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Anti-NDUFS7 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-11734R-CY7)

Supplier: Bioss

Description: Located in the mitochondrial inner membrane, mitochondrial complex I is the first and largest enzyme in the electron transport chain of oxidative phosphorylation. By oxidizing NADH that is produced in the Krebs cycle, this complex utilizes the two electrons to reduce ubiquinone to ubiquinol, thereby initiating the passage of electrons to successive complexes and ultimately leading to the reduction of oxygen to water. Mitochondrial complex I consists of over 40 subunits and is of considerable clinical interest since defects in any of the subunits can lead to various myopathies and neuropathies. As a subunit of mitochondrial complex I, NDUFS7 (NADH dehydrogenase [ubiquinone] iron-sulfur protein 7), also designated NADH-ubiquinone oxidoreductase 20 kDa subunit, is a 213 amino acid protein that is suggested to be required for catalytic activity. Defects in the gene encoding NDUFS7 are the cause of Leigh syndrome, a severe neurological disorder that is characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions.

UOM: 1 * 100 µl

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Anti-SLC25A28 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-7157R-HRP)

Supplier: Bioss

Description: Mitoferrin 2, also known as MRS3/4 (mitochondrial RNA-splicing protein 3/4 homolog), mitochondrial iron transporter 2, NPD016, MRS4L or SLC25A28 (solute carrier family 25 member 28), is a 364 amino acid multi-pass membrane protein of the mitochondrial inner membrane that mediates iron uptake. Mitoferrin 2 is thought to play a role in heme synthesis of hemoproteins and iron-sulfur cluster assembly. Ubiquitously expressed, Mitoferrin 2 is found at high levels in skeletal muscle, heart, placenta, kidney, lung, liver, brain and pancreas. Mitoferrin 2 is a member of the mitochondrial carrier family and undergoes alternative splicing events to produce four isoforms. Mitoferrin 2 contains three solcar repeats and is encoded by a gene that maps to human chromosome 10q24.2.

UOM: 1 * 100 µl

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Sulphuric acid 25% (by acidimetry) analytical reagent

Supplier: PanReac AppliChem

Description: Sulphuric Acid for analysis

Ammonium sulphate 99.0-100.5%, granular, BAKER ANALYZED® FCC, ACS for biochemistry, for chromatography endotoxin tested, J.T.Baker®

Catalog Number: (0793-08)

Supplier: Avantor

Description: Ideal for biotechnology, cell biology and molecular biology discovery, and biopharmaceutical production, J.T.Baker® brand denaturants offer high purity, low insolubles and heavy metals with minimal contaminants. Extensive experience in managing the risks associated with handling and mixing large volumes of corrosive materials has enabled us to provide custom solutions perfectly suited to your needs.

UOM: 1 * 325 lb

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