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Image Unavailable-PRSI33-858

Anti-TP53 Mouse Monoclonal Antibody [clone: PAb 1801]

Catalog Number: (PRSI33-858)
Supplier: ProSci Inc.
Description: This mAb reacts with an N-terminal epitope (aa 32-79) of both wild type and mutated p53. Mutation and/or allelic loss of p53 is one of the causes of a variety of mesenchymal and epithelial tumors. If it occurs in the germ line, such tumors run in families. In most transformed and tumor cells the concentration of p53 is increased 5-1000 fold over the minute concentrations (1000 molecules cell) in normal cells, principally due to the increased half-life (4 h) compared to that of the wild-type (20 min). It localizes in the nucleus, but is detectable at the plasma membrane during mitosis and when certain mutations modulate cytoplasmic/nuclear distribution. Mutations arise with an average frequency of 70% but incidence varies from zero in carcinoid lung tumors to 97% in primary melanomas. High concentrations of p53 protein are transiently expressed in human epidermis and superficial dermal fibroblasts following mild ultraviolet irradiation. Positive nuclear staining with specific antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia.
UOM: 1 * 100 µG
Product Image-A1069.1000

HEPES (2-[4-(2-hydroxyethyl)-1-piperazinyl]ethanesulphonic acid) ≥99.5% suitable for buffer solutions

Supplier: PanReac AppliChem
Description: HEPES (2-[4-(2-hydroxyethyl)-1-piperazinyl]ethanesulphonic acid) ≥99.5% suitable for buffer solutions

Image Unavailable-40020.

Aminoallyl-dUTP (AA-dUTP) sodium salt 10 mM in TE buffer

Catalog Number: (40020.)
Supplier: Biotium
Description: 5-Aminoallyl-dUTP (AA-dUTP) can be enzymatically incorporated into DNA. The resulting amine-containing DNA can be subsequently labeled with a fluorescent dye, biotin or other haptens via conventional peptide coupling method.
UOM: 1 * 100 µl
Product Image-23006.

Flow cytometry fixation/permeabilisation kit

Catalog Number: (23006.)
Supplier: Biotium
Description: Flow Cytometry Fixation/Permeabilisation Kit contains optimally formulated buffers for fixation and permeabilisation of suspension cells for immunofluorescence staining of intracellular antigens for analysis by flow cytometry. The bufffers are also available separately.
UOM: 1 * 50 Tests

Certificates


Image Unavailable-J60357.AD

TBE sample buffer (6X)

Supplier: Thermo Fisher Scientific
Description: Loading Buffer, TBE Sample Buffer, 6X

MSDS Certificates

Product Image-786-184HP

Protein purification kit, STRATEGY™

Supplier: G-Biosciences
Description: STRATEGY™ is designed to allow researchers to rapidly screen a number of purification techniques in a small scale format to identify the system to isolate their protein of interest. The self-contained kit allows researchers to save time and money as separate buffers, resins and columns are not needed.

Image Unavailable-SIALP3813-1PAK

Buffer, PBS solution (phosphate buffered saline) pH 7,4, Sigma-Aldrich®

Supplier: Merck
Description: Washing buffer, PBS buffer solution (phosphate buffered saline) pH 7,4

Image Unavailable-A1085.1000

Tricine

Supplier: PanReac AppliChem
Description: Tricine

Product Image-ACE-1311-7530

Avantor® ACE® SuperC18, HPLC Columns, 10 µm

Supplier: Avantor
Description: Avantor® ACE® SuperC18 columns provide high stability across an extended pH range. These stainless steel columns are ideal for use with LC/MS compatible buffers and can be used with both MeOH and MeCN mobile phases.

Image Unavailable-A8569.0500

Buffer, TE Solution (TRIS-EDTA buffer) pH 8,0, Low EDTA for Molecular Biology

Supplier: PanReac AppliChem
Description: Cloning Buffer, TE buffer solution (TRIS-EDTA buffer) pH 8,0

Image Unavailable-A14695.22

Tricine ≥98%

Supplier: Thermo Fisher Scientific
Description: Tricine ≥98%

MSDS Certificates

Image Unavailable-H3292-50ML

Histo/Zyme

Supplier: SIGMA ALDRICH MICROSCOPY
Description: Histo/Zyme is a stabilized proteolytic enzyme in buffered solution, used to unmask immunoreactive sites altered by fixation and/or the embedding process. Treatment with a proteolytic enzyme in immunohistochemistry (IHC) is required to digest excess linkages and expose the antigen. The use of Histo/Zyme results in superior staining over traditionally used enzyme pretreatments, such as pepsin and trypsin. Moreover, Histo/Zyme requires only a brief incubation at room temperature. Performing antigen recovery with Histo/Zyme will allow you to dilute the primary antibody 5 to 10 fold further and achieve optimal staining.

Image Unavailable-J63666.K2

Citrate-buffered saline (20X)

Supplier: Thermo Fisher Scientific
Description: Saline-sodium citrate (SSC) buffer.

MSDS Certificates

Image Unavailable-AGLS600382

PfuUltra high-fidelity DNA polymerase

Supplier: AGILENT
Description: PfuUltra High-Fidelity DNA Polymerase AD features a reformulated buffer system for increased economy with the same high performance as the original PfuUltra DNA Polymerase for robust, ultra-high-fidelity PCR.

Product Image-PIER37549

North2South™ Hybridisation Buffer

Catalog Number: (PIER37549)
Supplier: Thermo Fisher Scientific
Description: North2South™ hybridisation buffer is an aqueous buffer which is used with the North2South™ chemiluminescent detection kit.
UOM: 1 * 125 mL
Image Unavailable-J62052.AK

Sodium pyrophosphate, 200 mM buffer solution

Supplier: Thermo Fisher Scientific
Description: Cloning Buffer, Sodium pyrophosphate, 200mM buffer solution

MSDS Certificates

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
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The original product is no longer available. The replacement shown is available.
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