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Product Image-552-0217

TLC plates, mixed layers, glass backing

Catalog Number: (552-0217)
Supplier: MACHEREY-NAGEL
Description: Glass plates with mixed layers for TLC.
UOM: 1 * 25 items
Image Unavailable-HYPE60300-482

SPE plates, 96-well, HyperSep™, Silica

Supplier: Thermo Fisher Scientific
Description: Thermo Scientific™ HyperSep Silica SPE 96-Well Plates and Individual Wells feature a polar sorbent primarily used to retain analytes in non polar matrices, and can effectively separate compounds of very similar structure.

Image Unavailable-ENZOALX106001M025

Nω-Methyl-L-arginine monoacetate ≥99% (by TLC)

Supplier: ENZO LIFE SCIENCES
Description: Competitively inhibits the generation of NO from arginine and is a useful tool for inhibition of NO mediated effects. In vitro, L-NMMA inhibits relaxation of rat aorta rings induced by acetylcholine (IC50=9.5µM). In vivo, it causes a dose dependent increase in mean arterial blood pressure in anesthetized rats (EC50=16.7mg/kg).

Image Unavailable-CAMA034.1798

TLC plates, silica gel 60, precoated

Catalog Number: (CAMA034.1798)
Supplier: CAMAG
Description: TLC precoated sheets, silica gel 60.
UOM: 1 * 25 items
Image Unavailable-50038.

Furaptra (Mag-Fura-2) AM Ester ≥95% (by TLC) fluorescent indicator, for calcium determination

Supplier: Biotium
Description: Furaptra, AM ester is a membrane-permeant form of Furaptra (Mag-Fura-2). The indicator is loaded into cells via simple incubation

Image Unavailable-ENZOBMLEI3120005

SB216763 ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES
Description: Potent and selective inhibitor of GSK-3β (IC50=34nM). Stimulates glycogen synthesis in human liver cells and mimics other actions of insulin. Protects primary neurons from death induced by PI-3 kinase pathway inhibition suggesting therapeutic potential in neurodegenerative diseases and stroke. Reduces pulmonary inflammation and fibrosis in a mouse model.

Image Unavailable-VARI12162054B

Solid phase extraction cartridges, Bond Elut™ Sodium Sulphate Drying

Supplier: VARIAN
Description: Bond Elut™ Jr cartridges have top and bottom Luer fittings allowing easy sample processing when used in conjunction with standard SPE cartridges. Bond Elut™ LRC cartridges have a large reservoir above the sorbent bed and are suitable for use on any standard SPE vacuum manifold.

Image Unavailable-50006.

5,5'-difluoro BAPTA tetrapotassium salt ≥95% (by TLC) ion chelator, for calcium determination

Catalog Number: (50006.)
Supplier: Biotium
Description: BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an important means to study the roles of calcium.
UOM: 1 * 100 mg
Image Unavailable-90029.

5-Carboxyfluorescein-N-succinimidyl ester (5-FAM SE) ≥99% (by TLC) amine-reactive fluorescent dye

Catalog Number: (90029.)
Supplier: Biotium
Description: 5-FAM SE is an amine-reactive form of 5-carboxyfluorescein single isomer.
UOM: 1 * 10 mg
Image Unavailable-ENZOALX380237M010

Ristocetin A sulphate ≥95% (by HPLC)

Catalog Number: (ENZOALX380237M010)
Supplier: ENZO LIFE SCIENCES
Description: Potent antibacterial antibiotic. It induces platelet aggregation by binding to a factor absent in people suffering from von Willebrand’s disease and is therefore an important diagnostic tool. Chiral selector for the separation of enantiomers by HPLC, TLC and electrophoresis.
UOM: 1 * 10 mg
Image Unavailable-ENZOBMLST3400005

Haloenol lactone suicide substrate ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES
Description: HELSS is a potent, irreversible, mechanism-based inhibitor of Ca2+-independent PLA2 (70% inhibition at 100 nM). It possesses a 1000-fold selectivity for Ca2+-independent PLA2 vs. Ca2+-dependent PLA2 . It has been used to identify the PLA2 involved in the release of arachidonate induced by vasopressin stimulation of A-10 smooth muscle cells (IC50=1 µM). It has also been shown to inhibit the Mg2+-dependent phophatidate phosphohydrolase from P388D1 macrophages (IC50~8 µM).

Image Unavailable-ENZOBMLFA0170025

Anandamide ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES
Description: Endogenous [1] ligand for the CB1 receptor (CB1: Ki=52nm; CB2: Ki=1930nm [2]) and TRPV1 (Ki=5.78µM [3,4]). Inhibits NF-κB activation through direct binding to IKKβ [5] and induces apoptosis independently of cannabinoid or vanilloid receptors [6]. Activates the MAP kinase (MAPK/ERK) signalling pathway [7].

Image Unavailable-ENZOBMLEI3070005

GW5074 ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES
Description: Potent and selective cell permeable inhibitor of cRAF1 kinase (IC50 = 9 nM) with 100-fold selectivity over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. A useful tool for assessing the involvement of the Ras/Raf-1/ERK pathway in various signaling pathways. Displays neuroprotective effects in vivo through a MEK-ERK and Akt-independent mechanism.

Image Unavailable-ENZOBMLEI3470050

DMOG ≥99% (by TLC)

Supplier: ENZO LIFE SCIENCES
Description: DMOG is a cell permeable prolyl-4-hydroxylase inhibitor which upregulates HIF activity. HIF activation stimulates angiogenesis in several different models. DMOG also inhibits FIH (Factor Inhibiting HIF), an asparaginyl hydroxylase, which enhances the HIF response. It is active in vivo and attenuates myocardial injury in a rabbit ischemia reperfusion model (20mg/kg). Is expected to act pro-angiogenic.

Product Image-552-0213

TLC plates, silica gel 60, unmodified layers, with concentrating zone, SILGUR

Supplier: MACHEREY-NAGEL
Description: Unmodified standard silica layers with concentrating zone for TLC.

Image Unavailable-ENZOALX350002M100

L-Canavanine sulphate ≥99% (by TLC)

Supplier: ENZO LIFE SCIENCES
Description: The non-protein amino acid L-canavanine is an analog of L-arginine. Selective inducible nitric oxide synthase (iNOS; NOS II) inhibitor. Induces apoptotic cell death and shows antiproliferative and immunotoxic effects.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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