger domain found in many transcriptional regulatory proteins. The ring finger protein (RNF) family includes any protein containing the signature RING finger motif. RNF186 (RING finger protein 186) is a 227 amino acid multi-pass membrane protein containing one RING-type zinc finger. The gene encoding RNF186 maps to human chromosome 1p36.13. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.
Catalog Number: BOSSBS-9262R-CY5
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-1372R

Anti-PSMD9 Rabbit Polyclonal Antibody

Description: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD9 is a non-ATPase subunit of the 19S regulator.
Catalog Number: BOSSBS-1372R
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-9174R-FITC

Anti-TRIM3 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: Tripartite motif-containing protein 3 (TRIM3), also known as RING finger protein 22 (RNF22), RING finger protein 97 (RNF97) or brain-expressed RING finger protein (BERP), is a 744 amino acid member of the TRIM family, also known as the RING-B-box coiled-coil (RBCC) family. Members of the RBCC family have an N-terminal RING finger, followed by one or two zinc-binding domains (B-box domains), a leucine coiled-coil region and a variable C-terminal domain. Localized to cytoplasmic filaments, TRIM3 has been shown to interact with å-actinin-4 and myosin V, two proteins associated with the actin cytoskeleton. Specifically, å-actinin-4 interacts with the RBCC domain of TRIM3, and the C-terminal tail of Myosin V interacts with with the unique C-terminal ∫-propeller domain of TRIM3. These associations suggest that TRIM3 may play a role in cell motility and cargo transport. Three named isoforms of TRIM3 exist as a result of alternative splicing events.
Catalog Number: BOSSBS-9174R-FITC
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-9173R-A680

Anti-RNF8 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: The RING finger motif is a specialised DNA-binding zinc finger domain found in many transcriptional regulatory proteins. The ring finger protein (RNF) family includes any protein containing the signature RING finger motif. RNF8 is a ubiquitously expressed nuclear RING finger protein that acts as an E3 ubiquitin-protein ligase. It is required for the ubiquitination of some nuclear proteins and promotes their subsequent degradation. The heterodimeric ubiquitin-conjugating enzyme UBC13 interacts with RNF8, and they co-localise in the nucleus. RNF8 may regulate mediation of UBC13 polyubiquitylation by elongating the ubiquitin chains. RNF8 also binds to Retinoid X receptor alpha (RXR?, a member of the steroid hormone receptor superfamily. It increases RXR?mediated transactivation of the RXR?responsive element (RXRE) promoter in a dose-dependent manner, suggesting that RNF8 is a regulator of RXR?mediated transcriptional activity.
Catalog Number: BOSSBS-9173R-A680
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-6757R

Anti-BCA2 Rabbit Polyclonal Antibody

Description: The RING finger family of proteins possess ubiquitin ligase activity and play pivotal roles in protein degradation and receptor-mediated endocytosis. The autoubiquitination activity of ZNF364 indicates that it is a novel RING-type E3 ligase. Its effects on cell growth indicate that ZNF364 may be important for the ubiquitin modification of proteins crucial to breast carcinogenesis and growth.
Catalog Number: BOSSBS-6757R
UOM: 1 * 100 µl
Supplier: Bioss
Product Image-BOHLD583-14

Connectors, for GL threaded connections

Description: Connector made from PP with elastic sealing lip and FPM O-ring
Catalog Number: BOHLD583-14
UOM: 1 * 1 items
Supplier: Bohlender
Image Unavailable-DISI2800-0954

Accessories for Autoclavable Bioreactor Assemblies, BIOne

Description: Bioreactor, accessories, Autoclavable accessory kit for all microbial applications and the 10 L cell culture system. Kit includes O-rings, cable ties, hose clamps, silicone tubing, exhaust filters, and septum.
Catalog Number: DISI2800-0954
UOM: 1 * 1 items
Supplier: DISTEK
Image Unavailable-BOSSBS-6757R-A555

Anti-BCA2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Description: The RING finger family of proteins possess ubiquitin ligase activity and play pivotal roles in protein degradation and receptor-mediated endocytosis. The autoubiquitination activity of ZNF364 indicates that it is a novel RING-type E3 ligase. Its effects on cell growth indicate that ZNF364 may be important for the ubiquitin modification of proteins crucial to breast carcinogenesis and growth.
Catalog Number: BOSSBS-6757R-A555
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-9264R-CY5.5

Anti-RNF215 Rabbit Polyclonal Antibody (Cy5.5®)

Description: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF215 (ring finger protein 215), is a 377 amino acid multi-pass membrane protein containing one RING-type zinc finger. The gene encoding RNF215 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
Catalog Number: BOSSBS-9264R-CY5.5
UOM: 1 * 100 µl
Supplier: Bioss
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