You Searched For: Tetrahydrofurfuryl+acrylate

Description: Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver. Required for the expression of several liver specific genes. Binds to the inverted palindrome 5'-GTTAATNATTAAC-3'.

Catalog Number: BOSSBS-1405R-CY5.5

UOM: 1 * 100 µl

Supplier: Bioss

Sale

Description: Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.

Catalog Number: BOSSBS-3777R-CY7

UOM: 1 * 100 µl

Supplier: Bioss

Sale

Description: Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 4 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Activation requires recruitment of transcriptional coactivators such as CREBPB and EP3. Activity is enhanced by interaction with both, NCOA1 or NCOA2. Interaction with redox regulatory protein APEX seems to activate CTAD and potentiates activation by NCOA1 and CREBBP. Involved in the axonal distribution and transport of mitochondria in neurons during hypoxia.

Catalog Number: BOSSBS-0737R-CY5

UOM: 1 * 100 µl

Supplier: Bioss

Sale

Description: Anti-OR11A1 Rabbit Polyclonal Antibody (Biotin)

Catalog Number: USBI039316-BIOTIN

UOM: 1 * 200 µl

Supplier: US Biological

Sale

Description: Anti-HNF1A Rabbit Polyclonal Antibody (Biotin)

Catalog Number: USBIT2020-22-BIOT

UOM: 1 * 200 µl

Supplier: US Biological

Sale

Description: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.

Catalog Number: BOSSBS-8680R-CY3

UOM: 1 * 100 µl

Supplier: Bioss

Sale

Description: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.

Catalog Number: BOSSBS-8680R-CY5

UOM: 1 * 100 µl

Supplier: Bioss

Sale

Description: Anti-TCF1/HNF1A Rabbit Polyclonal Antibody

Catalog Number: BOSSBS-1405R

UOM: 1 * 100 µl

Supplier: Bioss

Sale

Description: Anti-HIF1A Rabbit Polyclonal Antibody (Biotin)

Catalog Number: NOVUNBP1-47180B

UOM: 1 * 0,1 mL

Supplier: Novus Biologicals

Sale

Description: Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 4 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Activation requires recruitment of transcriptional coactivators such as CREBPB and EP3. Activity is enhanced by interaction with both, NCOA1 or NCOA2. Interaction with redox regulatory protein APEX seems to activate CTAD and potentiates activation by NCOA1 and CREBBP. Involved in the axonal distribution and transport of mitochondria in neurons during hypoxia.

Catalog Number: BOSSBS-0737R-CY3

UOM: 1 * 100 µl

Supplier: Bioss

Sale

Description: Anti-HIF1A Rabbit Polyclonal Antibody (Biotin)

Catalog Number: NOVUNB100-134B

UOM: 1 * 0,1 mL

Supplier: Novus Biologicals

Sale

Description: Anti-HIF1A Rabbit Polyclonal Antibody (Biotin)

Catalog Number: NOVUNB100-654B

UOM: 1 * 0,1 mL

Supplier: Novus Biologicals

Sale

Description: Anti-Adenovirus 9 E4 Orf1 Rabbit Polyclonal Antibody

Catalog Number: BIRBORB75040-100

UOM: 1 * 100 µG

Supplier: Biorbyt

Sale

Description: Adenovirus-9 E4 Orf1 Antibody: The many different serotypes of human adenoviruses (Ad) are divided into six subgroups, of which all Ad subgroup A and B and two subgroup D Ads can elicit tumors in infected rodents. Unlike the Ads from subgroup A and B, the ones from subgroup D, Ad9 and Ad10 elicit estrogen-dependent mammary tumors as opposed to undifferentiated sarcomas. In the case of Ad9, its tumorigenicity is dependent on the product of the open reading frame (ORF) 1 of the early region 4 (E4). The tumorigenic potential of Ad9 E4 Orf1 depends on a carboxyl-terminal PDZ domain-binding motif that mediates interactions with several different membrane-associated cellular proteins such as MUPP1, PATJ, MAGI-1, ZO-2 and Dlg1. It has been suggested that Ad9 E4 Orf1 may have evolved from an ancestral cellular dUTP pyrophosphatase.

Catalog Number: PRSI4749

UOM: 1 * 100 µG

Supplier: ProSci Inc.

Sale

Description: Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.

Catalog Number: BOSSBS-3777R-CY3

UOM: 1 * 100 µl

Supplier: Bioss

Sale

Description: Anti-OR4F17 Rabbit Polyclonal Antibody (Biotin)

Catalog Number: USBI039394-BIOTIN

UOM: 1 * 200 µl

Supplier: US Biological

Sale